Download PDF
CC BY 4.0 · Brazilian Journal of Oncology 2023; 19: e-20230399
DOI: 10.5935/2526-8732.20230399
Case Report
Surgical Oncology

Stewart-Treves syndrome: a case report

Síndrome de Stewart-Treves: relato de caso
Eloisa Fritsche 
1   Unidavi - Centro Universitário para o Desenvolvimento do Alto Vale do Itajaí, Medical School, Rio do Sul - Santa Catarina, Brazil
,
Eduarda Fritsche
1   Unidavi - Centro Universitário para o Desenvolvimento do Alto Vale do Itajaí, Medical School, Rio do Sul - Santa Catarina, Brazil
,
Lucio Flavo Dalri
1   Unidavi - Centro Universitário para o Desenvolvimento do Alto Vale do Itajaí, Medical School, Rio do Sul - Santa Catarina, Brazil
,
Lais Cristine Nienkotter
1   Unidavi - Centro Universitário para o Desenvolvimento do Alto Vale do Itajaí, Medical School, Rio do Sul - Santa Catarina, Brazil
› Author Affiliations Financial support: No.
› Further Information
   Permissions and Reprints All articles of this category

ABSTRACT

Stewart-Treves syndrome is a very rare lymphangiosarcoma with a poor prognosis. It usually develops in female patients after mastectomy with axillary lymph node dissection and is associated with chronic lymphedema. Stewart-Treves angiosarcoma is described in less than 1% of all soft tissue sarcomas, of which 0.5% occur in radically mastectomized patients. The case reported below describes the diagnosis and treatment of Stewart-Treves syndrome, with an initial clinical presentation of cutaneous lesions characteristic of the syndrome, manifesting ipsilaterally 22 years after quadrantectomy and radical right lymphadenectomy with adjuvant radiotherapy, the reported patient achieved, extraordinarily, a 12-year survival, far beyond the cases published to date.

RESUMO

A síndrome de Stewart-Treves é um linfangiossarcoma muito raro com prognóstico ruim. Geralmente se desenvolve em pacientes do sexo feminino após mastectomia com dissecção linfonodal axilar e está associada à linfedema crônico. O angiossarcoma de Stewart-Treves é descrito em menos de 1% de todos os sarcomas de tecidos moles, dos quais 0,5% ocorrem em pacientes radicalmente mastectomizadas. O caso relatado a seguir descreve o diagnóstico e tratamento da síndrome de Stewart-Treves, com apresentação clínica inicial de lesões cutâneas características da síndrome, manifestando-se ipsilateralmente 22 anos após quadrantectomia e linfadenectomia radical direita com radioterapia adjuvante, o paciente relatado alcançou, extraordinariamente, uma sobrevida de 12 anos, muito além dos casos publicados até o momento.

Keywords:

Lymphangiosarcoma - Survival - Breast neoplasms

Descritores:

Linfangiossarcoma - Sobrevivência - Neoplasias mamárias


Publication History

Received: 04 January 2023

Accepted: 13 March 2023

Article published online:
26 April 2023

© 2023. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution 4.0 International License, permitting copying and reproduction so long as the original work is given appropriate credit (https://creativecommons.org/licenses/by/4.0/)

Thieme Revinter Publicações Ltda.
Rua do Matoso 170, Rio de Janeiro, RJ, CEP 20270-135, Brazil

Bibliographical Record
Eloisa Fritsche, Eduarda Fritsche, Lucio Flavo Dalri, Lais Cristine Nienkotter. Stewart-Treves syndrome: a case report. Brazilian Journal of Oncology 2023; 19: e-20230399.
DOI: 10.5935/2526-8732.20230399
 

  • REFERENCES

  • 1 Wierzbicka-Hainaut E, Guillet G. Syndrome de Stewart-Treves (angiosarcome sur lymphœdème): complication rare du lymphųdème. Presse Med 2010; 39 (12) 1305-8
    Search in Google Scholar
  • 2 Wang LL, Cui LF, Gao Y, Jiang ZC. Clinicopathologic features of Stewart-Treves syndrome. Int J Clin Exp Pathol 2019; Mar 12 (03) 680-8
    Search in Google Scholar
  • 3 Pereira ESP, Moraes ET, Siqueira DM, Santos MAS. Stewart-Treves syndrome. An Bras Dermatol 2015; 90 3 Suppl 1 229-31
    Search in Google Scholar
  • 4 Mesli SN, Ghouali AK, Benamara F, Taleb FA, Tahraoui H, Abi-Ayad C. Stewart-Treves syndrome involving chronic lymphedema after mastectomy of breast cancer. Case Rep Surg 2017; 2017: 1-4
    Search in Google Scholar
  • 5 Sevil A, Aktas H, Ömer FE, Aktümen A, Erol H. Stewart Treves syndrome in a woman with mastectomy. J Clin Diagn Res 2016; 10 (02) WD1-WD2
    Search in Google Scholar
  • 6 Vieira LJ, Vieira JP, Oliveira AF, Freitas RR, Rabêlo FT, Mira RRL. et al. Tratamento cirúrgico de tumores malignos envolvendo ombro e membro superior: estudo de 10 casos. Rev Bras Cancerol 2004; 50 (02) 127-32
    Search in Google Scholar
  • 7 Moraes JA, Reis TJCC, Naspolini Filho H, Batista TP, Lucena MA. Amputação interescapulotorácica sob anestesia locorregional. Rev Col Bras Cir. 2013;40(5)
  • 8 Khatri VP. Atlas de técnicas avançadas em cirurgia [Internet]. Rio de Janeiro: Grupo GEN; 2014. [access in 2022 Jul 20]. Available from https://integrada.minhabiblioteca.com.br/#/books/9788595153950/
    Search in Google Scholar
  • 9 Esbeen LV, Rocket-Gravy PP. Improvement of Stewart-Treves angiosarcoma through interleukin 23p19 inhibition. JAAD Case Rep 2021; 17: 84-6
    Search in Google Scholar