Prenatal Diagnosis of Fetus in Fetu pregnancy

Malena Goette; Guido Seitz; Reza Vahdad; Florian Obermayr; Kerstin Gummel; Andreas Mahnken; Christian Enzensberger; Roland Axt-Fliedner

doi:10.1055/a-0605-5078

Zeitschrift für Geburtshilfe und Neonatologie, Table of Contents

Z Geburtshilfe Neonatol 2018; 222(03): 123-127
DOI: 10.1055/a-0605-5078

Case Report

Prenatal Diagnosis of Fetus in Fetu pregnancy

Pränatale Diagnose eines Fetus in Fetu

Malena Goette

¹Department of OB/GYN, Division of Prenatal Medicine, University Hospital UKGM, Justus-Liebig University, Giessen, Germany

,

Guido Seitz

²Department of Pediatric Surgery, University Hospital UKGM, Philipps University of Marburg, Marburg, Germany

,

Reza Vahdad

²Department of Pediatric Surgery, University Hospital UKGM, Philipps University of Marburg, Marburg, Germany

,

Florian Obermayr

²Department of Pediatric Surgery, University Hospital UKGM, Philipps University of Marburg, Marburg, Germany

,

Kerstin Gummel

³Center of Obstetrics and Gynecology, University Hospital UKGM, Philipps University of Marburg, Marburg, Germany

,

Andreas Mahnken

⁴Department of Diagnostic and Interventional Radiology, University Hospital UKGM, Philipps University of Marburg, Marburg, Germany

,

Christian Enzensberger

¹Department of OB/GYN, Division of Prenatal Medicine, University Hospital UKGM, Justus-Liebig University, Giessen, Germany

,

Roland Axt-Fliedner

⁵Division of Prenatal Medicine, Department of Obstretrics and Gynecology, Giessen, Justus-Liebig-University, Germany

› Author Affiliations

Abstract

Fetus in fetus (FIF) represents an abnormal embryogenesis in monozygotic diamniotic twin gestation. It has been described in less than 200 cases worldwide. Differential diagnosis predominantly includes teratomas. The case presented here meets the accepted criteria of FIF and is one of the few prenatally diagnosed cases with FIF.

Zusammenfassung

In diesem Fallbericht werden die Kriterien einer Fetus-in-Fetu-Malformation erfüllt. Es ist einer der wenigen pränatal diagnostizieren Fälle und der einzige pränatale Fall mit extrafetalem Wachstum des parasitären Zwilling. Die wichtigste Differentialdiagnose eines Fetus in Fetu ist das Teratom. Die Therapie der Wahl ist die kompette Resektion, jedoch von dem Allgemeinzustand und zusätzlichen Fehlbildungen abhängig. Mit detaillierter Sonografie und moderner Bildgebung kann eine pränatale Diagnose gestellt werden und ermöglicht dadurch einen frühen und intedisziplinären Therapieansatz.

Key words

ultrasound - twin pregnancy - therapy - prenatal diagnostics - malformations - neonatology

Schlüsselwörter

Fehlbildung - Zwillingsschwangerschaft - Ultraschall - Therapie - Neonatologie - Pränataldiagnostik

Full Text

References

References
1 Mustafa G, Mirza B, Iqbal S. et al. A case of fetus in fetu. APSP J Case Rep 2012; 3: 9
2 Gangopadhyay A, Srivastava A, Srivastava P. et al. Twin fetus in fetu in a child: a case report and review of the literature. J Med Case Reports 2010; 4: 96
3 Kurdi A, Al-Sasi O, Asiri S. et al. Fetus-in-fetu. Imaging and pathology. Saudi Med J 2012; 33: 444-448
4 Sharma A, Goyal A, Sharma S. et al. Fetus in fetu: A rare case report. J Res Med Sci 2012; 17: 491-494
5 Majhi A, Saha K, Karmakar M. et al. Fetus in fetu – a mystery in medicine. Sci World J 2007; 7: 252-257
6 Gonzalez-Crussi F. Extragonadal Teratomas (Atlas of Tumor Pathology). Washington, DC: Armed Forces Institute of Pathology; 1982
7 Spencer R. Parasitic conjoined twins: External, internal (fetuses in fetu and teratomas), and detached (acardiacs). Clin Anat 2001; 14: 428-444
8 Hoeffel C, Nguyen K, Phan H. et al. Fetus in fetu: A case report and literature review. Pediatrics 2001; 105: 1335-1344
9 Ji Y, Song B, Chen S. et al. Fetus in fetu in the scrotal sac: Case report and literature review. Medicine 2015; 94: e1322
10 Sitharama S, Jindal B, Vuriti M. et al. Fetus in fetu: Case report and brief review of literature on embryologic origin, clinical presentation, imaging and differential diagnosis. Pol J Radiol 2017; 82: 46-49
11 Tiwari Charu Shah et al Fetus in fetu: Two cases and literature review. Dev Period Med 2016; 20: 174-177
12 Tran M, Landin M, Blackwood B. et al. Fetus in fetu – a case report with a variant host anastomosis. Am Surg 2016; 82: 759-762
13 Ullal Sonali Sanyal et al. A rare case of fetus within a fetus. J Clin Diagn Res 2016; 10: TD03-TD04
14 Padwal A, Dattatraya D, Bhagvatula I. et al. Occipitocervical fetus in fetu with extracalvarial extension: A case report. Pediatr Neurosurg 2016; 51: 87-92
15 Goldberg H, Allen L. Sari et al. Fetiform teratoma in the ovary of a 7-year-old girl: A case report. J Pediatr Adolesc Gynecol 2017; 30: 256-258
16 Enaud R, Lavrand F, Le M. et al. Intraperitoneal fetus in fetu: A rare cause of abdominal mass. J Pediatr Gastroenterol Nutr 2017; 65: e69
17 Krekora M, Zych-Krekora K, Blitek M. et al. Difficulties in prenatal diagnosis of tumour in the fetal sacrococcygeal area. Ultrasound (Leeds, England) 2016; 24: 119-124
18 Götte M, Seitz G, Vahdad R et al. Prenatal diagnosis of fetus in fetu pregnancy. Zeitschrift für Geburtshilfe und Neonatologie 2018
19 Newcomb L, Rhee E, Bean S. et al. Pregnancy complicated by foetal abdominal mass: Fetiform teratoma versus foetus-in-fetu. J Obstet Gynaecol 2017; 37: 815-817
20 Song Q, Jiang X, Jiang Y. et al. Fetus in fetu: From prenatal sonographic diagnosis to postnatal confirmation. Fetal Diagn Ther 2016; 39: 158-160
21 Mills P, Bornick P, Morales W. et al. Ultrasound prenatal diagnosis of fetus in fetu. Ultrasound Obstet Gynecol 2001; 18: 69-71
22 Hui P, Wah L, Tina P. et al. Fetus in fetu – from prenatal ultrasound and MRI diagnosis to postnatal confirmation. Prenat Diagn 2007; 27: 657-661
23 House M, Pahuja M, Bethune M. et al. Pre- and postnatal diagnosis of fetus-in-fetu. Australas Radiol 2005; 49: 512-515
24 Has R, Kalelioglu I, Esmer AC. et al. Prenatal sonographic diagnosis of fetus in fetu. J Ultrasound Med 2013; 32: 2212-2214
25 Ianniruberto A, Rossi P, Ianniruberto M. et al. Sonographic prenatal diagnosis of intracranial fetus in fetu. Ultrasound Obstet Gynecol 2001; 18: 67-68