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CC BY-NC-ND 4.0 · World J Nucl Med 2020; 19(04): 432-434
DOI: 10.4103/wjnm.WJNM_60_19
Case Report

Mucinous urachal adenocarcinoma: A potential nonfluorodeoxyglucose-avid pitfall on 18fluorine-fluorodeoxyglucose positron emission tomography/computed tomography

Jeeban Das
1   Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, USA
2   Department of Radiology, Weill Cornell Medical College, New York, USA
,
Hebert Vargas
1   Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, USA
2   Department of Radiology, Weill Cornell Medical College, New York, USA
,
Gary Ulaner
1   Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, USA
2   Department of Radiology, Weill Cornell Medical College, New York, USA
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Abstract

Mucinous adenocarcinoma of the urachal remnant is a nonurothelial malignancy that may be asymptomatic until locally advanced or metastatic. We describe a 37-year-old woman with invasive ductal breast carcinoma who underwent 18Fluorine-fluorodeoxyglucose (18F-FDG) positron emission tomography (PET) computed tomography (CT) demonstrating a non-FDG avid pelvic mass, initially suspected to represent a pedunculated uterine fibroid. Magnetic resonance imaging revealed a mixed solid-cystic mass separate from the uterus, suspicious for urachal neoplasm, confirmed as mucinous adenocarcinoma on histopathology. Urachal tumors may not be FDG-avid and represent a potential pitfall on FDG PET/CT.

Keywords

18Fluorine-fluorodeoxyglucose - mucinous neoplasm - positron emission tomography/computed tomography - urachal adenocarcinoma

Financial support and sponsorship

This research was in part funded through the NIH/NCI Cancer Center Support Grant P30 CA008748.




Publication History

Received: 26 July 2019

Accepted: 25 October 2019

Article published online:
19 April 2022

© 2020. Sociedade Brasileira de Neurocirurgia. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commecial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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  • References

  • 1 Niedworok C, Panitz M, Szarvas T, Reis H, Reis AC, Szendröi A, et al. Urachal carcinoma of the bladder: Impact of clinical and immunohistochemical parameters on prognosis. J Urol 2016;195:1690-6.
  • 2 Ashley RA, Inman BA, Sebo TJ, Leibovich BC, Blute ML, Kwon ED, et al. Urachal carcinoma: Clinicopathologic features and long-term outcomes of an aggressive malignancy. Cancer 2006;107:712-20.
  • 3 Dhillon J, Liang Y, Kamat AM, Siefker-Radtke A, Dinney CP, Czerniak B, et al. Urachal carcinoma: A pathologic and clinical study of 46 cases. Hum Pathol 2015;46:1808-14.
  • 4 Yu JS, Kim KW, Lee HJ, Lee YJ, Yoon CS, Kim MJ, et al. Urachal remnant diseases: Spectrum of CT and US findings. Radiographics 2001;21:451-61.
  • 5 Parada Villavicencio C, Adam SZ, Nikolaidis P, Yaghmai V, Miller FH. Imaging of the urachus: Anomalies, complications, and mimics. Radiographics 2016;36:2049-63.
  • 6 Guimarães MD, Bitencourt AG, Lima EN, Marchiori E. 18FDG PET/CT findings in the unusual urachal adenocarcinoma. Clin Nucl Med 2014;39:831-4.
  • 7 Li X, Liu S, Yao S, Wang M. A rare case of urachal mucinous adenocarcinoma detected by 18F-FDG PET/CT. Clin Nucl Med 2015;40:282-5.
  • 8 Yang G, Wang Z, Liu S, Wu F, Li D. A rare case of urachal carcinoma metastatic to thoracic vertebra detected by FDG PET/CT. Clin Nucl Med 2017;42:544-6.
  • 9 Berger KL, Nicholson SA, Dehdashti F, Siegel BA. FDG PET evaluation of mucinous neoplasms: Correlation of FDG uptake with histopathologic features. AJR Am J Roentgenol 2000;174:1005-8.
  • 10 Lakhani A, Khan SR, Bharwani N, Stewart V, Rockall AG, Khan S, et al. FDG PET/CT pitfalls in gynecologic and genitourinary oncologic imaging. Radiographics 2017;37:577-94.