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Arquivos Internacionais de Otorrinolaringologia 2010; 14(02): 243-246
DOI: 10.7162/S1809-48722010000200016
Case Report
Thieme Publicações Ltda Rio de Janeiro, Brazil

Isolated Laryngeal Amyloidosis Nodular: A Case Report

Amiloidose Laríngea Nodular Isolada: Relato de Caso
Ricardo Rodrigues Figueiredo
*   Master in General Surgery-Otorhinolaryngology, Federal University of Rio de Janeiro. Associate Professor and Head of the Department of Otolaryngology, Faculty of Medicine of Valencia.
,
Andréia Aparecida de Azevedo
**   Otorhinolaryngologist. OTOSUL of ENT, ENT South Fluminense.
› Author Affiliations
Further Information

Publication History

13 April 2009

04 July 2009

Publication Date:
13 February 2014 (online)

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Summary

Introduction: Isolated amyloidosis of the larynx is rare, being the single most common location in head and neck. Can be divided into diffuse and nodular, and the surgical treatment priority.

Objective: To describe a case of isolated nodular amyloidosis of the larynx, with review of literature.

Case report: A female patient, 23 years, presented with complaints of dysphonia and cervical cake for about three months. A laryngoscopy revealed a polypoid lesion of large volume in the left vocal cord. Underwent microsurgery for the removal of the larynx, the histopathological report was consistent with amyloidosis, and underwent further simplified for clinical research locations extralaryngeal of amyloidosis, which was negative. It remains in clinical and laryngoscopic semester.

Final Comments: The isolated amyloidosis of the larynx, although rare, should always be entertained by the otolaryngologist, since it is the most frequent clinical presentation of disease in head and neck, often indistinguishable in appearance to that of other benign lesions. It is indispensable for research extralaryngeal demonstrations.

Resumo

Introdução: A amiloidose isolada da laringe é rara, sendo a localização isolada mais comum em cabeça e pescoço. Pode ser dividida em difusa e nodular, sendo o tratamento prioritariamente cirúrgico.

Objetivo: Descrever um caso de amiloidose nodular isolada de laringe, com revisão da literatura.

Relato do Caso: Paciente do sexo feminino, 23 anos, apresentou-se com queixas de bolo cervical e disfonia há cerca de 3 meses. A videolaringoscopia revelou lesão de aspecto polipoide de grande volume em prega vocal esquerda. Submetida à remoção por microcirurgia de laringe, o laudo histopatológico foi compatível com amiloidose, sendo submetida à investigação clínica adicional simplificada para localizações extralaríngeas de amiloidose, a qual foi negativa. Permanece em acompanhamento clínico e laringoscópico semestral.

Comentários Finais: A amiloidose isolada da laringe, apesar de rara, deve ser sempre cogitada pelo otorrinolaringologista, uma vez que se trata da apresentação clínica mais frequente da doença em cabeça e pescoço, com aspecto muitas vezes indistinguível ao de outras lesões benignas. É indispensável a investigação para manifestações extralaríngeas.

Keywords

amyloidosis - larynx - laryngeal diseases

Palavras-chave

amiloidose - laringe - doenças da laringe
 

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