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DOI: 10.1055/a-0632-3930
Periradicular Infiltration of the Cervical Spine: How New CT Scanner Techniques and Protocol Modifications Contribute to the Achievement of Low-Dose Interventions
Periradikuläre Infiltrationstherapie der Halswirbelsäule: Wie die Technik neuer CT Scanner und Modifikationen des Untersuchungsprotokolls zur Durchführung von low-dose-Interventionen beitragenCorrespondence
Publikationsverlauf
04. Oktober 2017
16. Mai 2018
Publikationsdatum:
18. Juni 2018 (online)
Abstract
Purpose CT-guided periradicular infiltration of the cervical spine is an effective symptomatic treatment in patients with radiculopathy-associated pain syndromes. This study evaluates the robustness and safety of a low-dose protocol on a CT scanner with iterative reconstruction software.
Materials and Methods A total of 183 patients who underwent periradicular infiltration therapy of the cervical spine were included in this study. 82 interventions were performed on a new CT scanner with a new intervention protocol using an iterative reconstruction algorithm. Spot scanning was implemented for planning and a basic low-dose setup of 80 kVp and 5 mAs was established during intermittent fluoroscopy. The comparison group included 101 prior interventions on a scanner without iterative reconstruction. The dose-length product (DLP), number of acquisitions, pain reduction on a numeric analog scale, and protocol changes to achieve a safe intervention were recorded.
Results The median DLP for the whole intervention was 24.3 mGy*cm in the comparison group and 1.8 mGy*cm in the study group. The median pain reduction was –3 in the study group and –2 in the comparison group. A 5 mAs increase in the tube current-time product was required in 5 patients of the study group.
Conclusion Implementation of a new scanner and intervention protocol resulted in a 92.6 % dose reduction without a compromise in safety and pain relief. The dose needed here is more than 75 % lower than doses used for similar interventions in published studies. An increase of the tube current-time product was needed in only 6 % of interventions.
Key Points:
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The presented ultra-low-dose protocol allows for a significant dose reduction without compromising outcome.
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The protocol includes spot scanning for planning purposes and a basic setup of 80 kVp and 5 mAs.
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The iterative reconstruction algorithm is activated during fluoroscopy.
Citation Format
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Elsholtz FH, Kamp JE, Vahldiek JL et al. Periradicular Infiltration of the Cervical Spine: How New CT Scanner Techniques and Protocol Modifications Contribute to the Achievement of Low-Dose Interventions. Fortschr Röntgenstr 2019; 191: 54 – 61
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Zusammenfassung
Ziel Die CT-gestützte periradikuläre Infiltrationstherapie der Halswirbelsäule stellt eine effektive symptomatische Behandlungsmethode bei Patienten mit Radikulopathie-bedingtem Schmerzsyndrom dar. Diese Studie evaluiert die Robustheit und Sicherheit eines low-dose-Protokolls bei einem CT Scanner mit iterativer Rekonstruktionssoftware.
Material und Methoden 183 Patienten nach periradikulärer Infiltrationstherapie der Halswirbelsäule wurden in diese Studie eingeschlossen. 82 Interventionen wurden auf einem neuem CT Scanner mit neuem Protokoll und Einsatz eines iterativen Rekonstruktionsalgorithmus durchgeführt. Spot Scanning wurde zur Planung eingesetzt und während der Fluoroskopie ein Basis-Setup von 80 kVp und 5 mAs verwendet. Die Vergleichsgruppe umfasste 101 zuvor durchgeführte Interventionen mit einem CT Scanner ohne iterative Rekonstruktionssoftware. Das Dosis-Längen-Produkt, die Anzahl der Akquisitionen, die Schmerzreduktion anhand einer numerischen Analogskala und eventuelle Protokolländerungen zur sicheren Durchführung der Intervention wurden registriert.
Ergebnisse Das mediane DLP für die gesamte Intervention betrug 24,3 mGy*cm in der Vergleichsgruppe und 1,8 mGy*cm in der Studiengruppe. Die mediane Schmerzreduktion betrug –3 in der Studiengruppe und –2 in der Vergleichsgruppe. Eine Erhöhung des Röhrenstrom-Zeit-Produktes um 5 mAs war bei 5 Patienten der Studiengruppe erforderlich.
Schlussfolgerung Die Einführung eines neuen CT Scanners mit einem neuen Interventionsprotokoll führte zur einer Dosisreduktion um 92,6 % ohne Einbußen in Sicherheit und Schmerzreduktion. Die benötigte Dosis liegt mehr als 75 % unter den benötigten Dosen vergleichbarer Interventionen, die in bisherigen Studien veröffentlicht wurden. Eine Erhöhung des Röhrenstrom-Zeit-Produktes war in nur 6 % der Interventionen notwendig.
Kernaussagen:
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Das vorgestellte Ultra-low-dose-Protokoll ermöglicht eine signifikante Dosisreduktion ohne Minderung des Therapieerfolges.
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Das Protokoll beinhaltet Spot Scanning zur Interventionsplanung und ein Basis Setup von 80 kVp und 5 mAs.
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Während der Fluoroskopie ist ein iterativer Rekonstruktionsalgorithmus aktiviert.
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Key words
interventional radiology - computed tomography - spine - cervical - injection - radiation dosageIntroduction
Periradicular infiltration therapy is an effective symptomatic treatment performed in patients with radiculopathy-associated pain syndromes [1]. Periradicular infiltration therapy has shown to be especially effective in patients with underlying disc prolapse, which is among the most frequent causes of cervical radiculopathy [2] [3]. It is an interventional procedure that is offered to patients in whom conservative measures such as drug treatment have been exhausted [4]. Recent studies suggest that the outcome is best when both strategies are combined [5]. Unlike epidural space infiltration (ESI), periradicular infiltration is a targeted procedure with side-specific nerve root infiltration [6].
The intervention can be performed with or without imaging guidance. While conventional fluoroscopy is still the standard modality, the sectional imaging modalities CT and MRI are also well evaluated. CT is receiving more and more acceptance in the interventional routine and it has also been implemented to guide pain management [8]. Its wide use has also raised concerns in terms of radiation exposure for patients and interventionalists [9] [10] [11] [12] and much research effort has been spent on dose reduction in diagnostic and also interventional CT [13] [14] [15].
Approaches to lowering the radiation dose of CT involve modifications of acquisition parameters such as tube current-time product, tube voltage and acquisition coverage [16]. More recently, the use of state-of-the-art image reconstruction software beyond standard filtered back projection (FBP) facilitates the restoring of image quality in low-dose scans [17] [18]. The effective combination of all these options while monitoring clinical outcome is the main focus of this study.
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Materials and Methods
Patients
The Institutional Review Board (IRB) approved this retrospective study, which included 183 patients – 82 patients in the study group and 101 patients in the comparison group. All patients underwent single-site periradicular infiltration therapy of the cervical spine for pain relief. The inclusion criteria were age over 18 years, focal neurological symptoms caused by cervical nerve root compression, and no prior surgical or interventional therapy. Informed consent was obtained.
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Patient groups and CT protocols
Periradicular infiltration in the study group was accomplished with image guidance on an 80-slice CT scanner (Toshiba Aquilion PRIME, Toshiba Medical Systems, Ottawara, Japan) equipped with the adaptive iterative dose reduction (AIDR 3 D) iterative reconstruction software (Toshiba Medical Systems, Ottawara, Japan). Patients were positioned supine. Acquisition of a lateral scanogram was followed by small volume spot scanning of the segment to be treated ([Fig. 1]). Spot scanning means a single volume acquisition with reconstruction of 4 images each with a 1-mm slice thickness (100 kVp and 10 mAs, 0.5 s rotation time). The step-and-shoot technique (intermittent fluoroscopy at 80 kVp and 5 mAs, 0.5 s rotation time, slice thickness 4 mm) allowed correct advancement of the needle ([Fig. 2]) [19]. If image quality was insufficient (poor delineation of needle and/or neuroforamen), the tube current-time product was raised in increments of 5 mAs (“bottom-up strategy”).
![](https://www.thieme-connect.de/media/roefo/201901/thumbnails/roefo-2929_10-1055-a-0632-3930-i1.jpg)
![Zoom Image](/products/assets/desktop/css/img/icon-figure-zoom.png)
Abb. 1 a–e 45 Jahre alte weibliche Patientin mit periradikulärer Infiltrationstherapie auf der rechten Seite im Segment HWK 2/3. Die Planung umfasst ein laterales Scanogramm a gefolgt von Spot Scanning durch Akquisition von 4 axialen Bildern in 1 mm Schichtdicke d, e des zu behandelnden Wirbelsäulensegmentes. Die Dosis des Spot Scanning beträgt hier 0,80 mGy*cm.
![](https://www.thieme-connect.de/media/roefo/201901/thumbnails/roefo-2929_10-1055-a-0632-3930-i2.jpg)
![Zoom Image](/products/assets/desktop/css/img/icon-figure-zoom.png)
Abb. 2 a–d Dieselbe Patientin wie in Abb. 1. Periradikuläre Infiltrationstherapie auf der rechten Seite im Segment HWK 2/3. Die Bilder in axialer Schichtführung a–d wurden mit 4 mm Schichtdicke unter Anwendung der step-and-shoot-Technik akquiriert. Bild d zeigt die Testinjektion mit verdünntem Kontrastmittel.
The protocol used in the comparison group differed from the protocol in the study group as follows: CT guidance was performed on a 64-slice scanner (Siemens SOMATOM Definition, first Generation Dual Source Scanner, 2005, Siemens Healthcare, Erlangen, Germany) using standard image reconstruction with FBP. Small-volume spot scanning was not available on this scanner. For planning purposes, a scanogram was followed by a focal helical planning CT (100 kVp, automatic tube current modulation, 0.75-mm slice thickness). The length of this acquisition was defined by the interventionalist. The interventional part differed from the study group only in terms of acquisition parameters (100 kVp, 28 mAs, 5 mm slice thickness).
There was no access to previous diagnostic imaging data in either group. Access was accomplished via the transforaminal route in all cases. Correct needle placement was confirmed with an injection of contrast medium (0.5 ml Hexabrix 320, Guerbet, Roissy, France) diluted with a local anesthetic (2 ml bupivacaine, Carbostesin 0.5 %, AstraZeneca GmbH, Wedel, Germany). Finally, the interventionalist administered the therapeutic injection of glucocorticoid (1 ml dexamethasone, Lipotalon, Merckle Recordati GmbH, Ulm, Germany).
The tube current-time product (mAs), tube voltage (kVp), the resulting cumulative dose-length product (DLP) in mGy*cm, and the number of interventional acquisitions were documented for each intervention. For evaluation of the outcome, patients were asked to assess their average pain on a standardized numeric rating scale from 0 (“no pain”) to 10 (“worst pain one can imagine”) immediately before the intervention and again 6 weeks after.
To rule out experience bias in the two groups, radiologists with different work experience performed the interventions. In the study group, 54 interventions were performed by an experienced radiologist (A: 13 years of work experience) and 28 interventions by a resident radiologist (B: 3 years of work experience). In the comparison group the same radiologist A performed 69 interventions and another radiologist C (also 3 years of work experience) performed 32 interventions.
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Data analysis
Statistics
Statistical analysis was performed using base R (version 3.2.3, R Foundation for Statistical Computing, Vienna, Austria). Plots were generated using the lattice package.
First, the Shapiro-Wilk test was applied to test for normal distribution. As it indicated non-normal distribution, the nonparametric Wilcoxon rank-sum test was used to test for differences in variables between the two groups. The chi-squared test was used to test for differences in variables between the groups only with respect to sex. Statistical significance was assumed for p-values < 0.05.
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Dose
The dose-length product (DLP) is the most common parameter for comparing radiation doses of CT examinations. It is calculated as the Computed Tomography Dose Index (CTDIvol) multiplied by the scan length:
DLP = CTDI * scan length [unit: mGy*cm]
DLP and CTDIvol are X-ray tube output metrics [20]. To estimate the dose absorbed by the patient in terms of population-based stochastic health risk, effective dose was introduced [21]. It is calculated by multiplying DLP with a tissue-specific conversion factor. In this study the current conversion factor for cervical spine imaging of 0.0057 [22] was applied:
![](https://www.thieme-connect.de/media/roefo/201901/thumbnails/roefo-2929_10-1055-a-0632-3930-i5.jpg)
![Zoom Image](/products/assets/desktop/css/img/icon-figure-zoom.png)
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Results
Patient demographics are compiled in [Table 1] and data on the treated spinal segments and body sides are presented in [Table 2].
BMI: body mass index.
BMI: Body Mass Index.
The total median DLP was significantly decreased from 24.30 mGy*cm (effective dose: 0.13 mSv) in the comparison group to 1.80 mGy*cm (0.01 mSv) in the study group, corresponding to a 92.6 % reduction. The planning part accounted for 91 % of the total DLP in the comparison group versus 44 % in the study group. A significant dose reduction from 1.70 mGy*cm (0.01 mSv) to 0.95 mGy*cm (0.005 mSv, p = 0.01) was also accomplished for the interventional part. The median self-reported pain reduction was –3 in the study group and –2 in the comparison group; the difference was not significant (p = 0.80).
Differences in the level of experience between the radiologists performing the interventions had no effect on the DLP in the study group, which was a median of 1.80 mGy*cm for radiologists A and B.
In the comparison group, the median DLP was 24.20 mGy*cm for radiologist A and 28.90 mGy*cm for radiologist B. The difference in overall dose was not significant in the study group (p = 0.48) or in the comparison group (p = 0.07).
A higher tube current-time product was necessary in 5 patients of the study group to achieve adequate demarcation of the neuroforamen. All of them were treated in the C 6/7 segment ([Fig. 3]).
![](https://www.thieme-connect.de/media/roefo/201901/thumbnails/roefo-2929_10-1055-a-0632-3930-i3.jpg)
![Zoom Image](/products/assets/desktop/css/img/icon-figure-zoom.png)
Abb. 3 a, b 49 Jahre alte weibliche Patientin mit periradikulärer Infiltrationstherapie im Segment HWK 6/7 auf der rechten Seite. Axiale Bilder wurden mit 4 mm Schichtdicke akquiriert. Das Basis Setup von 80 kVp und 5 mAs a wurde als unzureichend eingeschätzt um die Zielstrukturen Neuroforamen und Position der Arteria vertebralis deutlich abzugrenzen. Dies hätte eine sichere Positionierung der Nadel beeinträchtigen können. Eine Erhöhung auf 10 mAs b verbesserte die Bildqualität und erlaubte eine adäquate finale Positionierung.
[Table 3] compiles the results for all parameters measured in the two groups. In [Fig. 4], dose distributions for each step and group are juxtaposed. To represent these data in a single diagram, the y-axis had to be scaled as decadic logarithm of the DLP.
study group |
comparison group |
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median |
range |
median |
range |
p-value |
|
(Q1–Q3) |
(Q11–Q3) |
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DLP planning (mGy*cm) |
0.80 |
0.80 – 0.80 (0.80 – 0.80) |
22.00 |
4.00 – 27.00 (16.00 – 27.00) |
< 0.01[1] |
DLP intervention (mGy*cm) |
0.95 |
0.50 – 4.10 (0.80 – 1.20) |
1.70 |
0.60 – 8.60 (1.20 – 2.60) |
< 0.011 |
acquisitions |
9.00 |
2.00 – 25.00 (8.00 – 12.00) |
7.00 |
4.00 – 33.00 (8.00 – 15.00) |
0.031 |
DLP total (mGy*cm) |
1.80 |
1.30 – 4.90 (1.60 – 2.00) |
24.30 |
7.60 – 312.90 (18.50 – 29.20) |
< 0.011 |
calculated total effective dose (mSv) |
0.01 |
0.01 – 0.03 (0.01 – 0.01) |
0.139 |
0.04 – 1.79 (0.11 – 0.17) |
< 0.011 |
pain before (NRS) |
7.00 |
1.00 – 10.00 (6.00 – 8.00) |
7.00 |
3.00 – 10.00 (7.00 – 8.00) |
0.10 |
pain after (NRS) |
4.00 |
0.00 – 9.00 (3.00 – 6.00) |
5.00 |
1.00 – 9.00 (4.00 – 6.00) |
0.06 |
pain relief (NRS) |
–3.00 |
–1.00 – –6.00 (–1.00 – –4.00) |
–2.00 |
–1.00 – –6.00 (–1.00 – –3.00) |
0.80 |
Q1–Q3: interquartile range. DLP: dose-length product, NRS: numeric rating scale.
Q1–Q3: Interquartilsabstand. DLP: Dosis-Längen-Produkt, NRS: Numerische Rating-Skala.
1 significant difference.
signifikanter Unterschied.
![](https://www.thieme-connect.de/media/roefo/201901/thumbnails/roefo-2929_10-1055-a-0632-3930-i4.jpg)
![Zoom Image](/products/assets/desktop/css/img/icon-figure-zoom.png)
Abb. 4 In der Vergleichsgruppe entfällt der größte Anteil der Gesamtdosis auf das Planungs-Spiral-CT. Eine signifikante Reduktion der Gesamtdosis kann durch Spot Scanning zu Planungszwecken erreicht werden. Die Boxplots mit logarithmischer Skala zeigen das mediane DLP für jeden Schritt der periradikulären Infiltrationstherapie in der Studiengruppe und der Vergleichsgruppe. Die Balken geben den Median, die Boxen die 25te und 75te Perzentile an. Die leeren Kreise repräsentieren Ausreißer außerhalb der Whisker.
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Discussion
Dose reduction in interventional CT remains a hot topic as the overall dose mirrors the cumulative ionizing radiation repeatedly applied to a focal region. Despite all efforts to reduce dose, safety must never be compromised. In our study we achieved an overall dose reduction for complete periradicular infiltration therapy that has not been accomplished before, both in our institutional comparison group and in previous studies reported in the literature. Moreover, this dose reduction has been accomplished without lowering patient safety during the intervention. Even if our study design provided a comparison group, the main aspect is the very low median dose level achieved in the study group. The scanner setup during intermittent fluoroscopy could even be optimized in terms of dose reduction with respect to recently published low-dose protocols for the lumbar spine on the same scanner [14] [15]. This mainly refers to the smaller cervical body diameter where 80 kV (towards 100 kV) is sufficient during intermittent fluoroscopy. In another comparable study Paik reported a median DLP of 7.92 mGy*cm for his own new protocol for cervical TFESI (Transforaminal Epidural Space Injection), which is similar to the periradicular infiltration therapy we performed in our study [23]. The median DLP of 1.80 mGy*cm in our study group, which corresponds to just 22.72 % of the dose reported by Paik. Kranz et al. published data on the safety and technique, including tube parameters, of cervical interlaminar ESI without mentioning overall dose [13]. They used a range of tube currents from 30 to 150 mA, making it likely that overall doses were higher than accomplished in our study. In our study, we modified multiple parameters to achieve a dose reduction. First, acquisition of a volume for planning purposes (spot scanning) instead of a helical scan made a substantial contribution to dose reduction in our approach. Second, reducing the tube current-time product to its lowest possible level (5 mAs) was possible on the condition that the acquired images are not of diagnostic image quality but ensure safe completion of the intervention. If the safety criteria as explained above were not met, the dose had to be increased. Iterative reconstruction software is available on an increasing number of state-of-the-art CT scanners. We assume that the dose reduction achieved with the use of AIDR 3 D in diagnostic imaging can also be exploited to reduce the dose in the interventional setting. Self-reported pain assessment by our patients strongly suggests that dose reduction did not impair the outcome of the intervention. Utilizing the numeric rating scale helped to objectify the success of the intervention and revealed no statistically significant difference between the study group and comparison group, even though we measured a reduction from –3 to –2. Our interventional approach also fits into the current trend toward increased use of transforaminal access routes in periradicular infiltration therapy or ESI [24]. Therefore, the protocol presented here should be of interest to most interventional radiologists.
All 5 patients in whom the radiologists decided to raise the tube current time-product to 10 mAs were treated in the C 6/7 segment. Here, the poorer image quality is mainly attributable to the fact that the shoulder is in the acquisition field, so it might already have been apparent from the referral note that a higher tube current-time product would be needed in these patients. The number of acquisitions needed to complete the intervention corresponds linearly to the applied dose.
In our study, there was no difference in overall dose between interventions performed by the more experienced radiologist (A) and those performed by the resident radiologist (B). This finding indicates robustness of the protocol against different levels of work experience. Successful implementation of this protocol for periradicular interventions might contribute to dose reduction efforts in other CT-guided interventions in high-contrast regions such as bone biopsy, thoracocentesis, and lung biopsy. This expectation has been confirmed by initial experience with other interventions in our institution.
Our study has some limitations including the retrospective design. Mainly it compares interventional protocols performed on scanners of different generations and hence different technical features. While features of the modern scanner have nearly been exhausted to reduce dose, there would still have been room for adjustments in the protocol of the comparison group to also achieve significant dose reduction, e. g. a standardized length of the helical planning scan. Other features such as reducing the tube current-time product to 5 mAs are not available on the older scanner. On this view the study design might look unfair but it also reflects the clinical reality we experienced. This study underlines the opportunity for significant protocol adjustments when new scanner generations replace older ones. Furthermore, more accurate dose estimates might have been obtained using a size-specific dose estimate (SSDE), which includes patient diameter for calculating radiation doses. However, as this dose estimate is not automatically available on most CT scanners and for better comparability with published data, we opted for DLP in our study. Our exemplary calculations of SSDE yielded even lower overall doses compared with DLP. Basically, the estimation of radiation-induced risks deriving from low-dose exposure remains unclear and still needs to be investigated. However, especially with patients tending to undergo multiple interventions, low-dose settings should be favored. The present study complies precisely with the ALARA principle (“as low as reasonably achievable”) by which all dose-related considerations should be guided. Another issue is the measurement of pain. Self-reported pain before and 6 weeks after an intervention is a subjective measure of outcome. Functional scores and long-term surveys were not the focus of this study but could give important additional information on outcome. We used AIDR 3 D to significantly reduce image noise [25] [26]. Like other iterative reconstruction algorithms, it is vendor-specific and the results might be different with algorithms from other vendors. Future studies should focus on quantifying the dose reduction contribution of AIDR 3 D in interventional procedures. Further dose reduction might be possible by reducing the number of spot scanning acquisitions to two or three. This is underlined by the case presented in [Fig. 1], which shows that only images b and c would have been necessary to plan the intervention. Quantification of the contribution of the scanogram to the overall dose was not part of this or any previous study but may contribute to further dose reduction.
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Conclusion
This study proposes a protocol for periradicular infiltration of the cervical spine combining spot scanning for planning purposes and a basic scanner setup of 80 kVp, 5 mAs for intermittent fluoroscopy with the use of an iterative image reconstruction algorithm. The median DLP (1.80 mGy*cm) was more than 75 % lower compared with earlier protocols reported in the literature (7.92 mGy*cm). Hence, it addresses the rising concern in terms of radiation exposure for patients and radiologists. In terms of self-reported pain, a considerable pain reduction of –3 on the numeric rating scale could be achieved.
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Detailed protocol optimization leads to a significant dose reduction in not only the diagnostic but also the interventional use of CT.
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This complies with the ALARA principle (“as low as reasonably achievable”).
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Especially in periradicular infiltration therapy, patients tend to undergo multiple interventions and interventionalists are repeatedly exposed to radiation.
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Iterative reconstruction software is also useful in interventional protocols.
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Die Autoren geben an, dass kein Interessenkonflikt besteht.
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- 25 Gervaise A, Osemont B, Lecocq S. et al. CT image quality improvement using Adaptive Iterative Dose Reduction with wide-volume acquisition on 320-detector CT. European radiology 2012; 22: 295-301 . doi:10.1007/s00330-011-2271-7
- 26 Schindera ST, Odedra D, Raza SA. et al. Iterative reconstruction algorithm for CT: can radiation dose be decreased while low-contrast detectability is preserved?. Radiology 2013; 269: 511-518 . doi:10.1148/radiol.13122349
Correspondence
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References
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- 25 Gervaise A, Osemont B, Lecocq S. et al. CT image quality improvement using Adaptive Iterative Dose Reduction with wide-volume acquisition on 320-detector CT. European radiology 2012; 22: 295-301 . doi:10.1007/s00330-011-2271-7
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![](https://www.thieme-connect.de/media/roefo/201901/thumbnails/roefo-2929_10-1055-a-0632-3930-i1.jpg)
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Abb. 1 a–e 45 Jahre alte weibliche Patientin mit periradikulärer Infiltrationstherapie auf der rechten Seite im Segment HWK 2/3. Die Planung umfasst ein laterales Scanogramm a gefolgt von Spot Scanning durch Akquisition von 4 axialen Bildern in 1 mm Schichtdicke d, e des zu behandelnden Wirbelsäulensegmentes. Die Dosis des Spot Scanning beträgt hier 0,80 mGy*cm.
![](https://www.thieme-connect.de/media/roefo/201901/thumbnails/roefo-2929_10-1055-a-0632-3930-i2.jpg)
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Abb. 2 a–d Dieselbe Patientin wie in Abb. 1. Periradikuläre Infiltrationstherapie auf der rechten Seite im Segment HWK 2/3. Die Bilder in axialer Schichtführung a–d wurden mit 4 mm Schichtdicke unter Anwendung der step-and-shoot-Technik akquiriert. Bild d zeigt die Testinjektion mit verdünntem Kontrastmittel.
![](https://www.thieme-connect.de/media/roefo/201901/thumbnails/roefo-2929_10-1055-a-0632-3930-i5.jpg)
![Zoom Image](/products/assets/desktop/css/img/icon-figure-zoom.png)
![](https://www.thieme-connect.de/media/roefo/201901/thumbnails/roefo-2929_10-1055-a-0632-3930-i3.jpg)
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Abb. 3 a, b 49 Jahre alte weibliche Patientin mit periradikulärer Infiltrationstherapie im Segment HWK 6/7 auf der rechten Seite. Axiale Bilder wurden mit 4 mm Schichtdicke akquiriert. Das Basis Setup von 80 kVp und 5 mAs a wurde als unzureichend eingeschätzt um die Zielstrukturen Neuroforamen und Position der Arteria vertebralis deutlich abzugrenzen. Dies hätte eine sichere Positionierung der Nadel beeinträchtigen können. Eine Erhöhung auf 10 mAs b verbesserte die Bildqualität und erlaubte eine adäquate finale Positionierung.
![](https://www.thieme-connect.de/media/roefo/201901/thumbnails/roefo-2929_10-1055-a-0632-3930-i4.jpg)
![Zoom Image](/products/assets/desktop/css/img/icon-figure-zoom.png)
Abb. 4 In der Vergleichsgruppe entfällt der größte Anteil der Gesamtdosis auf das Planungs-Spiral-CT. Eine signifikante Reduktion der Gesamtdosis kann durch Spot Scanning zu Planungszwecken erreicht werden. Die Boxplots mit logarithmischer Skala zeigen das mediane DLP für jeden Schritt der periradikulären Infiltrationstherapie in der Studiengruppe und der Vergleichsgruppe. Die Balken geben den Median, die Boxen die 25te und 75te Perzentile an. Die leeren Kreise repräsentieren Ausreißer außerhalb der Whisker.