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CC BY-NC-ND 4.0 · World J Nucl Med 2020; 19(03): 291-295
DOI: 10.4103/wjnm.WJNM_83_19
Case Report

Solitary metastatic deposit in the mandible from follicular thyroid carcinoma

Nevena Manevska
Institute of Pathophysiology and Nuclear Medicine, Acad Isak S. Tadzer, Medical Faculty, University of Ss Cyril and Methodius, Skopje, Macedonia
,
Tanja Makazlieva
Institute of Pathophysiology and Nuclear Medicine, Acad Isak S. Tadzer, Medical Faculty, University of Ss Cyril and Methodius, Skopje, Macedonia
,
Sinisa Stojanoski
Institute of Pathophysiology and Nuclear Medicine, Acad Isak S. Tadzer, Medical Faculty, University of Ss Cyril and Methodius, Skopje, Macedonia
,
Ilir Vela
1   Clinic for Thoracic and Vascular Surgery, Medical Faculty, University of Ss Cyril and Methodius, Skopje, Macedonia
,
Selim Komina
2   Institute of Pathology, Medical faculty, University of Ss Cyril and Methodius, Skopje, Macedonia
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Abstract

Follicular thyroid carcinoma (FTC) is the second most common cancer of the thyroid, after papillary carcinoma. Oral metastasis arising from FTC is very rare. Mandible is more commonly affected than maxilla, with the premolar—molar region being the most frequent site of metastasis. We present the case of a 68yearold female, with swelling in the region of the parotid gland, complaining of periodic rightsided pain in the temporomandibular joint, which occurred most often in the morning with numbness and pain, and difficulty in opening the mouth. After ultrasound and X-ray, the patient was operated and the pathohistological finding was in favor of metastasis of FTC. After 3 months, a total thyroidectomy was performed, and FTC was detected in the right thyroid lobe. Laboratory results were as follows: FT4 = 9.92 pmol/L, thyroid-stimulating hormone = 9.9 mIU/L, and hTG >300 μg/L. Bone scan showed no bone metastasis. Radioablation with 131I of 150 mCi was given to the patient, followed by substitutional therapy with levothyroxine. Mandible metastasis as a single skeletal deposit from follicular thyroid carcinomas is a rare clinical finding. Maxillofacial surgeons should consider and rule out thyroid pathology before performing operation of tumor formation in the mandible region. If feasible, surgical-based treatment options offer the best survival outcomes.

Keywords

Follicular thyroid carcinoma - mandible metastasis - radioiodine

Financial support and sponsorship

Nil.




Publikationsverlauf

Eingereicht: 08. November 2019

Angenommen: 29. Januar 2020

Artikel online veröffentlicht:
19. April 2022

© 2020. Sociedade Brasileira de Neurocirurgia. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commecial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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