CC BY-NC-ND 4.0 · World J Nucl Med 2020; 19(03): 310-312
DOI: 10.4103/wjnm.WJNM_59_20
Case Report

Diffuse pleural metastases of osteosarcoma detected by bone scan

André Ribeiro
Department of Nuclear Medicine, A. C. Camargo Cancer Center, Liberdade, São Paulo, Brazil
,
Eduardo Lima
Department of Nuclear Medicine, A. C. Camargo Cancer Center, Liberdade, São Paulo, Brazil
,
Daniel Lima
Department of Nuclear Medicine, A. C. Camargo Cancer Center, Liberdade, São Paulo, Brazil
› Author Affiliations

Abstract

Osteosarcoma (OS) is a fast-growing tumor, with a high risk of local recurrence and distant metastases, with the lung and bone being the most common sites of dissemination occurring in approximately 80% of cases. Pleural metastases rarely occurs and the appearance of diffuse pleural thickening with ossification is not usual, with few such cases reported due to the current state-of-art treatment protocols. A 29-year-old woman, diagnosed with a proximal left tibial OS underwent planar and single-photon emission computed tomography/computed tomography bone scan scintigraphy with 99mtechnetium methylene diphosphonate showing bilateral pleural uptake, corresponding to multiple calcified foci of thickening and nodules.

Financial support and sponsorship

Nil.




Publication History

Received: 01 June 2020

Accepted: 26 June 2020

Article published online:
19 April 2022

© 2020. Sociedade Brasileira de Neurocirurgia. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commecial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

Thieme Medical and Scientific Publishers Pvt. Ltd.
A-12, 2nd Floor, Sector 2, Noida-201301 UP, India

 
  • References

  • 1 Pochanugool L, Subhadharaphandou T, Dhanachai M, Hathirat P, Sangthawan D, Pirabul R, et al. Prognostic factors among 130 patients with osteosarcoma. Clin Orthop Relat Res 1997;345:206-14.
  • 2 Lindsey BA, Markel JE, Kleinerman ES. Osteosarcoma overview. Rheumatol Ther 2017;4:25-43.
  • 3 Rastogi R, Garg R, Thulkar S, Bakhshi S, Gupta A. Unusual thoracic CT manifestations of osteosarcoma: Review of 16 cases. Pediatr Radiol 2008;38:551-8.
  • 4 Geller DS, Gorlick R. Osteosarcoma: A review of diagnosis, management, and treatment strategies. Clin Adv Hematol Oncol 2010;8:705-18.
  • 5 Marchiori E, Menna Barreto M, Zanetti G. Pleural metastases of osteosarcoma. Ann Thorac Surg 2018;105:e87-e88.
  • 6 Krishnamurthy K, Alghamdi S, Kochiyil J, Bruney GF, Poppiti RJ. Osteosarcoma presenting with malignant pleural effusion in a 55 year old. Respir Med Case Rep 2018;25:314-7.
  • 7 Sukumaran R, Nayak N, Mony R, Kaur J, Nair S: Osteosarcoma presenting with massive malignant pleural effusion. Oncol J India 2019;3:20.
  • 8 Palestro CJ, Styles ST, Kim CK, Goldsmith SJ. Bone scintigraphy in pleural metastases of osteogenic sarcoma. Clin Nucl Med 1990;15:346-7.
  • 9 Roller LA, Chebib I, Bredella MA, Chang CY. Clinical, radiological, and pathological features of extraskeletal osteosarcoma. Skeletal Radiol 2018;47:1213-20.
  • 10 Murphey MD, Robbin MR, McRae GA, Flemming DJ, Temple HT, Kransdorf MJ. The many faces of osteosarcoma. Radiographics 1997;17:1205-31.