Dtsch Med Wochenschr 2020; 145(04): 240-247
DOI: 10.1055/a-0974-9420
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© Georg Thieme Verlag KG Stuttgart · New York

Infekt-assoziierte Glomerulonephritiden

Infections-associated Glomerulonephritis
Martin Kimmel
Further Information

Publication History

Publication Date:
18 February 2020 (online)

Abstract

Glomerulonephritis, secondary to bacterial, or, more rarely, viral or parasitic infections, is called infection-associated. The epidemiology of infection-associated glomerulonephritis has changed in recent decades. For a long time, the classic form has been acute poststreptococcal glomerulonephritis (APGN), but in developed countries its incidence has declined sharply. However, there is an increase in staphylococcal associated glomerulonephritis (SAGN). The clinical manifestations of APGN and SAGN are different: APGN typically presents with a glomerulonephritis after an infectious latency period (post-infectious), while SAGN typically shows an immune complex glomerulonephritis concomitant with infection (para-infectious). SAGN often presents with an occult infections in older patients with multiple comorbidities.

Glomerulonephritiden, die sekundär bei meist bakteriellen, seltener bei viralen oder parasitären Infektionen auftreten, werden als Infekt-assoziiert bezeichnet. Die Epidemiologie hat sich in den letzten Jahrzehnten gewandelt. Der klassische Vertreter war lange Zeit die akute Poststreptokokken-Glomerulonephritis, in westlichen Industrieländern handelt es sich heutzutage zumeist um Staphylokokken-assoziierte Glomerulonephritiden [1].

 
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