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CC BY 4.0 · Brazilian Journal of Oncology 2019; 15: e-20190010
DOI: 10.5935/2526-8732.20190010
Case Report

Pulmonary Metastasis of a Prostate Adenocarcinoma within a Primary Lung Adenocarcinoma: A Tumor-totumor Metastasis Case Report

Metástase Pulmonar de um Adenocarcinoma da Próstata dentro de um Adenocarcinoma Pulmonar Primário: Relato de Caso de uma metástase de tumor-para-tumor

André Marcondes Braga Ribeiro
1   A.C.Camargo Cancer Center, Nuclear Medicine - São Paulo - SP - Brazil
,
Ana Luiza Tatarin Vivan
1   A.C.Camargo Cancer Center, Nuclear Medicine - São Paulo - SP - Brazil
,
Eduardo Nóbrega Pereira Lima
1   A.C.Camargo Cancer Center, Nuclear Medicine - São Paulo - SP - Brazil
,
Maria Nirvana da Cruz Formiga
2   A.C.Camargo Cancer Center, Clinical Oncology - São Paulo - SP - Brazil
,
Mauro Daniel Spina Donadio
2   A.C.Camargo Cancer Center, Clinical Oncology - São Paulo - SP - Brazil
,
Felipe D'Almeida Costa
3   A.C.Camargo Cancer Center, Pathology - São Paulo - SP - Brazil
› Author Affiliations Financial support: none to declare.
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ABSTRACT

Applications for68 Ga-PSMA PET-CT continue to expand beyond prostate cancer. The objective of this case report is to illustrate a rare phenomenon known as tumor-totumor metastasis in which precise histological diagnosis is an essential prerequisite for correct clinical management of patients. A 89-year-old man with prostate cancer underwent68 Ga-PSMA PET-CT study for rescreening after increasing prostate specific antigen (PSA), revealing abnormal uptake of the radioindicator in the prostate and bilateral lung nodules. A biopsy was performed on one of the left lung nodules and the results of the pathology examination revealed that the lesion consisted of metastatic prostatic adenocarcinoma within a primary lung adenocarcinoma.

RESUMO

As aplicações para o PET-CT com68 Ga-PSMA continuam a se expandir além do câncer de próstata. O objetivo deste relato de caso é ilustrar um fenômeno raro conhecido como metástase de tumor-para-tumor em que o diagnóstico histológico preciso é um pré-requisito essencial para o correto manejo clínico dos pacientes. Um homem de 89 anos com câncer de próstata foi submetido ao estudo de PET/CT com68 Ga-PSMA para reestadiamento após apresentar aumento do antígeno específico da próstata (PSA), revelando captação anormal do radioidicador na próstata e em nódulos pulmonares bilaterais. Uma biópsia foi realizada em um dos nódulos do pulmão esquerdo e os resultados do exame anatomopatológico revelaram que a lesão consistia em um adenocarcinoma prostático metastático dentro de um adenocarcinoma de pulmão primário.

Keywords:

Neoplasm Metastasis - PROSTATE - LUNG.

Descritores:

68 Ga-PSMA - Metástase de tumor-para-tumor - Câncer de próstata - Câncer de pulmão.

AUTHOR'S CONTRIBUTION

André Marcondes Braga Ribeiro: Collection and assembly of data, Conception and design, Data analysis and interpretation, Final approval of manuscript, Manuscript writing.

Ana Luiza Tatarin Vivan: Conception and design, Data analysis and interpretation, Final approval of manuscript, Manuscript writing.

Eduardo Nóbrega Pereira Lima: Collection and assembly of data, Conception and design, Data analysis and interpretation.

Maria Nirvana da Cruz Formiga: Data analysis and interpretation, Final approval of manuscript, Manuscript writing.

Felipe D'Almeida Costa: Collection and assembly of data, Data analysis and interpretation, Final approval of manuscript.




Publication History

Received: 04 April 2019

Accepted: 24 April 2019

Article published online:
30 May 2019

© 2022. This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Bibliographical Record
André Marcondes Braga Ribeiro, Ana Luiza Tatarin Vivan, Eduardo Nóbrega Pereira Lima, Maria Nirvana da Cruz Formiga, Mauro Daniel Spina Donadio, Felipe D'Almeida Costa. Pulmonary Metastasis of a Prostate Adenocarcinoma within a Primary Lung Adenocarcinoma: A Tumor-totumor Metastasis Case Report. Brazilian Journal of Oncology 2019; 15: e-20190010.
DOI: 10.5935/2526-8732.20190010
 

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