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CC BY 4.0 · Brazilian Journal of Oncology 2022; 18: e-20220309
DOI: 10.5935/2526-8732.20220309
Case Report
Surgical Oncology

Uterine rupture secondary to undiagnosed placental site trophoblastic tumor: case report

Karin Hoch
1   University of campinas, Department of Obstetrics and Gynecology - Campinas - SP - Brazil
,
Arthur Antolini Tavares
1   University of campinas, Department of Obstetrics and Gynecology - Campinas - SP - Brazil
,
Cristina Laguna Benetti-pinto
1   University of campinas, Department of Obstetrics and Gynecology - Campinas - SP - Brazil
,
Daniela Angerame Yela 
1   University of campinas, Department of Obstetrics and Gynecology - Campinas - SP - Brazil
› Institutsangaben Financial support: None to declare.
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ABSTRACT

Placental site trophoblastic tumor is a rare and malignant form of gestational trophoblastic disease. Its incidence rate is 1/50.000-100.000 pregnancies and accounts for less than 3% of all cases of gestational trophoblastic disease. In addition to its infrequency, the tumor lacks pathognomonic sonographic features, delaying diagnosis until immunohistochemical staining of uterine samples. Early diagnosis is key to avoid metastatic disease. We report a case of an undiagnosed placental site trophoblastic tumor, which caused uterine rupture and hemorrhagic shock.

Keywords:

immunohistochemistry - placental site trophoblastic tumor - transvaginal sonography


Publikationsverlauf

Eingereicht: 27. Oktober 2021

Angenommen: 30. November 2021

Artikel online veröffentlicht:
13. September 2022

© 2022. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution 4.0 International License, permitting copying and reproduction so long as the original work is given appropriate credit (https://creativecommons.org/licenses/by/4.0/)

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Bibliographical Record
Karin Hoch, Arthur Antolini Tavares, Cristina Laguna Benetti-pinto, Daniela Angerame Yela. Uterine rupture secondary to undiagnosed placental site trophoblastic tumor: case report. Brazilian Journal of Oncology 2022; 18: e-20220309.
DOI: 10.5935/2526-8732.20220309
 

  • REFERENCES

  • 1 Lucas R, Cunha T M, Santos F B. Placental site trophoblastic tumor: a case report and review of the literature. J Radiol Case Rep 2015; 9 (04) 14-22
    Suche in Google Scholar
  • 2 Brown J, Naumann R W, Seckl M J, Schink J. 15 years of progress in gestational trophoblastic disease: scoring, standardization, and salvage. Gynecol Oncol 2016; 144 (01) 200-207
    Suche in Google Scholar
  • 3 De Nola R, Schönauer L M, Fiore M G, Loverro M, Carriero C, Di Naro E. Management of placental site trophoblastic tumor: two case reports. Medicine (Baltimore) 2018; 97 (48) 134-139
    Suche in Google Scholar
  • 4 Gadducci A, Carinelli S, Guerrieri M E, Aletti G D. Placental site trophoblastic tumor and epithelioid trophoblastic tumor: clinical and pathological features.
  • 5 Gynecol Oncol 2019; 153 (07) 684-693
  • 6 Braga A, Sun SY, Maestá I, Uberti E. Doença trofoblástica gestacional. São Paulo: Federação Brasileira das Associações de Ginecologia e Obstetrícia (FEBRASGO); 2018. (Protocolo FEBRASGO - Obstetrícia, no 23/ Comissão Nacional Especializada em Doença Trofoblástica Gestacional).
    Suche in Google Scholar
  • 7 Shaaban AM, Rezvani M, Haroun RR, Kennedy AM, Elsayes KM, Olpin JD, Salama ME, Foster BR, Menias CO. Gestational Trophoblastic Disease: Clinical and Imaging Features. RadioGraphics 2017; 37 (04) 681-700
    Suche in Google Scholar
  • 8 Feng X, Wei Z, Zhang S, Du Y, Zhao H. A Review on the Pathogenesis and Clinical Management of Placental Site Trophoblastic Tumors. Front Oncol 2019; 9: 937-937
    Suche in Google Scholar
  • 9 Santoro G, Laganà A.S, Micali A. et al. Historical, morphological and clinical overview of placental site trophoblastic tumors: from bench to bedside. Arch Gynecol Obstet 2017; 295: 173-187
    Suche in Google Scholar
  • 10 Behtash N, Ghaemmaghami F, Hasanzadeh M. Long term remission of metastatic placental site trophoblastic tumor (PSTT): Case report and review of literature. World J Surg Onc 2005; 3: 34-34
    Suche in Google Scholar
  • 11 Zhou Y, Lu H, Yu C, Tian Q, Lu W. Sonographic characteristics of placental site trophoblastic tumor. Ultrasound Obstet Gynecol 2012; 41 (06) 679-684
    Suche in Google Scholar
  • 12 Ngan HYS, Secki MJ, Berkowitz RS. et al. Diagnosis and management of gestational trophoblastic disease: 2021 update. Int J Gynecol Obstet 2021; 155 (Suppl. 1) 86-93
    Suche in Google Scholar
  • 13 Hancock BW, Tidy J. Placental site trophoblastic tumour and epithelioid trophoblastic tumour. Best Pract Res Clin Obstet Gynaecol 2021; 74: 131-148
    Suche in Google Scholar
  • 14 Chaves M, Maia T, Cunha TM, Veiga VF. Placental site trophoblastic tumour: the rarest subtype of gestational trophoblastic disease. BMJ Case Rep 2020; 13 (10) e235756
    Suche in Google Scholar
  • 15 Rey Valzacchi GM, Odetto D, Chacon CB, Wernicke A, Xiang Y. Placental site trophoblastic disease. Int J Gynecol Cancer 2020; 30 (01) 144-149
    Suche in Google Scholar
  • 16 Luiza J W, Taylor S E, Gao F F, Edwards R P. Placental site trophoblastic tumor: Immunohistochemistry algorithm key to diagnosis and review of literature. Gynecol Oncol Case Rep 2013; 7: 13-15
    Suche in Google Scholar
  • 17 Shih IM, Kurman RJ. Ki-67 labeling index in the differential diagnosis of exaggerated placental site, placental site trophoblastic tumor, and choriocarcinoma: a double immunohistochemical staining technique using Ki-67 and Mel-CAM antibodies. Hum Pathol 1998; 29 (01) 27-33
    Suche in Google Scholar