Noam Peleg et al. Neutrophil to lymphocyte ratio and risk of neoplastic progression
in patients with Barrett’s esophagus
An analysis in 324 individuals with Barrett’s esophagus showed that a simple inflammation
marker, the peripheral blood neutrophil to lymphocyte ratio (NLR), was predictive
of progression to neoplasia. In particular, an NLR above 2.4 was associated with a
3-fold increase in progression to high grade dysplasia or adenocarcinoma during follow-up.
This finding was consistent even in patients with nondysplastic Barrett’s esophagus
at baseline.
