Therapie von intrakardialen Shunt-Vitien

Intrakardiale Shunt-Vitien sind die häufigsten angeborenen Herzfehler und belasten sowohl den rechten als auch linken Ventrikel und das Pulmonalgefäßsystem. Die Therapie sollte in der Kindheit rechtzeitig begonnen werden und auch Langzeitprobleme müssen erkannt und adäquat therapiert werden. Für die meisten Patienten mit einem intrakardialen Shunt-Vitium ist daher eine lebenslange spezialisierte kardiologische Betreuung erforderlich.

Schlüsselwörter

Shunt-Vitien - Herzfehler - angeboren - Säugling - Ventrikelseptumdefekt - Vorhofseptumdefekt

• Literatur

• 1 Schwedler G, Lindinger A, Lange PE. et al. Frequency and spectrum of congenital heart defects among live births in Germany: a study of the Competence Network for Congenital Heart Defects. Clin Res Cardiol 2011; 100: 1111-1117
• 2 Campbell M. Natural history of atrial septal defect. Br Heart J 1970; 32: 820-826
• 3 Brida M, Chessa M, Celermajer D. et al. Atrial septal defect in adulthood: a new paradigm for congenital heart disease. Eur Heart J 2022; 43: 2660-2671
• 4 Wilkinson JL. Haemodynamic calculations in the catheter laboratory. Heart 2001; 85: 113-120
• 5 Baumgartner H, De Backer J, Babu-Narayan SV. et al. 2020 ESC Guidelines for the management of adult congenital heart disease. Eur Heart J 2021; 42: 563-645
• 6 Humenberger M, Rosenhek R, Gabriel H. et al. Benefit of atrial septal defect closure in adults: impact of age. Eur Heart J 2011; 32: 553-560
• 7 Steele PM, Fuster V, Cohen M. et al. Isolated atrial septal defect with pulmonary vascular obstructive disease--long-term follow-up and prediction of outcome after surgical correction. Circulation 1987; 76: 1037-1042
• 8 Manes A, Palazzini M, Leci E. et al. Current era survival of patients with pulmonary arterial hypertension associated with congenital heart disease: a comparison between clinical subgroups. Eur Heart J 2014; 35: 716-724
• 9 Tadros VX, Asgar AW. Atrial septal defect closure with left ventricular dysfunction. EuroIntervention 2016; 12(Suppl.X): X13-X17
• 10 Brida M, Diller GP, Kempny A. et al. Atrial septal defect closure in adulthood is associated with normal survival in the mid to longer term. Heart 2019; 105: 1014-1019
• 11 Hansen JH, Duong P, Jivanji SGM. et al. Transcatheter Correction of Superior Sinus Venosus Atrial Septal Defects as an Alternative to Surgical Treatment. J Am Coll Cardiol 2020; 75: 12661278
• 12 Hansmann G, Koestenberger M, Alastalo TP. et al. 2019 updated consensus statement on the diagnosis and treatment of pediatric pulmonary hypertension: The European Pediatric Pulmonary Vascular Disease Network (EPPVDN), endorsed by AEPC, ESPR and ISHLT. J Heart Lung Transplant 2019; 38: 879-901
• 13 Butera G, Chessa M, Carminati M. Percutaneous closure of ventricular septal defects. Cardiol Young 2007; 17: 243-253
• 14 Carminati M, Butera G, Chessa M. et al. Transcatheter closure of congenital ventricular septal defect with Amplatzer septal occluders. Am J Cardiol 2005; 96: 52L-58L
• 15 Fischer G, Apostolopoulou SC, Rammos S. et al. The Amplatzer Membranous VSD Occluder and the vulnerability of the atrioventricular conduction system. Cardiol Young 2007; 17: 499-504
• 16 Haddad RN, Daou LS, Saliba ZS. Percutaneous closure of restrictive-type perimembranous ventricular septal defect using the new KONAR multifunctional occluder: Midterm outcomes of the first middle-eastern experience. Catheter Cardiovasc Interv 2020; 96: E295-E302
• 17 Karonis T, Scognamiglio G, Babu-Narayan SV. et al. Clinical course and potential complications of small ventricular septal defects in adulthood: Late development of left ventricular dysfunction justifies lifelong care. Int J Cardiol 2016; 208: 102-106
• 18 Heiberg J, Redington A, Hjortdal VE. Exercise capacity and cardiac function after surgical closure of ventricular septal defect – Is there unrecognized long-term morbidity?. Int J Cardiol 2015; 201: 590-594
• 19 Roos-Hesselink JW, Meijboom FJ, Spitaels SE. et al. Outcome of patients after surgical closure of ventricular septal defect at young age: longitudinal follow-up of 22–34 years. Eur Heart J 2004; 25: 1057-1062
• 20 Menting ME, Cuypers JA, Opic P. et al. The unnatural history of the ventricular septal defect: outcome up to 40 years after surgical closure. J Am Coll Cardiol 2015; 65: 1941-1951
• 21 Jacobs JP, Burke RP, Quintessenza JA. et al. Congenital Heart Surgery Nomenclature and Database Project: ventricular septal defect. Ann Thorac Surg 2000; 69: S25-S35