Malignant hilar biliary obstruction often requires multiple stents for biliary drainage [1]
[2]. However, deploying three or more self-expandable metal stents (SEMSs) is technically challenging [3]. The recently launched, novel uncovered SEMS with slim delivery system (Niti-S Large Cell SR Slim delivery; TaeWoong Medical, Seoul, South Korea) may be combined with a 6-mm balloon catheter (REN biliary dilation catheter; KANEKA, Osaka, Japan) to facilitate the deployment of multiple SEMSs [4]. Here, we report a successful endoscopic four-branched deployment of SEMSs using the stent-in-stent (SIS) method.
A 66-year-old man with metastatic hilar cholangiocarcinoma, who had been undergoing chemotherapy, was admitted to our hospital with acute cholangitis. Initially, 7 months previously, two plastic stents had been deployed for malignant hilar obstruction of Bismuth type 4 in the B2 and B8 bile duct segments above the sphincter of Oddi. However, owing to recurrent cholangitis and a liver abscess, a total of four plastic stents were deployed 4 months later in B2, B5, B6, and B8 ([Fig. 1]).
Fig. 1 Radiographic image showing four plastic stents deployed above the sphincter of Oddi in a patient with malignant hilar biliary obstruction.
A computed tomography scan on admission showed dysfunctional plastic stents and deterioration of his cancer ([Fig. 2]). We attempted to deploy four SEMSs using the SIS method ([Video 1]). First, after removing the plastic stents, we deployed the first and second SEMSs in B6 and B2 using the SIS method. After dilating the mesh of the SEMSs using a balloon catheter, we deployed the third SEMS in B8 using the SIS method. Finally, an attempt was made to deploy a SEMS in B5, but the catheter could not be passed through the mesh of the SEMS. Therefore, a balloon catheter was used to dilate the lumen and mesh of the SEMSs, and the fourth SEMS was then successfully deployed in B5 using the SIS method ([Fig. 3]). There were no adverse events such as stent occlusion during the 2 months before the patient’s death, which was due to his primary disease.
Fig. 2 Computed tomography image on admission showing biliary stent occlusion.
Video 1 Successful endoscopic four-branched deployment using the stent-in-stent method for malignant hilar biliary obstruction.
Fig. 3 Radiographic image showing the four self-expandable metal stents resulting from the successful endoscopic four-branched deployment using the stent-in-stent method.
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