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Allgemeine Homöopathische Zeitung 2020; 265(02): 26-33
DOI: 10.1055/a-1103-1005
Praxis

Symbioselenkung bei homöopathisch behandelten Patienten mit komplexen Pathologien

Erfahrungsberichte
Ina Chammah
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Zusammenfassung

Nach einer Einführung in einige Schlüsselfunktionen des Mikrobioms wird die heute mögliche Diagnostik und Therapie des Mikrobioms zusammenfassend beschrieben. Anhand von 3 Kasuistiken wird die sogenannte „Symbioselenkung“ dargestellt und wie sie während oder vor der homöopathischen Behandlung komplexer Krankheitsbilder den Therapieverlauf positiv beeinflussen kann. Dabei kann gezeigt werden, dass neben Darmbeschwerden auch auf psychische Veränderungen, Allergien, autoimmune Geschehen und Hauterkrankungen positiver Einfluss genommen werden kann.

Abstract

After an introduction to some key functions of the microbiome, the diagnosis and therapy of the microbiome, which is possible today, is summarized. Based on 3 case reports, the rectification of symbiosis is presented and it is shown how it can positively influence the course of therapy during or before the homeopathic treatment of complex diseases. It is shown that in addition to bowel problems, also mental changes, allergies, autoimmune and skin diseases can be positively affected.

Schlüsselworte

Microbiome - Symbioselenkung - komplexe Pathologie - Allergie - Autoimmunerkrankung - Hauterkrankung

Keywords

Microbiome - symbiosis - complex disease - allergy - autoimmune disease - skin disease


Publication History

Article published online:
20 March 2020

© Georg Thieme Verlag KG
Stuttgart · New York

 

  • Literatur

  • 1 Autenrieth IB. Die Ökologie der humanen Darmflora: Physiologische und pathophysiologische Aspekte. Journal für Ernährungsmedizin 2000; 2 (04) : 6-9
    Google Scholar
  • 2 Autenrieth IB. Die Ökologie der humanen Darmflora: physiologische und pathologische Aspekte. Journal für Gastroenterologische und Hepatologische Erkrankungen 2003; 1 (01) : 14-17
    Google Scholar
  • 3 Boem F, Amedei A. Healthy axis: Towards an integrated view of the gut-brain health. World Journal of Gastroenterology 2019; 25 (29) : 3838-3841
    CrossrefPubMedGoogle Scholar
  • 4 Breyner N. et al. Microbial Anti-Inflammatory Molecule (MAM) from Faecalibacterium prausnitzii shows a protective effect on DNBS and DSS-induced colitis model in mice through inhibition of NF-κB Pathway. Frontiers in Microbiology 2017. DOI: 10.3389/fmicb.2017.00114
    CrossrefPubMedGoogle Scholar
  • 5 Bundesinstitut für Arzneimittel und Medizinprodukte. Im Internet:. www.bfarm.de/SharedDocs/Risikoinformationen/Pharmakovigilanz/DE/RV_STP/s-z/symbioflor2.html; Stand: 21.01.2020
  • 6 Consortium, Integrative HMP (iHMP) Research Network. The Integrative Human Microbiome Project. Nature 2019; 569 (7758): 641-648
    CrossrefPubMedGoogle Scholar
  • 7 Corrêa-Oliveira R. et al. Regulation of immune cell function by short-chain fatty acids. Clinical and Translational Immunology 2016; 5 (04) : e73
    PubMedGoogle Scholar
  • 8 Enck P. et al. A mixture of Escherichia Coli (DSM 17252) and Enterococcus Faecalis (DSM 16440) for treatment of the Irritable Bowel Syndrome: A randomized controlled trial with primary care physicians. Neurogastroenterol Motil 2008; 20 (10) : 1103-1109
    CrossrefPubMedGoogle Scholar
  • 9 Enck P. et al. Randomized controlled treatment trial of Irritable Bowel Syndrome with a probiotic E.-coli preparation (DSM17252) compared to placebo. Z Gastroenterol 2009; 47 (02) : 209-214
    Article in Thieme ConnectPubMedGoogle Scholar
  • 10 Fasano A. Intestinal permeability and its eegulation by Zonulin: Diagnostic and therapeutic implications. Clin Gastroenterol Hepatology 2012; 10 (10) : 1096-1100
    Google Scholar
  • 11 Gill SR. et al. Metagenmic analysis of the human distal gut microbiome. Science 2011; 312 (5778): 1355-1359
    Google Scholar
  • 12 Goeser F. Mikrobiomforschung: Wie körpereigene Keime als „Superorgan“ agieren. Deutsches Ärzteblatt 2012; 109: A1317-A1318
    Google Scholar
  • 13 Hahne D. Mikrobiom und intestinale Gesundheit: Eine hohe Diversität von Darmbakterien ist günstig. Deutsche Ärzteblatt 2017; 114 (05) : A222-A223
    Google Scholar
  • 14 Hahnemann SCF. Organon der Heilkunst. Berg am Starnberger See: O.-Verlag; 1985: 63
    PubMedGoogle Scholar
  • 15 Halmos EP, Mack A, Gibson PR. Review article: Emulsifiers in the food supply and implications for gastrointestinal disease. Aliment Pharmacol Ther 2018; 49 (01) : 41-50
    Google Scholar
  • 16 Holder MK. et al. Dietary emulsifiers consumption alters anxiety-like and social-related behaviors in mice in a sex-dependent manner. International Journal of Scientific Reports 2019; 9: 172
    CrossrefPubMedGoogle Scholar
  • 17 Holota Y. et al. The long-term consequences of antibiotic therapy: Role of colonic short-chain fatty acids (SCFA) system and intestinal barrier integrity. PloS One 2019; 14 (08) : e020642
    Google Scholar
  • 18 Integrative HMP (iHMP) Research Network Consortium. Dynamic analysis of microbiome-host omics profiles during periods of human health and disease. Cell Host Microbe 2014; 16 (03) : 276-289
    CrossrefPubMedGoogle Scholar
  • 19 Johansson ME, Hansson GC. Immunological aspects of intestinal mucus and mucins. Nature reviews Immunology 2016; 16 (10) : 639-649
    CrossrefPubMedGoogle Scholar
  • 20 Lamb CA, Kennedy NA, Raine T. Gastroenterology consensus guidelines on the management of inflammatory bowel disease in adults. Gut 2019; 68 (Suppl3): s1-s106
    CrossrefPubMedGoogle Scholar
  • 21 Lau S. et al. Oral application of bacterial lysate in infancy decreases the risk of atopic dermatitis in children with parent an a randomized, placebo-controlled trial. Journal of Allergy and Clinical Immunology 2012; 129 (04) : 1040-1047
    CrossrefPubMedGoogle Scholar
  • 22 LeBlanc JG. et al. Bacteria as vitamin suppliers to their host: A gut microbiota perspective. Current Opinion in Biotechnology 2013; 24 (02) : 160-168
    CrossrefPubMedGoogle Scholar
  • 23 Ledochowski M. et al. Fructose- and sorbitol-reduced diet improves mood and gastrointestinal disturbances in fructose malabsorbers. Scandinavian Journal of Gastroenterology 2000; 35: 1048-1052
    CrossrefPubMedGoogle Scholar
  • 24 Mafarlane S, Macfarlane GT. Regulation of short-chain fatty acid production. The Proceedings of the Nutrition Society 2003; 62: 67-72
    CrossrefPubMedGoogle Scholar
  • 25 McCormick BJJ. et al. Intestinal permeability and inflammation mediate the association between nutrient density of complementary foods and biochemical measures of micronutrient status in young children: Results from the MAL-ED Study. American Journal of Clinical Nutrition 2019; 110: 1015-1025
    CrossrefPubMedGoogle Scholar
  • 26 Nobel YR. et al. Metabolic and metagenomic outcomes from early-life. Nat Commun 2015 6. 7486
    PubMedGoogle Scholar
  • 27 Palleja A, Mikkelsen K, Forslund S. et al. Recovery of gut microbiota of healthy adults following antibiotic exposure. Nature microbiology 2018; 3: 1255-1265
    CrossrefPubMedGoogle Scholar
  • 28 Quevrain E. et al. Identification of an anti-inflammatory protein from Faecalibacterium prausnitzii, a commensal bacterium deficient in Crohn’s disease. Gut 2016; 65: 415-425
    CrossrefPubMedGoogle Scholar
  • 29 Riedel C, Foata F. et al. Anti-inflammatory effects of bifidobacteria by inhibition of LPS-induced NF-kappaB activation. World Journal of Gastroenterology 2006; 12: 3729-3735
    CrossrefPubMedGoogle Scholar
  • 30 Schütz B, Hofmann H, Deutschbein R. Die intestinale Mikrobiota in der Onkologie. Deutsche Zeitschrift für Onkologie; Komplementäre und integrative Ansätze für die Praxis 2019: 108-112
    PubMedGoogle Scholar
  • 31 Sicard JF, Le Bihan G, Vogeleer P. Interactions of intestinal bacteria with components of the intestinal mucus. Frontiers in Cellular and Infection Microbiology. 2017 . DOI: 10.3389/fcimb.2017.00387
    CrossrefPubMedGoogle Scholar
  • 32 Sivaprakasam S. et al. Short-chain fatty acid transporters: Role in colonic homeostasis. Comprehensive Physiology 2017; 8: 299-314
    PubMedGoogle Scholar
  • 33 Strygler B. et al. Alpha 1-antitrypsin excretion in stool in normal subjects and in patients with gastrointestinal disorders. Gastroenterology 1990; 99: 1380-1387
    CrossrefPubMedGoogle Scholar
  • 34 Sturgeon C, Fasano A. Zonulin, a regulator of epithelial and endothelial barrier functions, and its involvement in chronic inflammatory diseases. Tissue Barriers 2016; 4 (04) : e1251384
    CrossrefPubMedGoogle Scholar
  • 35 The Human Microbiome Project Consortium. Structure, function and diversity of the healthy human microbiome. Nature 2012; 486: 207-214
    CrossrefPubMedGoogle Scholar
  • 36 US National Library, of Med. Nat. Inst. of Health. Pubmed.gov. Im Internet:. https://pubmed.ncbi.nlm.nih.gov/?term=intestinal+microbiome ; Stand: 21.01.2020
  • 37 Varea V, de Carpi JM. et al. Malabsorption of carbohydrates and depression in children and adolescents. Journal of Pediatric Gastroenterology and Nutrition 2005; 40: 561-565
    CrossrefPubMedGoogle Scholar
  • 38 Ventura M, Le Blanc JG, Milani C. et al. Bacteria as vitamin suppliers to their host: A gut microbiota perspective. Current Opinion in Biotechnology 2013: 160-168
    PubMedGoogle Scholar
  • 39 Wrzosek L. et al. Bacteroides thetaiotaomicron and Faecalibacterium prausnitzii influence the production of mucus glycans and the development of goblet cells in the colonic epithelium of a gnotobiotic model rodent. BMC Biology 2013; 61: 11
    Google Scholar
  • 40 Zhou W. et al. Protective effects of bifidobacteria on intestines in newborn rats with necrotizing enterocolitis and its regulation on TLR2 and TLR4. Genetics and molecular research 2015 14. 11505-11514
    PubMedGoogle Scholar