RSS-Feed abonnieren
![](/products/assets/desktop/img/oa-logo.png)
DOI: 10.7162/S1809-48722010000200016
Isolated Laryngeal Amyloidosis Nodular: A Case Report
Amiloidose Laríngea Nodular Isolada: Relato de CasoPublikationsverlauf
13. April 2009
04. Juli 2009
Publikationsdatum:
13. Februar 2014 (online)
![](https://www.thieme-connect.de/media/10.1055-s-00026220/201002/lookinside/thumbnails/10-7162-s-1809-48722010000200016_140216-1.jpg)
Summary
Introduction: Isolated amyloidosis of the larynx is rare, being the single most common location in head and neck. Can be divided into diffuse and nodular, and the surgical treatment priority.
Objective: To describe a case of isolated nodular amyloidosis of the larynx, with review of literature.
Case report: A female patient, 23 years, presented with complaints of dysphonia and cervical cake for about three months. A laryngoscopy revealed a polypoid lesion of large volume in the left vocal cord. Underwent microsurgery for the removal of the larynx, the histopathological report was consistent with amyloidosis, and underwent further simplified for clinical research locations extralaryngeal of amyloidosis, which was negative. It remains in clinical and laryngoscopic semester.
Final Comments: The isolated amyloidosis of the larynx, although rare, should always be entertained by the otolaryngologist, since it is the most frequent clinical presentation of disease in head and neck, often indistinguishable in appearance to that of other benign lesions. It is indispensable for research extralaryngeal demonstrations.
Resumo
Introdução: A amiloidose isolada da laringe é rara, sendo a localização isolada mais comum em cabeça e pescoço. Pode ser dividida em difusa e nodular, sendo o tratamento prioritariamente cirúrgico.
Objetivo: Descrever um caso de amiloidose nodular isolada de laringe, com revisão da literatura.
Relato do Caso: Paciente do sexo feminino, 23 anos, apresentou-se com queixas de bolo cervical e disfonia há cerca de 3 meses. A videolaringoscopia revelou lesão de aspecto polipoide de grande volume em prega vocal esquerda. Submetida à remoção por microcirurgia de laringe, o laudo histopatológico foi compatível com amiloidose, sendo submetida à investigação clínica adicional simplificada para localizações extralaríngeas de amiloidose, a qual foi negativa. Permanece em acompanhamento clínico e laringoscópico semestral.
Comentários Finais: A amiloidose isolada da laringe, apesar de rara, deve ser sempre cogitada pelo otorrinolaringologista, uma vez que se trata da apresentação clínica mais frequente da doença em cabeça e pescoço, com aspecto muitas vezes indistinguível ao de outras lesões benignas. É indispensável a investigação para manifestações extralaríngeas.
-
Bibliographical References
- 1 Pribtikin E, Friedman O, OHara B, Cunnane MF, Levi D, Rosen M, Keane WM, Sataloff RT. Amyloidosis of the upper aerodigestive tract. Laryngoscope 2003; 113: 2095-2101
- 2 Penner CR, Müller S. Head an neck amyloidosis: a clinicopathologic study of 15 cases. Oral Oncol 2006; 42: 421-429
- 3 Motta G, Salzano FA, Motta S, Staibano S. CO2-laser treatment of laryngeal amyloidosis. J Laryngol Otol 2003; 117: 647-650
- 4 Valera FCP, Fomin DS, Maggioni Jr GS, Grellet M. Amiloidose localizada laríngea: relato de caso e revisão de literatura. Rev Bras Otorrinolaringol 2004; 70 (3) 423-426
- 5 Akst L, Thompson LDL. Larynx amyloidosis. Ear Nose Throat J 2003; 82 (11) 844-845
- 6 Benning S, Technau-Ihling K, Fisch P, Fradis M, Schipper J, Maier W. Amyloid tumor of the larynx associated with plasma cell infiltration: Differential diagnosis. Ear Nose Throat J 2004; 83 (12) 839-843
- 7 Borrow A, Neumann L. Amiloide degeneration von larynx tumoren, canule sieben jahre lang getragen. Arch Kilin Chir 1875; 18: 242-246
- 8 Alaani A, Warfield AT, Path FRC, Pracy JP. Management of laryngeal amyloidosis. J Laryngol Otol 2004; 118: 279-283
- 9 Çankaya H, Egeli E, Ünal Ö, Kiris M. Laryngeal amyloidosis: a rare cause of laryngocele. J Clin Imag 2002; 26: 86-88
- 10 Barnes EL, Zafer T. Laryngeal amyloidosis: clinocpathology study of seven cases. Ann Otol Rhinol Laryngol 1977; 86: 856-863
- 11 Mitrani M, Biller HF. Laryngeal amyloidosis. Laryngoscope 1985; 95: 1346-1347
- 12 Desuter G, Hamoir H, Van Geem C, Boucquey D. Laryngeal amyloidosis: a case of adidas-stripes larynx. Ear Nose Throat J 2007; 85: 378
- 13 Sataloff R, Abaza M, Abaza NA, Markiewicz A, Hawkshaw M. Amyloidosis of the larynx. Ear Nose Throat J 2001; 80: 389-390
- 14 Aydin O, Ustundag E, Iseri M, Ozkarakas H, Oguz A. Laryngeal amyloidosis with laryngocele. J Laryngol Otol 1999; 113: 361-363
- 15 Gean-Marton AD, Kirsch CF, Vezina IG, Weber AL. Focal amyloidosis of the head and neck: evaluation with the CT and MR imaging. Radiology 1991; 181 (2) 521-5