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CC BY-NC 4.0 · Arch Plast Surg 2014; 41(06): 673-678
DOI: 10.5999/aps.2014.41.6.673
Original Article

Skin Thickness of the Anterior, Anteromedial, and Anterolateral Thigh: A Cadaveric Study for Split-Skin Graft Donor Sites

Jeffrey CY Chan
Department of Plastic and Reconstructive Surgery, Galway University Hospital, Galway, Ireland
,
John Ward
Department of Plastic and Reconstructive Surgery, Galway University Hospital, Galway, Ireland
,
Fabio Quondamatteo
Department of Anatomy, National University of Ireland, Galway, Ireland
,
Peter Dockery
Department of Anatomy, National University of Ireland, Galway, Ireland
,
John L Kelly
Department of Plastic and Reconstructive Surgery, Galway University Hospital, Galway, Ireland
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Background The depth of graft harvest and the residual dermis available for reepithelization primarily influence the healing of split-skin graft donor sites. When the thigh region is chosen, the authors hypothesize based on thickness measurements that the anterolateral region is the optimal donor site.

Methods Full-thickness skin specimens were sampled from the anteromedial, anterior, and anterolateral regions of human cadavers. Skin specimens were cut perpendicularly with a custom-made precision apparatus to avoid the overestimation of thickness measurements. The combined epidermal and dermal thicknesses (overall skin thickness) were measured using a digital calliper. The specimens were histologically stained to visualize their basement membrane, and microscopy images were captured. Since the epidermal thickness varies across the specimen, a stereological method was used to eliminate observer bias.

Results Epidermal thickness represented 2.5% to 9.9% of the overall skin thickness. There was a significant difference in epidermal thickness from one region to another (P<0.05). The anterolateral thigh region had the most consistent and highest mean epidermal thickness (60±3.2 µm). We observed that overall skin thickness increased laterally from the anteromedial region to the anterior and anterolateral regions of the thigh. The overall skin thickness measured 1,032±435 µm in the anteromedial region compared to 1,220±257 µm in the anterolateral region.

Conclusions Based on skin thickness measurements, the anterolateral thigh had the thickest epidermal and dermal layers. We suggest that the anterolateral thigh region is the optimal donor site for split-skin graft harvests from the thigh.

Keywords

Skin surgery - Skin - Photomicrography - Cadaver - Histology

The authors acknowledge Mr. John Fury, Senior Anatomy Technician from the Department of Anatomy, National University of Ireland, Galway for his kind support and assistance throughout this study. The authors also acknowledge the donors to the School of Medicine (Department of Anatomy), National University of Ireland, Galway for making this study possible.




Publication History

Received: 20 July 2014

Accepted: 23 September 2014

Article published online:
05 May 2022

© 2014. The Korean Society of Plastic and Reconstructive Surgeons. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonCommercial License, permitting unrestricted noncommercial use, distribution, and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes. (https://creativecommons.org/licenses/by-nc/4.0/)

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