Download PDF
CC BY 4.0 · Brazilian Journal of Oncology 2021; 17: e-20200040
DOI: 10.5935/2526-8732.20200040
Case Report

Penile melanoma

Melanoma peniano

Luiz Felipe de Mello Pereira Leitão
1   Irmandade Santa Casa de Misericórdia de São Paulo, Urology - Sao Paulo, - Brazil
,
Fernanda Monteiro Orellana
1   Irmandade Santa Casa de Misericórdia de São Paulo, Urology - Sao Paulo, - Brazil
,
João Pedro Vaz de Souza Cabral Simões
1   Irmandade Santa Casa de Misericórdia de São Paulo, Urology - Sao Paulo, - Brazil
,
Rute Facchini Lellis
2   Irmandade Santa Casa de Misericórdia de São Paulo, Pathology - Sao Paulo, Sao Paulo, Brazil
,
Marcus Maia
3   Irmandade Santa Casa de Misericórdia de São Paulo, Dermatology - Sao Paulo, Sao Paulo, Brazil
,
Roni de Carvalho Fernandes
1   Irmandade Santa Casa de Misericórdia de São Paulo, Urology - Sao Paulo, - Brazil
,
Luis Gustavo Morato de Toledo
1   Irmandade Santa Casa de Misericórdia de São Paulo, Urology - Sao Paulo, - Brazil
› Author Affiliations Financial support: none to declare.
› Further Information
   Permissions and Reprints All articles of this category

ABSTRACT

Penile melanoma is a rare event, responsible for less than 1.4% of penile cancers. In general, it is late diagnosed and the treatment is usually aggressive. The authors present a 66-year-old Caucasian man who had an ulcerated penile lesion for 1 year, diagnosed as melanoma after biopsy and treated as locally advanced disease with partial penectomy, identification of the sentinel lymph node and bilateral inguinal lymphadenectomy.

RESUMO

O melanoma peniano é um evento raro, responsável por menos de 1,4% dos cânceres penianos. No geral, o diagnóstico é tardio e o tratamento costuma ser agressivo. Os autores apresentam um homem de 66 anos de idade, caucasiano, com lesão peniana ulcerada há 1 ano, diagnosticada como melanoma após biópsia e tratada como doença localmente avançada com penectomia parcial, identificação do linfonodo sentinela e linfadenectomia inguinal bilateral.

Keywords:

Melanoma - Penis - Penile neoplasms - Surgical treatment - Penectomy - Sentinel lymph node.

Descritores:

Melanoma - Pênis - Neoplasias penianas - Tratamento cirúrgico - Penectomia - Linfonodo sentinela.


Publication History

Received: 09 July 2020

Accepted: 28 October 2020

Article published online:
18 January 2021

© 2022. This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Thieme Revinter Publicações Ltda.
Rua do Matoso 170, Rio de Janeiro, RJ, CEP 20270-135, Brazil

Bibliographical Record
Luiz Felipe de Mello Pereira Leitão, Fernanda Monteiro Orellana, João Pedro Vaz de Souza Cabral Simões, Rute Facchini Lellis, Marcus Maia, Roni de Carvalho Fernandes, Luis Gustavo Morato de Toledo. Penile melanoma. Brazilian Journal of Oncology 2021; 17: e-20200040.
DOI: 10.5935/2526-8732.20200040
 

  • REFERENCES

  • Baraziol R, Schiavon M, Fraccalanza E, De Giorgi G.. Melanoma in situ of penis. Medicine 2017; Sep; 96 (36) e7652.W
    Search in Google Scholar
  • Oldbring J, Mikulowski P.. Malignant melanoma of the penis and male urethra: report of nine cases and review of the literature. Cancer 1987; Feb; 59 (03) 581-587
    Search in Google Scholar
  • Bechara GR, Schwindt ABS, Ornellas AA, Silva DEA, Lott FM, Campos FS.. Penile primary melanoma: analysis of 6 patients treated at Brazilian national cancer institute in the last eight years. Int Braz J Urol 2013; Dec; 39 (06) 823-831
    Search in Google Scholar
  • Li Y, Yuan H, Wang A, Zhang Z, Wu J, Wei Q.. Malignant melanoma of the penis and urethra: one case report. World J Surg Oncol 2014; 12 (01) 340
    Search in Google Scholar
  • Van Geel AN, den Bakker MA, Kirkels W, Horenblas S, Kroon BBR, Wilt JHW. et al Prognosis of primary mucosal penile melanoma: a series of 19 Dutch patients and 47 patients from the literature. Urol 2007; Jul; 70 (01) 143-147
    Search in Google Scholar
  • Jabiles AG, Del Mar EY, Perez GAD, Vera FV, Montoya LM, Deza CMM.. Penile melanoma: a 20year analysis of six patients at the National Cancer Institute of Peru, Lima. Ecancer 2017; 11: 731
    Search in Google Scholar
  • Balch CM, Gershenwald JE, Soong SJ, Thompson JF, Atkins MB, Byrd DR. et al Final version of 2009 AJCC melanoma staging and classification. J Clin Oncol 2009; Dec; 27 (36) 6199-6206
    Search in Google Scholar
  • Miller E, Barnea Y, Karin E, Leshem D, Weiss J, Leider-Trejo L, Schneebaum S.. Sentinel lymph node biopsy in the diagnosis and treatment of multicentric malignant melanoma of the penis. Isr Med Assoc J 2009; Apr; 8 (04) 292-293
    Search in Google Scholar
  • Napolitano M, Annessi G, Didona D, Didona B.. Multifocal melanoma in situ of the penis treated with topical Imiquimod. J Eur Acad Dermatol Venereol 2016; Mar; 30 (03) 458-460
    Search in Google Scholar
  • Yang A, Klapman M, Cassarino DS.. Spontaneously regressing primary nodular melanoma of the glans penis. Cutis 2014; Oct; 94 (04) E9-E11
    Search in Google Scholar
  • Napolitano M, Annessi G, Didona D, Didona B.. Multifocal melanoma in situ of the penis treated with topical Imiquimod. J Eur Acad Dermatol Venereol 2016; Mar; 30 (03) 458-460 https://doi.org/10.1111/jdv.12835
    Search in Google Scholar
  • Oxley JD, Corbishley C, Down L, Watkin N, Dickerson D, Wong NACS.. Clinicopathological and molecular study of penile melanoma. J Clin Pathol 2012; Mar; 65 (03) 228-231 https://doi.org/10.1136/jclinpath-2011-200344
    Search in Google Scholar