Author commentary on Gaius Longcroft-Wheaton et al.

Gaius Longcroft-Wheaton et al. A feasibility trial of Acetic acid-targeted Biopsies versus nontargeted quadrantic biopsies during BArrett’s surveillance: the ABBA trial

Study assessing the feasibility of initiating a large crossover trial on the use of acetic acid-targeted biopsies in Barrett’s surveillance. Qualitative analysis showed this was acceptable to both patients and physicians. Initial results in 200 patients suggest that acetic acid chromoendoscopy can reduce the number of biopsies by almost a factor of 10 compared with the Seattle protocol, and a further large definitive trial is now warranted.