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CC BY 4.0 · Brazilian Journal of Oncology 2021; 17: e-20210009
DOI: 10.5935/2526-8732.20210009
Case Report
Oncological Surgery

Chronic renal failure as initial presentation of pelvic hemangioendothelioma.

Insuficiência renal crônica como manifestação inicial de hemangioendotelioma pélvico.

João Gabriel Léda Braga 
1   Santa Casa de Misericórdia de São Paulo, General Surgery, São Paulo, São Paulo, Brazil
,
Fernanda Monteiro Orellana 
2   Santa Casa de Misericórdia de São Paulo, Urology - São Paulo, São Paulo, Brazil
,
Alan Ziroldo 
3   Santa Casa de São Paulo School of Medical Sciences, Medicine, São Paulo, São Paulo, Brazil
,
Leonardo Sementilli 
4   Santa Casa de Misericórdia de São Paulo, Pathology - São Paulo - São Paulo - Brazil
,
Luis Gustavo Morato De Toledo 
2   Santa Casa de Misericórdia de São Paulo, Urology - São Paulo, São Paulo, Brazil
,
Roni de Carvalho Fernandes 
2   Santa Casa de Misericórdia de São Paulo, Urology - São Paulo, São Paulo, Brazil
› Author Affiliations Financial support: none to declare.
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ABSTRACT

Hemangioendothelioma is a rare vascular tumor whose etiology has not yet been defined. Currently, it is known to affect different sites, such as the abdominal-pelvic cavity. It is also known to present intermediate characteristics to hemangioma and angiosarcoma. In recent studies, 50-76% of patients are asymptomatic. Surgical treatment is indicated in most cases. The authors present a case of hemangioendothelioma with pelvic involvement and initial presentation as acute renal failure due to extrinsic ureteral compression, treated surgically, with histopathological diagnosis of hemangioendothelioma and recurrence after one year of the initial treatment presenting a histologically different form. This case illustrates a rare cause of lower urinary tract symptoms (LUTS), obstructive uropathy and acute renal failure and the appearance of two different tumors within a year, in line with the genetic/immunological factor in its genesis.

RESUMO

O hemangioendotelioma é um tumor vascular raro cuja etiologia ainda não foi definida. Atualmente, sabe-se que afeta diferentes locais, como a cavidade abdominal e pélvica. Sabe-se também que possui características intermediárias do hemangioma e do angiossarcoma. Em estudos recentes, 50-76% dos pacientes são assintomáticos. O tratamento cirúrgico é indicado na maioria dos casos. Os autores apresentam um caso de hemangioendotelioma com envolvimento pélvico e apresentação inicial como insuficiência renal aguda por compressão extrínseca ureteral, tratado cirurgicamente, diagnóstico histopatológico de hemangioendotelioma e recorrência após um ano do tratamento inicial, apresentando uma forma histologicamente diferente. Este caso ilustra uma causa rara de LUTS, uropatia obstrutiva e insuficiência renal aguda e o aparecimento de dois tumores diferentes dentro de um ano, em consonância com o fator genético/imunológico em sua gênese.

Keywords:

Hemangioendothelioma - Sarcoma - Myxoid liposarcoma - Chronic renal failure..

Descritores:

Hemangioendotelioma - Sarcoma - Lipossarcoma mixóide - Insuficiência renal crônica.


Publication History

Received: 14 June 2020

Accepted: 13 January 2021

Article published online:
05 March 2021

© 2022. This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Bibliographical Record
João Gabriel Léda Braga, Fernanda Monteiro Orellana, Alan Ziroldo, Leonardo Sementilli, Luis Gustavo Morato De Toledo, Roni de Carvalho Fernandes. Chronic renal failure as initial presentation of pelvic hemangioendothelioma.. Brazilian Journal of Oncology 2021; 17: e-20210009.
DOI: 10.5935/2526-8732.20210009
 

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