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Osteologie 2022; 31(01): 73-74
DOI: 10.1055/a-1725-2083
DOI: 10.1055/a-1725-2083
Gesellschaftsnachrichten
Der diagnostische Stellenwert der Isocitrat-Dehydrogenase-Mutationen beim Chondrosarkom
Im Jahre 2008 wurden erstmalig durch Parsons et al. bei einer kleinen Gruppe von jungen Gliompatienten somatische Mutationen in dem Gen für das Enzym Isocitrat-Dehydrogenase IDH1 (Chromosom 2q33) entdeckt [1]. Wenig später folgte der Nachweis der IDH1-Mutation bei dem zentralen Chondrosarkom durch Amary und Kollegen [2].
Publication History
Article published online:
21 February 2022
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