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DOI: 10.5935/2526-8732.20220316
Cross-sectional study of 1-to-5- year head and neck cancer survivors
Estudo transversal de sobreviventes de 1 a 5 anos de câncer de cabeça e pescoçoThis research was financed by the funds FAPESP (#13/03351-9) and CAPES (#001).
ABSTRACT
Objectives: This study aimed to determine the demographic and clinical profile of 1-to-5year head and neck cancer (HNC) survivors, and they oral features that could affect QoL.
Material and Methods: In this cross-sectional study, medical records of 184 were reviewed concerning demographic, clinical and tumour characteristics. 40 of them underwent a quality of life (QoL) questionnaire and assessment of xerostomia (XA), using the oral health impact profile -14 (OHIP-14) and the xerostomia inventory (XI). Salivary flow was determined by measurement of stimulated whole salivary flow rate (SWSFR) and the number of teeth (NT) by determining the number of extracted and/or lost teeth. One-sample t-test, absolute and relative frequencies and Spearman's correlation test was used for statistical analysis of data.
Results: Most HNC patients were male, aged between 50 and 60 years, alcohol and tobacco users, with low educational attainment, several comorbidities, and pharyngeal tumours. The high scores in the OHIP-14 (23.82±14.0) and XI (39.2±7.6) indicated that most patients had their QoL adversely affected and had xerostomia. Mean SWSFR was 0.2mL/ min, and 15% (n=28) of patients were edentulous. The Spearman test showed a significant correlation between QoL and xerostomia, and salivary flow and QoL.
Conclusion: This study evaluated characteristics of head and neck cancers (HNC) concerning demographic, clinical and tumour characteristics, quality of life (QoL), xerostomia, salivary flow, and number of teeth (NT) through an observational and cross-sectional study.
RESUMO
Objetivos: Este estudo teve como objetivo determinar o perfil demográfico e clínico de sobreviventes de 1 a 5 anos de câncer de cabeça e pescoço (CCP) e as características bucais que podem afetar a QV.
Material e Métodos: Neste estudo transversal, foram revisados prontuários de 184 prontuários quanto às características demográficas, clínicas e tumorais. 40 deles foram submetidos a um questionário de qualidade de vida (QV) e avaliação de xerostomia (XA), usando o perfil de impacto na saúde bucal -14 (OHIP-14) e o inventário de xerostomia (XI). O fluxo salivar foi determinado pela medição da taxa de fluxo salivar total estimulado (MTFSTE) e o número de dentes (NT) pela determinação do número de dentes extraídos e/ou perdidos. O teste-t para uma amostra, frequências absolutas e relativas e o teste de correlação de Spearman foram utilizados para análise estatística dos dados.
Resultados: A maioria dos pacientes com CCP era do sexo masculino, com idade entre 50 e 60 anos, usuários de álcool e tabaco, com baixa escolaridade, várias comorbidades e tumores de faringe. Os altos escores no OHIP-14 (23,82±14,0) e XI (39,2±7,6) indicaram que a maioria dos pacientes teve sua QV prejudicada e apresentou xerostomia. A média do SWSFR foi de 0,2mL/min e 15% (n=28) dos pacientes eram desdentados. O teste de Spearman mostrou correlação significativa entre QV e xerostomia, e fluxo salivar e QV.
Conclusão: Este estudo avaliou características dos cânceres de cabeça e pescoço (CCP) quanto às características demográficas, clínicas e tumorais, qualidade de vida (QV), xerostomia, fluxo salivar e número de dentes (NT) por meio de um estudo observacional e transversal.
Funding
This research was financed by the funds FAPESP (#13/03351-9) and CAPES (#001).
Regulatory statement:
This study was approved by the institutional review board of the institutions (CAAE 27765714.0.000.5419).
Author's Contribution:
Conception and design, Data analysis and interpretation, Final approval of manuscript, Manuscript writing, Provision of study materials or patient
Publication History
Received: 08 November 2021
Accepted: 17 December 2021
Article published online:
18 February 2022
© 2022. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution 4.0 International License, permitting copying and reproduction so long as the original work is given appropriate credit (https://creativecommons.org/licenses/by/4.0/)
Thieme Revinter Publicações Ltda.
Rua do Matoso 170, Rio de Janeiro, RJ, CEP 20270-135, Brazil
Pedro Bastos Cruvinel, Raony Molim de Sousa Pereira, André Luiz de Macedo Fressatti, Bianka Jurca Gonçalves-da Motta, Ana Carolina Fragoso Motta, Harley Francisco de Oliveira, Hilton Marcos Alves Ricz, Leandro Dorigan de Macedo, Camila Tirapelli. Cross-sectional study of 1-to-5- year head and neck cancer survivors. Brazilian Journal of Oncology 2022; 18: e-20220316.
DOI: 10.5935/2526-8732.20220316
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