Exercise is medicine: Die Rolle von Zytokinen und Myokinen für Gesundheit und Krankheit

Zusammenfassung

Die Skelettmuskulatur ist das größte Organ normalgewichtiger Personen. Mittlerweile wird sie als aktives sekretorisches Organ betrachtet. Ausgelöst durch Kontraktion sezerniert die Muskulatur regulatorische Myokine, die u. a. den sogenannten „Organ Cross-Talk“ vermitteln, die Kommunikation zwischen der Skelettmuskulatur und anderen Teilen des Organismus. Den Myokinen werden viele gesundheitsfördernde Effekte zugeschrieben. Sie wirken positiv auf den Metabolismus und unterdrücken Entzündungen.

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