Schläfenlappenepilepsie

Pitt Niehusmann; Albert J. Becker

doi:10.1055/a-0998-0264

Nervenheilkunde, Table of Contents

Nervenheilkunde 2019; 38(12): 929-935
DOI: 10.1055/a-0998-0264

Schwerpunkt

Schläfenlappenepilepsie

Neuropathologiespektrum revisitedTemporal lobe epilepsy

Pitt Niehusmann

¹Abteilung für Neuro-/Pathologie, Universitätsklinikum Oslo

,

Albert J. Becker∗

²Sektion für Translationale Epilepsieforschung am Institut für Neuropathologie, Universitätsklinikum Bonn

› Author Affiliations

Abstract

ZUSAMMENFASSUNG

Die Schläfenlappenepilepsie stellt die häufigste fokale Epilepsieform dar. Trotz etablierter Pathologiemuster ergaben sich zuletzt grundlegende Innovationen im Hinblick sowohl auf erworbene Epilepsien mit hippocampalem Ursprung als auch bei fokalen kortikalen Dysplasien und epilepsieassoziierten, oft glioneuronalen Tumoren. Besondere Erwähnung finden Verbesserungen des molekulargenetischen Verständnisses der Erkrankungen.

ABSTRACT

Temporal lobe epilepsy represents the most frequent form of focal epilepsy. Despite established pathology patterns fundamental innovations concerning acquired epilepsies affecting the hippocampal formation as well as with respect to focal cortical dysplasias and epilepsy-associated, often glioneuronal tumors have emerged. Particular emphasis of this article will be on the improvement of the molecular-genetic understanding of these diseases.

Schlüsselwörter

Hippocampussklerose - Dysplasie - LEA-Tumor

Key words

Hippocampal sclerosis - dysplasia - LEA tumor

Full Text

References

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