Anwendungen des endogenen Thrombinpotenzials

Summary

An overview is given on the method and the applications of thrombin generation assays. Thrombin generation assays provide a tool which can be used to trace the entire thrombin formation and inactivation of a plasma sample. Therefore they are principally different from traditional global assays like PT and aPTT and promise new opportunities for the assessment of bleeding or thrombotic risks.

Zusammenfassung

Es wird ein Überblick über die Methode und die Anwendungen von Thrombingenerierungstesten gegeben.

Thrombingenerierungsteste stellen ein Werkzeug dar, mit dem die gesamte Thrombin-bildung und Inaktivierung einer Plasmaprobe verfolgt werden kann. Sie unterscheiden sich damit prinzipiell von den herkömmlichen globalen Testen wie PT und aPTT und versprechen neue Möglichkeiten bei der Einschätzung von Blutungs- oder Thromboserisiken.

Keywords

Thrombin generation - endogenous thrombin potential - ETP - thrombophilia - haemophilia - anticoagulation

Schlüsselwörter

Thrombingenerierung - endogenes Thrombinpotenzial - ETP - Hämophilie - Antikoagulation

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