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CC BY-NC-ND 4.0 · World J Nucl Med 2018; 17(04): 213-218
DOI: 10.4103/wjnm.WJNM_56_17
Original Article

Quantitative accuracy of positron emission tomography/magnetic resonance and positron emission tomography/computed tomography for cervical cancer

Jorge Daniel Oldan
Department of Radiology, Division of Nuclear Medicine, University of North Carolina, Chapel Hill, NC
,
Amir Hossein Khandani
Department of Radiology, Division of Nuclear Medicine, University of North Carolina, Chapel Hill, NC
,
Julia R. Fielding
1   Department of Radiology, Division of Abdominal Radiology, University of Texas-Southwestern, Dallas, Texas, USA
,
Ellen Louise Jones
2   Department of Radiation Oncology, University of North Carolina, Chapel Hill, NC
,
Paola Alvarez Gehrig
3   Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, University of North Carolina, Chapel Hill, NC
,
Tiffany Sills
4   Department of Radiology, University of North Carolina, Chapel Hill, NC
,
Pinakpani Roy
5   Department of Radiology, Stanford University, Palo Alto, CA
,
Weili Lin
6   6Biomedical Research Imaging Center, Chapel Hill, NC
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With the spread of positron emission tomography/magnetic resonance (PET/MR), the question of comparability of studies becomes important. We aim to determine whether PET/MR and PET/computed tomography (PET/CT) are comparable for the case of cervical cancer. Fifteen cervical cancer patients identified by either a radiation oncologist or an oncologic surgeon had both PET/MR and PET/CT performed for initial staging within 3 weeks. We then compared the results both quantitatively (measuring standardized uptake values [SUVs] on visible lesions) as well as qualitatively (having radiologists and nuclear medicine physicians interprets the results). While interpretations between PET/MR and PET/CT varied in many cases, SUVs of primary lesions were similar to within 25% in all but one case, and correlation coefficient was 0.92. Maximum SUV ranged between 4.9 and 25.2 for PET-MR and between 5.8 and 30.4 for PET-CT for primary tumors and between 1.5 and 18.8 for PET-MR and between 1.8 and 20.8 for PET-CT for nodes. However, clinical reads often varied significantly between PET/MR and PET/CT. This suggests that SUV is similar on PET/MR and PET/CT although the differing anatomic modalities available for correlation may make the difference in terms of qualitative interpretation.

Keywords

Cervical cancer - positron emission tomography/computed tomography - positron emission tomography/magnetic resonance - standardized uptake value


Publication History

Received: 00 00 2018

Accepted: 00 00 2018

Article published online:
22 April 2022

© 2018. Sociedade Brasileira de Neurocirurgia. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commecial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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