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Exp Clin Endocrinol Diabetes 2021; 129(10): 776-778
DOI: 10.1055/a-1158-9214
Letter to the Editor

Exceptional Response of Nelson’s Syndrome to Pasireotide LAR in the Long-Term Follow-up of 9 Years

Sandra M. Fill
1   Urological Clinic und Poliklinik für Urologie, Munich
,
Kathrin H. Popp 
2   Medicover Neuroendocrinology Prof. Stalla and Colleagues, Munich
,
Günter K. Stalla   *
2   Medicover Neuroendocrinology Prof. Stalla and Colleagues, Munich
3   Medizinische Klinik und Poliklinik IV, Klinikum der Universität, Ludwig-Maximilians Universität München, Munich
,
Anastasia P. Athanasoulia-Kaspar
2   Medicover Neuroendocrinology Prof. Stalla and Colleagues, Munich
1   Urological Clinic und Poliklinik für Urologie, Munich
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* shared last authorship.




Publication History

Received: 18 February 2020
Received: 30 March 2020

Accepted: 07 April 2020

Article published online:
12 November 2020

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  • References

  • 1 Nelson DH, Meakin JW, Dealy JB. et al. ACTH-producing tumor of the pituitary gland. N Engl J Med 1958; 259: 161-164
    CrossrefPubMedSearch in Google Scholar
  • 2 Patel J, Eloy JA, Liu JK. Nelson’s syndrome: A review of the clinical manifestations, pathophysiology, and treatment strategies. Neurosurg Focus 2015; 38: E14
    CrossrefPubMedSearch in Google Scholar
  • 3 Kurowska M, Nowakowski A, Zieliński G. et al. Temozolomide-induced shrinkage of invasive pituitary adenoma in patient with Nelson’s Syndrome: A case report and review of the literature. Case Rep Endocrinol 2015; 2015: 623092
    PubMedSearch in Google Scholar
  • 4 Feelders RA, de Herder WW, Neggers SJ. et al. Pasireotide, a multi-somatostatin receptor ligand with potential efficacy for treatment of pituitary and neuroendocrine tumors. Drugs Today (Barc) 2013; 49: 89-103
    CrossrefPubMedSearch in Google Scholar
  • 5 de Bruin C, Pereira AM, Feelders RA. et al. Coexpression of dopamine and somatostatin receptor subtypes in corticotroph adenomas. J Clin Endocrinol Metab 2009; 94: 1118-1124
    CrossrefPubMedSearch in Google Scholar
  • 6 Lau D, Rutledge C, Aghi MK. Cushing’s disease: Current medical therapies and molecular insights guiding future therapies. Neurosurg Focus 2015; 38: E11
    CrossrefPubMedSearch in Google Scholar
  • 7 Katznelson L. Sustained improvements in plasma ACTH and clinical status in a patient with Nelson’s syndrome treated with pasireotide LAR, a multireceptor somatostatin analog. J Clin Endocrinol Metab 2013; 98: 1803-1807
    CrossrefPubMedSearch in Google Scholar
  • 8 Daniel E, Debono M, Caunt S. et al. A prospective longitudinal study of Pasireotide in Nelson’s syndrome. Pituitary 2018; 21: 247-255
    CrossrefPubMedSearch in Google Scholar