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CC BY-NC-ND 4.0 · World J Nucl Med 2020; 19(04): 425-427
DOI: 10.4103/wjnm.WJNM_18_20
Case Report

Extrapleural solitary fibrous tumor evidenced by 68Ga-prostate-specific membrane antigen positron emission tomography/computed tomography study in the staging of a high-risk prostate cancer patient

André Braga Ribeiro
Department of Nuclear Medicine, A. C. Camargo Cancer Center, São Paulo, Brazil
,
Thais Nascimento
Department of Nuclear Medicine, A. C. Camargo Cancer Center, São Paulo, Brazil
,
Eduardo Lima
Department of Nuclear Medicine, A. C. Camargo Cancer Center, São Paulo, Brazil
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Abstract

Positron emission tomography/computed tomography (PET/CT) using 68Ga-labeled prostate-specific membrane antigen (68Ga-PSMA) became an important tool in the prostate cancer (PC) diagnosis. Despite its high sensitivity and specificity, this method may produce false-positive findings, as indicated by previous studies. This case report aims to warn nuclear medicine physicians, oncologists, and urologists about the possibility of false-positive findings using this imaging modality, especially in patients who have already been diagnosed with other malignancies. A 69-year-old man, previously treated for an extrapleural solitary fibrous tumor (ESFT), underwent staging tests after a new diagnosis of high-risk PC. 68Ga-PSMA PET/CT imaging revealed an abnormal uptake in the prostate and in the right humerus. A biopsy was performed, and the pathology showed a lesion consisting of an ESFT metastasis. Diagnostic issues related to 68Ga-PSMA PET/CT imaging should be disseminated to help physicians make appropriate treatment choices for each patient and avoid unnecessary procedures.

Keywords

68Ga-prostate-specific membrane antigen - bone metastasis - extrapleural solitary fibrous tumor - false-positive result - prostate cancer

Financial support and sponsorship

Nil.




Publication History

Received: 06 March 2020

Accepted: 31 March 2020

Article published online:
19 April 2022

© 2020. Sociedade Brasileira de Neurocirurgia. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commecial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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