18F-prostate-specific membrane antigen positron emission tomography computed tomography incidental finding in a patient after COVID-19 infection

Siroos Mirzaei; Cherin Farhan; Mario Karolyi

doi:10.4103/wjnm.WJNM_110_20

World Journal of Nuclear Medicine, Table of Contents

CC BY-NC-ND 4.0 · World J Nucl Med 2020; 19(04): 455-456
DOI: 10.4103/wjnm.WJNM_110_20

Interesting Cases

¹⁸F-prostate-specific membrane antigen positron emission tomography computed tomography incidental finding in a patient after COVID-19 infection

Siroos Mirzaei

Department of Nuclear Medicine with PET-Center, Klinik Ottakring, Vienna, Austria

,

Cherin Farhan

Department of Nuclear Medicine with PET-Center, Klinik Ottakring, Vienna, Austria

,

Mario Karolyi

¹Department for Infectious Diseases and Tropical Medicine, Klinik Favoriten (KFJ), Vienna, Austria

› Author Affiliations

Abstract

The COVID-19 pandemic has now reached most countries. However, the referred patients to a nuclear medicine department will be primarily the asymptomatic ones. We report the case of a patient (84-year-old male) who was sent for ¹⁸F-prostate-specific membrane antigen positron emission tomography computed tomography (PSMA PET-CT) with suspicion of recurrent disease after prostate cancer and total prostatectomy 2 years prior to the examination. He suffered from COVID-19 pneumonia 4 weeks prior to PET-CT examination. The ¹⁸F-PSMA PET-CT revealed moderate elevated uptake in the area of previous pneumonia in the right lung. The radiological findings showed ground glass changes in this area indicating possible residual inflammatory disease even weeks after infection.

Keywords

¹⁸F-prostate-specific membrane antigen - COVID-19 - infection - positron emission tomography computed tomography - prostate cancer

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References

References
1 Czernin J, Fanti S, Meyer PT, Allen-Auerbach M, Hacker M, Sathekge M, et al. Imaging clinic operations in the times of COVID-19: Strategies, Precautions and Experiences. J Nucl Med 2020;47:2038-9..
2 Paez D, Gnanasegaran G, Fanti S, Bomanji J, Hacker M, Sathekge M, et al. COVID-19 pandemic: Guidance for nuclear medicine departments. Eur J Nucl Med Mol Imaging 2020;47:1615-9.
3 Setti L, Kirienko M, Dalto SC, Bonacina M, Bombardieri E. FDG-PET/CT findings highly suspicious for COVID-19 in an Italian case series of asymptomatic patients. Eur J Nucl Med Mol Imaging 2020;47:1649-56.
4 Grubmüller B, Baum RP, Capasso E, Singh A, Ahmadi Y, Knoll P, et al. (64) Cu-PSMA-617 PET/CT imaging of prostate adenocarcinoma: First in-human studies. Cancer Biother Radiopharm 2016;31:277-86.
5 Sharif-Paghaleh E, Yap ML, Puh SL, Adam Badar A, Torres JB, Chuamsaamarkkee K, Kampmeier F, et al. Non-invasive whole-body detection of complement activation using radionuclide imaging in a mouse model of myocardial ischaemia-reperfusion injury. Sci Rep 2018;8:4687.