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CC BY 4.0 · Brazilian Journal of Oncology 2019; 15: e-20190013
DOI: 10.5935/2526-8732.20190013
Case Report

Primary small cell carcinoma of the thyroid: a case report

Carcinoma de pequenas células primário da tireoide: relato de caso

Maria Clara Martins Prado
1   Hospital Felicio Rocho, Clinical Oncology - Belo Horizonte - Minas Gerais - Brazil
2   Fundação Educacional Lucas Machado (FELUMA), Pós-Graduação Ciências Médicas de Minas Gerais (PGCM- MG) - Belo Horizonte - Minas Gerais - Brazil
,
Isabella Rocha França Longo Staino
1   Hospital Felicio Rocho, Clinical Oncology - Belo Horizonte - Minas Gerais - Brazil
2   Fundação Educacional Lucas Machado (FELUMA), Pós-Graduação Ciências Médicas de Minas Gerais (PGCM- MG) - Belo Horizonte - Minas Gerais - Brazil
,
Hannah Damasceno Barreto da Silva
3   Hospital Felicio Rocho, Head and Neck Surgery - Belo Horizonte - Minas Gerais - Brazil
,
Alexandre Fonseca de Castro
1   Hospital Felicio Rocho, Clinical Oncology - Belo Horizonte - Minas Gerais - Brazil
4   ONCOMED - Center for treatment and prevention of neoplastic diseases, Clinical Oncology - Belo Horizonte - Minas Gerais - Brazil
,
Lysio França
3   Hospital Felicio Rocho, Head and Neck Surgery - Belo Horizonte - Minas Gerais - Brazil
,
Paula Ferreira Barros
5   Santa Casa de Misericordia, Pathology - Belo Horizonte - Minas Gerais - Brazil
› Author Affiliations Financial support: none to declare.
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ABSTRACT

The diagnosis of cervical mass is a challenge due to the wide variety of benign and malignant etiologies. Extrapulmonary small cell carcinomas (EPSCC) are rare entities, and those tumours arising as a primary cervical, especially in the thyroid gland, are exceedingly rare. As others small cell neuroendocrine carcinomas, the disease has an aggressive behavior. This case report is about a 40-years-old female patient admitted to the Hospital Felício Rocho, with airway compression caused by a cervical mass originated in the thyroid gland. The data were extracted from the medical records and information provided by the attendants. We describe here the multidisciplinary approach used to treat the patient as well as her outcome. We also review the clinical and molecular aspects of this rare entity.

RESUMO

O diagnóstico de massa cervical é um desafio devido à ampla variedade de etiologias benignas e malignas. Os carcinomas de pequenas células extrapulmonares (CPCEP) são entidades raras e esses tumores que surgem como primários na região cervical são ainda mais raros, especialmente na glândula tireoide. Assim como outros carcinomas de pequenas células neuroendócrinos, a doença apresenta comportamento agressivo. Esse relato de caso é sobre uma paciente mulher de 40 anos, internada no Hospital Felício Rocho, com compressão das vias aéreas causada por uma massa cervical originada na glândula tireoide. Os dados foram extraídos dos prontuários e informações fornecidas pelos assistentes. Descrevemos aqui a abordagem multidisciplinar usada para tratar a paciente, bem como o seu resultado. Também revisamos os aspectos clínicos e moleculares dessa rara entidade.

Keywords:

Carcinoma - Neuroendocrine tumors - Thyroid gland - Molecular biology - Diagnosis - Differential.

Descritores:

Carcinoma - Tumores neuroendócrinos - Glândula tireoide - Biologia Molecular - Diagnóstico - Diferencial.

AUTHOR'S CONTRIBUTION

Maria Clara Martins Prado: Collection and assembly of data, Conception and design, Data analysis and interpretation, Final approval of manuscript, Manuscript writing, Provision of study materials or patient.

Isabella Rocha França Longo Staino: Collection and assembly of data, Conception and design, Data analysis and interpretation, Final approval of manuscript, Manuscript writing, Provision of study materials or patient.

Hannah Damasceno Barreto da Silva: Collection and assembly of data, Conception and design, Data analysis and interpretation, Final approval of manuscript, Manuscript writing, Provision of study materials or patient.

Alexandre Fonseca de Castro: Collection and assembly of data, Conception and design, Data analysis and interpretation, Final approval of manuscript, Manuscript writing, Provision of study materials or patient.

Lysio França: Collection and assembly of data, Conception and design, Data analysis and interpretation, Final approval of manuscript, Manuscript writing, Provision of study materials or patient.

Paula Ferreira Barros: Collection and assembly of data, Conception and design, Data analysis and interpretation, Final approval of manuscript, Manuscript writing, Provision of study materials or patient.




Publication History

Received: 28 August 2018

Accepted: 13 June 2019

Article published online:
01 August 2019

© 2022. This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Bibliographical Record
Maria Clara Martins Prado, Isabella Rocha França Longo Staino, Hannah Damasceno Barreto da Silva, Alexandre Fonseca de Castro, Lysio França, Paula Ferreira Barros. Primary small cell carcinoma of the thyroid: a case report. Brazilian Journal of Oncology 2019; 15: e-20190013.
DOI: 10.5935/2526-8732.20190013
 

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