Successful treatment of anastomotic leakage by endoscopic stenting after esophageal atresia repair in an infant

A 1-day-old infant was admitted with dyspnea and increased oral secretion following birth. Chest X-ray obtained after failure of nasogastric tube placement revealed tube curling in the upper esophagus. The diagnosis was esophageal atresia with tracheoesophageal fistula, requiring thoracoscopic repair of the fistula and atresia on Day 3 after birth.

He resumed feeding with milk, but turbid fluid was observed in the chest tube 1 week after the surgery. Anastomotic leakage was considered, and parenteral nutrition and antibiotic therapy were initiated. He experienced intermittent fever, and esophagography revealed contrast medium leakage from the anastomotic site on hospital Day 50 ([Fig. 1], arrows).

Fig. 1 Esophagography revealed contrast leakage from the chest tube (arrows).

Endoscopic therapy was performed due to lack of clinical improvement after conservative medical therapy. Severe stenosis with ulceration over the anastomosis was observed using an ultra-thin endoscope ([Fig. 2 a], [Video 1]). Argon plasma coagulation was performed for suspected fistula tract, and a fully covered biliary metal stent (8 mm × 6 cm) was placed over the fistula ([Fig. 2 b]), which was removed 2 weeks later. The stenosis improved and the anastomotic mucosa healed ([Fig. 2 c]). Follow-up esophagography disclosed no contrast leakage, and the patient’s condition improved; he was initiated on an oral diet and discharged on hospital Day 93.

Fig. 2 Endoscopic views. a Stenosis and ulceration over the anastomosis site. b View after successful placement of a covered biliary stent over the anastomosis. c View after removal of the stent.

Video 1 Successful treatment of anastomotic leakage after esophageal atresia repair by endoscopic stenting in an infant.

Anastomotic stricture and leakage are the two most frequent complications after esophageal atresia repair [1] [2] [3]. The management of minor esophageal leakage is mainly supportive, and surgery is reserved for those cases refractory to medical therapy. An esophageal metal stent is used to treat either esophageal stricture or leakage in adults but the experience is lacking in pediatric patients [2]. Because of the absence of manufactured, age-related stents, we utilized a biliary stent as an alternative in order to successfully treat this difficult disease.

Endoscopy_UCTN_Code_TTT_1AO_2AI

Competing interests

The authors declare that they have no conflict of interest.

Acknowledgment

The authors received funding from the Changhua Christian Hospital (105-IRP-CCH-009, 106-CCHIRP-030 and 108-CCH-IRP-018) for this manuscript.

• References

• 1 Manfredi MA. Endoscopic management of anastomotic esophageal strictures secondary to esophageal atresia. Gastrointest Endosc Clin N Am 2016; 26: 201-219
• 2 Lange B, Sold M, Kähler G. et al. Experience with fully covered self-expandable metal stents for anastomotic stricture following esophageal atresia repair. Dis Esophagus 2018; 31: 1-7
• 3 Chittmittrapap S, Spitz L, Kiely EM. et al. Anastomotic leakage following surgery for esophageal atresia. J Pediatr Surg 1992; 27: 29-32

Publication History

Article published online:
20 August 2020