Primary small cell carcinoma of the thyroid: a case report

ABSTRACT

The diagnosis of cervical mass is a challenge due to the wide variety of benign and malignant etiologies. Extrapulmonary small cell carcinomas (EPSCC) are rare entities, and those tumours arising as a primary cervical, especially in the thyroid gland, are exceedingly rare. As others small cell neuroendocrine carcinomas, the disease has an aggressive behavior. This case report is about a 40-years-old female patient admitted to the Hospital Felício Rocho, with airway compression caused by a cervical mass originated in the thyroid gland. The data were extracted from the medical records and information provided by the attendants. We describe here the multidisciplinary approach used to treat the patient as well as her outcome. We also review the clinical and molecular aspects of this rare entity.

RESUMO

O diagnóstico de massa cervical é um desafio devido à ampla variedade de etiologias benignas e malignas. Os carcinomas de pequenas células extrapulmonares (CPCEP) são entidades raras e esses tumores que surgem como primários na região cervical são ainda mais raros, especialmente na glândula tireoide. Assim como outros carcinomas de pequenas células neuroendócrinos, a doença apresenta comportamento agressivo. Esse relato de caso é sobre uma paciente mulher de 40 anos, internada no Hospital Felício Rocho, com compressão das vias aéreas causada por uma massa cervical originada na glândula tireoide. Os dados foram extraídos dos prontuários e informações fornecidas pelos assistentes. Descrevemos aqui a abordagem multidisciplinar usada para tratar a paciente, bem como o seu resultado. Também revisamos os aspectos clínicos e moleculares dessa rara entidade.

Keywords:

Carcinoma - Neuroendocrine tumors - Thyroid gland - Molecular biology - Diagnosis - Differential.

Descritores:

Carcinoma - Tumores neuroendócrinos - Glândula tireoide - Biologia Molecular - Diagnóstico - Diferencial.

AUTHOR'S CONTRIBUTION

Maria Clara Martins Prado: Collection and assembly of data, Conception and design, Data analysis and interpretation, Final approval of manuscript, Manuscript writing, Provision of study materials or patient.

Isabella Rocha França Longo Staino: Collection and assembly of data, Conception and design, Data analysis and interpretation, Final approval of manuscript, Manuscript writing, Provision of study materials or patient.

Hannah Damasceno Barreto da Silva: Collection and assembly of data, Conception and design, Data analysis and interpretation, Final approval of manuscript, Manuscript writing, Provision of study materials or patient.

Alexandre Fonseca de Castro: Collection and assembly of data, Conception and design, Data analysis and interpretation, Final approval of manuscript, Manuscript writing, Provision of study materials or patient.

Lysio França: Collection and assembly of data, Conception and design, Data analysis and interpretation, Final approval of manuscript, Manuscript writing, Provision of study materials or patient.

Paula Ferreira Barros: Collection and assembly of data, Conception and design, Data analysis and interpretation, Final approval of manuscript, Manuscript writing, Provision of study materials or patient.

Publikationsverlauf

Eingereicht: 28. August 2018

Angenommen: 13. Juni 2019

Artikel online veröffentlicht:
01. August 2019

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