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CC BY 4.0 · Brazilian Journal of Oncology 2021; 17: e-20210029
DOI: 10.5935/2526-8732.20210029
Case Report
Clinical Oncology

Malignant giant cell tumor of the uterus: a case report

Tumor maligno de células gigantes do útero: um relato de caso
Rivadávio Antunes Menacho de Oliveira
1   Londrina Cancer Hospital, Clinical Oncology - Londrina - Paraná - Brazil
,
Carlos Eduardo Stecca
1   Londrina Cancer Hospital, Clinical Oncology - Londrina - Paraná - Brazil
,
Tassiara Silva
1   Londrina Cancer Hospital, Clinical Oncology - Londrina - Paraná - Brazil
,
Mariana Miyasaki Piovesana
1   Londrina Cancer Hospital, Clinical Oncology - Londrina - Paraná - Brazil
,
Veruska Peron
1   Londrina Cancer Hospital, Clinical Oncology - Londrina - Paraná - Brazil
,
Angela Gordan
2   Londrina Cancer Hospital, Pathologic Anatomy - Londrina - Paraná - Brazil
› Author Affiliations Financial support: None to declare.
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ABSTRACT

This report describes a rare case of malignant extraosseous giant cell tumor (GCT). It refers to a patient with an initial diagnosis of a locally advanced malignant GCT of the uterus, with disease progression to lung and mediastinum seven months after the diagnosis, requiring first line treatment with chemotherapy. Extraosseous presentation of GCT with early distant dissemination is unusual and the role of systemic cytotoxic treatment remains unclear.

RESUMO

O presente relato descreve uma apresentação clínica rara de um tumor de células gigantes (TCG). O caso relatado se refere a uma paciente portadora de um TCG uterino maligno localmente avançado que evoluiu com metástase pulmonar e mediastinal sete meses após o diagnóstico, necessitando de primeira linha de tratamento com quimioterapia. TCG extraósseo, especialmente quando associado a comportamento agressivo e disseminação à distância precoce e altamente infrequente, e o papel do tratamento sistêmico citotóxico permanece incerto.

Keywords:

Giant cell tumor - Uterine - Uterus.

Descritores:

Tumor de células gigantes - Uterino - Útero.


Publication History

Received: 20 October 2020

Accepted: 13 August 2021

Article published online:
24 September 2021

© 2021. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution 4.0 International License, permitting copying and reproduction so long as the original work is given appropriate credit (https://creativecommons.org/licenses/by/4.0/)

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Bibliographical Record
Rivadávio Antunes Menacho de Oliveira, Carlos Eduardo Stecca, Tassiara Silva, Mariana Miyasaki Piovesana, Veruska Peron, Angela Gordan. Malignant giant cell tumor of the uterus: a case report. Brazilian Journal of Oncology 2021; 17: e-20210029.
DOI: 10.5935/2526-8732.20210029
 

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