Endoscopic submucosal dissection (ESD) is the technique of choice for the resection
of large superficial colorectal lesions [1], but it can be technically challenging in some situations. For this reason, lesions
involving the appendiceal orifice have long been removed surgically. However, recent
findings have found that ESD is effective and safe in that situation [2]
[3], even for lesions deeply invading the appendiceal orifice (Toyonaga 3 lesions) with
the help of traction device [4]
[5].
Here we report the case of a 70-year-old woman with a history of appendectomy who
underwent a colonoscopy that revealed a granular lateral spreading tumor (LST-G) of
3 cm invading the previous site of the appendectomy (Toyonaga 3a) ([Fig. 1]). An ESD using a multi-intertwined loop device was chosen ([Video 1]). After circumferential mucosal incision around the lesion, the first loop of the
device was attached to one edge of the lesion with a hemostatic clip. Then a second
loop was attached to the opposite edge of the lesion. Then the entire device was attached
to the opposite colonic wall. The submucosal space was well exposed at the two edges
of the LST-G, allowing a safe dissection during the whole procedure with an en-bloc
resection ([Fig. 2], [Fig. 3]). The patient was discharged the day after without experiencing any adverse event.
The pathology report showed a high-grade dysplasia with a focus of intramucosal adenocarcinoma
that was completely resected by the ESD. Owing to the curative resection, an endoscopic
follow-up was decided.
Fig. 1 A granular lateral spreading tumor invading the previous site of appendectomy.
Video 1 Endoscopic submucosal dissection of a lateral spreading tumor involving the appendiceal
orifice using a multi-traction device.
Fig. 2 The submucosal space was well exposed at the two edges of the granular lateral spreading
tumor thanks to the multi-traction device.
Fig. 3 Lesion after resection.
This case highlights that ESD can be safely performed in the appendiceal orifice even
with a history of appendectomy. The use of a multi-traction device helped to obtain
very satisfying exposure of the submucosal space. A randomized control study evaluating
this device would be necessary to confirm this promising result.
Endoscopy_UCTN_Code_TTT_1AQ_2AJ
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