ABC5 – Internationale Konsensuskonferenz zum fortgeschrittenen Mammakarzinom, Lissabon, 16.11.2019 – Deutsche Expertengruppe kommentiert ABC5-Abstimmungsergebnisse

Michael Untch; Rachel Würstlein; Diana Lüftner; Renate Haidinger; Peter A. Fasching; Doris Augustin; Susanne Briest; Johannes Ettl; Frank Förster; Christian M. Kurbacher; Hans-Joachim Lück; Norbert Marschner; Lothar Müller; Volkmar Müller; Isabel Radke; Eugen Ruckhäberle; Iris Scheffen; Eva Schumacher-Wulf; Moritz Schwoerer; Dieter Steinfeld-Birg; Katja Ziegler-Löhr; Christoph Thomssen; Nadia Harbeck

doi:10.1055/a-1205-4313

Senologie - Zeitschrift für Mammadiagnostik und -therapie, Table of Contents

Senologie - Zeitschrift für Mammadiagnostik und -therapie 2020; 17(03): 173-186
DOI: 10.1055/a-1205-4313

Wissenschaftliche Arbeit

ABC5 – Internationale Konsensuskonferenz zum fortgeschrittenen Mammakarzinom, Lissabon, 16.11.2019 – Deutsche Expertengruppe kommentiert ABC5-Abstimmungsergebnisse^[1]

ABC5 International Consensus Conference on Advanced Breast Cancer, Lisbon, 16 November 2019 – Commentary by the German panel of experts on the ABC5 voting results

Michael Untch

¹Klinik für Gynäkologie und Geburtshilfe, Brustzentrum und Gynäkologisch-Onkologisches Zentrum, HELIOS-Klinikum Berlin-Buch, Berlin

,

Rachel Würstlein

²Brustzentrum und Comprehensive Cancer Center (CCC) München, Klinik und Poliklinik für Frauenheilkunde und Geburtshilfe, Universität München (LMU), München

,

Diana Lüftner

³Medizinische Klinik mit Schwerpunkt Hämatologie, Onkologie und Tumorimmunologie, Charité-Berlin, Campus Benjamin Franklin, Berlin

,

Renate Haidinger

⁴Brustkrebs Deutschland e. V.; Patientenvertreterin

,

Peter A. Fasching

⁵Universitätsfrauenklinik Erlangen, Comprehensive Cancer Center (CCC) Erlangen-EMN, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen

,

Doris Augustin

⁶Mammazentrum Ostbayern, DONAUISAR-Klinikum Deggendorf, Deggendorf

,

Susanne Briest

⁷Klinik und Poliklinik für Frauenheilkunde, Universitätsklinikum Leipzig, Leipzig

,

Johannes Ettl

⁸Frauenklinik und Poliklinik für Frauenheilkunde und Geburtshilfe, Klinikum rechts der Isar, München

,

Frank Förster

⁹Praxis für Gynäkologie und Geburtshilfe, Gynäkologische Onkologie und Palliativmedizin, Poliklinik gGmbH, Chemnitz

,

Christian M. Kurbacher

¹⁰Gynäkologie I (Gynäkologische Onkologie), Gynäkologisches Zentrum, Bonn-Friedensplatz, Bonn

,

Hans-Joachim Lück

¹¹Schwerpunktpraxis für Hämato-Onkologie, Hannover

,

Norbert Marschner

¹²Gemeinschaftspraxis für interdisziplinäre Onkologie und Hämatologie, Freiburg

,

Lothar Müller

¹³Onkologische Schwerpunktpraxis Leer-Emden-Papenburg, Leer, Emden, Papenburg

,

Volkmar Müller

¹⁴Universitätsfrauenklinik Hamburg-Eppendorf, Hamburg

,

Isabel Radke

¹⁵Brustzentrum, Universitätsklinikum Münster, Münster

,

Eugen Ruckhäberle

¹⁶Frauenklinik, der Heinrich-Heine-Universität, Düsseldorf

,

Iris Scheffen

¹⁷Brustzentrum am St.-Elisabeth-Krankenhaus GmbH, Köln

,

Eva Schumacher-Wulf

¹⁸Mamma Mia! Brustkrebs-Magazin, Kronberg

,

Moritz Schwoerer

¹⁹Frauenklinik, Klinikum Fürstenfeldbruck, Fürstenfeldbruck

,

Dieter Steinfeld-Birg

²⁰Gynäkologische Onkologie Augsburg, Augsburg

,

Katja Ziegler-Löhr

²¹Schwerpunktpraxis für Gynäkologische Onkologie, Köln, Köln

,

Christoph Thomssen

²²Universitätsklinik und Poliklinik für Gynäkologie, Martin-Luther-Universität, Halle an der Saale; ABC-Panel-Mitglied, ABC Scientific Committee Mitglied

,

Nadia Harbeck

²³Brustzentrum und Comprehensive Cancer Center (CCC) München, Universität München (LMU), München; ABC-Panel-Mitglied

› Author Affiliations

Abstract

Zusammenfassung

Vom 14. bis 16. November 2019 fand in Lissabon die fünfte internationale Konsensuskonferenz ABC5 (Advanced Breast Cancer Fifth Consensus) zu Diagnostik und Behandlung des fortgeschrittenen Mammakarzinoms statt. Ziel ist es, die Behandlung der Patientinnen mit fortgeschrittenem Mammakarzinom weltweit auf evidenzbasierter Grundlage zu standardisieren und sicherzustellen, dass Patientinnen überall auf der Welt adäquat behandelt werden und Zugang zu neuen Therapien erhalten. Ein inhaltlicher Schwerpunkt lag dieses Jahr auf neuen Entwicklungen und Studienergebnissen beim fortgeschrittenen Mammakarzinom sowie der Präzisionsmedizin. Zudem ist die Zusammenarbeit mit den Patientenvertreterinnen aus aller Welt ein wichtiges Anliegen der ABC-Konferenz, weshalb in dem international zusammengesetzten ABC-Panel auch Patientenvertreterinnen sind. Im vorliegenden Manuskript werden die Abstimmungsergebnisse der ABC5-Panelisten vor Ort durch eine Arbeitsgruppe deutscher Brustkrebsexperten für den Therapiealltag in Deutschland kommentiert. Der Kommentierung liegen die Empfehlungen der Arbeitsgemeinschaft Gynäkologische Onkologie (AGO), Kommission „Mamma“, zugrunde. Sie erscheint sinnvoll, da in den ABC-Konsensus auch länderspezifische Besonderheiten einfließen.

Abstract

The Advanced Breast Cancer Fifth International Consensus Conference (ABC5) which focuses on the diagnosis and treatment of advanced breast cancer was held in Lisbon on November 14–16, 2019. The aim of the conference is to standardize the treatment of advanced breast cancer worldwide using evidence-based data and to ensure that patients with advanced breast disease anywhere in the world are treated appropriately and have access to the latest therapies. This year, the emphasis was on new developments and study results from patients with advanced breast cancer as well as precision medicine. The collaboration with patient advocates from all over the globe is also an important goal of the ABC Conference, which is why the international ABC panel also included a number of patient advocates. We present a commentary on the voting results of the ABC5 panelists in Lisbon by a working group of German breast cancer specialists together with the implications for routine clinical care in Germany. The commentary is based on the recommendations of the Breast Commission of the German Gynecological Oncology Working Group (AGO). This commentary is useful, it includes country-specific features for the ABC consensus.

Schlüsselwörter

ABC5‑Konsensus - fortgeschrittenes Mammakarzinom - Präzisionsmedizin - Studiendaten 2019

Key words

ABC5 consensus - advanced breast cancer - precision medicine - 2019 study data

Full Text

References

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ABC5 – Internationale Konsensuskonferenz zum fortgeschrittenen Mammakarzinom, Lissabon, 16.11.2019 – Deutsche Expertengruppe kommentiert ABC5-Abstimmungsergebnisse[1]

ABC5 – Internationale Konsensuskonferenz zum fortgeschrittenen Mammakarzinom, Lissabon, 16.11.2019 – Deutsche Expertengruppe kommentiert ABC5-Abstimmungsergebnisse^[1]