Sekundäre Peritonitis

Hanno Nieß; Jens Werner

doi:10.1055/a-1249-4754

Intensivmedizin up2date, Table of Contents

Intensivmedizin up2date 2021; 17(04): 493-510
DOI: 10.1055/a-1249-4754

Operative Intensivmedizin

Sekundäre Peritonitis

Bedeutung von klinischer Diagnose und zeitnaher chirurgischer Intervention

Hanno Nieß

,

Jens Werner

Abstract

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Die sekundäre Peritonitis bleibt trotz aller diagnostischen und therapeutischen Fortschritte ein Krankheitsbild mit relevanter Mortalität. Die Schlüsselelemente in der erfolgreichen Behandlung sind die schnelle Diagnosestellung, adäquate Volumengabe, frühe Einleitung einer adäquaten antibiotischen Therapie, rasche und effektive operative Kontrolle des septischen Fokus und die wiederholte Bewertung des klinischen Ansprechens und ggf. Anpassung des klinischen Managements.

Schlüsselwörter

Peritonitis - Sepsis - komplizierte intraabdominelle Infektion - Perforation - Darmischämie

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References

Literatur
1 Koperna T, Schulz F. Prognosis and treatment of peritonitis. Do we need new scoring systems?. Arch Surg 1996; 131: 180-186
2 Anaya DA, Nathens AB. Risk factors for severe sepsis in secondary peritonitis. Surg Infect (Larchmt) 2003; 4: 355-362
3 Sartelli M, Catena F, Ansaloni L. et al. Complicated intra-abdominal infections in Europe: a comprehensive review of the CIAO study. World J Emerg Surg 2012; 7: 36
4 Gauzit R, Pean Y, Barth X. et al. Epidemiology, management, and prognosis of secondary non-postoperative peritonitis: a French prospective observational multicenter study. Surg Infect (Larchmt) 2009; 10: 119-127
5 Ross JT, Matthay MA, Harris HW. Secondary peritonitis: principles of diagnosis and intervention. BMJ 2018; 361: k1407
6 van Baal JO, Van de Vijver KK, Nieuwland R. et al. The histophysiology and pathophysiology of the peritoneum. Tissue Cell 2017; 49: 95-105
7 Takeuchi O, Akira S. Pattern recognition receptors and inflammation. Cell 2010; 140: 805-820
8 Serhan CN. Pro-resolving lipid mediators are leads for resolution physiology. Nature 2014; 510: 92-101
9 Schein M, Wittmann DH, Holzheimer R. et al. Hypothesis: compartmentalization of cytokines in intraabdominal infection. Surgery 1996; 119: 694-700
10 Gajic O, Urrutia LE, Sewani H. et al. Acute abdomen in the medical intensive care unit. Crit Care Med 2002; 30: 1187-1190
11 Acharya A, Markar SR, Ni M. et al. Biomarkers of acute appendicitis: systematic review and cost-benefit trade-off analysis. Surg Endosc 2017; 31: 1022-1031
12 Tan JP, Barazanchi AW, Singh PP. et al. Predictors of acute diverticulitis severity: A systematic review. Int J Surg 2016; 26: 43-52
13 Grupp K, Groteluschen R, Uzunoglu FG. et al. C-Reactive Protein in the Prediction of Localization of Gastrointestinal Perforation. Eur Surg Res 2019; 60: 179-185
14 Rau BM, Frigerio I, Buchler MW. et al. Evaluation of procalcitonin for predicting septic multiorgan failure and overall prognosis in secondary peritonitis: a prospective, international multicenter study. Arch Surg 2007; 142: 134-142
15 Singh PP, Zeng IS, Srinivasa S. et al. Systematic review and meta-analysis of use of serum C-reactive protein levels to predict anastomotic leak after colorectal surgery. Br J Surg 2014; 101: 339-346
16 Reinhart K, Karzai W, Meisner M. Procalcitonin as a marker of the systemic inflammatory response to infection. Intensive Care Med 2000; 26: 1193-1200
17 Ma L, Zhang H, Yin YL. et al. Role of interleukin-6 to differentiate sepsis from non-infectious systemic inflammatory response syndrome. Cytokine 2016; 88: 126-135
18 Lameris W, van Randen A, van Es HW. et al. Imaging strategies for detection of urgent conditions in patients with acute abdominal pain: diagnostic accuracy study. BMJ 2009; 338: b2431
19 Jancelewicz T, Vu LT, Shawo AE. et al. Predicting strangulated small bowel obstruction: an old problem revisited. J Gastrointest Surg 2009; 13: 93-99
20 Ferrada P, Callcut R, Bauza G. et al. Pneumatosis Intestinalis Predictive Evaluation Study: A multicenter epidemiologic study of the American Association for the Surgery of Trauma. J Trauma Acute Care Surg 2017; 82: 451-460
21 Montravers P, Blot S, Dimopoulos G. et al. Therapeutic management of peritonitis: a comprehensive guide for intensivists. Intensive Care Med 2016; 42: 1234-1247
22 Hawn MT, Canon CL, Lockhart ME. et al. Serum lactic acid determines the outcomes of CT diagnosis of pneumatosis of the gastrointestinal tract. Am Surg 2004; 70: 19-23 discussion 23–24
23 AWMF. S2k-Leitlinie: Kalkulierte parenterale Initialtherapie bakterieller Erkrankungen bei Erwachsenen. AWMF-Registernummer 082-006M; erstellt: 2019. Im Internet (Stand: 02.08.2021): https://www.awmf.org/uploads/tx_szleitlinien/082-006l_S2k_Parenterale_Antibiotika_2019-08.pdf
24 van Ruler O, Mahler CW, Boer KR. et al. Comparison of on-demand vs. planned relaparotomy strategy in patients with severe peritonitis: a randomized trial. JAMA 2007; 298: 865-872