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DOI: 10.5935/2526-8732.20210005
Cutaneous Acceptability And Hydratation of Topical Products In Patients Undergoing Radiotherapy and Antineoplastic Treatment
Aceitabilidade cutânea e hidratação de produtos tópicos em pacientes submetidos a radioterapia e tratamento antineoplásico
Financial support: none to declare.
RESUMO
Background: New antineoplastic agents have increased the survival rate of cancer patients, however, the incidence of cutaneous skin toxicity, which leads to worsening in the quality of life and to the necessity of interrupting the treatment, continues presently. Natural agents, as Aloe vera and Calendula, have been suggested as potential ways of prevention and treatment for radiation dermatitis resulting from radiotherapy, providing better adhesion to the therapies and improving the wellbeing of the patients.
Purpose: To evaluate the cutaneous acceptability and hydrating effect of four topical test products in patients undergoing radiotherapy and antineoplastic treatment.
Methods: Both sex participants, undergoing oncological treatments, were included. Patients received a prescription to self-applied topical test products - A (Washcare), B (Moistcare), C (Extremecare) and D (Coolcare Mask) during 30 days. Products acceptability and skin hydration were evaluated considering the occurrence of skin adverse reaction, participants self-reported feelings of skin discomfort, dermatologist and instrumental skin hydration evaluation.
Results: Thirty-three participants initiated and completed the study. None of them had skin reactions or discomfort in the area of application, and no adverse events were reported. Twenty-five participants (75.8%) reported improvement in skin hydration after using the test products, while eight participants (24.2%) observed the maintenance of hydration (p<0,005).
Conclusion: The products evaluated showed improvement in skin condition in most patients, increased hydration and good skin acceptability in patients with skin toxicities caused by the cancer treatments.
AUTHOR'S CONTRIBUTION
Carlos D`App Santos Machado-Filho: Collection and assembly of data, Conception and design, Data analysis and interpretation, Final approval of manuscript, Manuscript writing, Provision of study materials or patient
Odimila Kawahata Adriano Silva: Collection and assembly of data, Final approval of manuscript, Manuscript writing, Provision of study materials or patient
Silvia Regina Lamas: Data analysis and interpretation, Final approval of manuscript, Manuscript writing, Provision of study materials or patient
Publication History
Received: 10 February 2019
Accepted: 29 May 2020
Article published online:
14 May 2021
© 2022. This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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Carlos D'App Santos Machado-Filho, Odimila Kawahata Adriano Silva, Silvia Regina Lamas. Cutaneous Acceptability And Hydratation of Topical Products In Patients Undergoing Radiotherapy and Antineoplastic Treatment. Brazilian Journal of Oncology 2021; 17: e-20210005.
DOI: 10.5935/2526-8732.20210005
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