Endoscopic ultrasonography-guided hepaticogastrostomy with parenchymal metal stent placement

Endoscopic ultrasonography-guided hepaticogastrostomy (EUS-HGS) is performed to create a biliary drainage route for malignant distal biliary obstruction during complicated endoscopic retrograde cholangiopancreatography [1] [2]. However, when EUS-HGS is performed in patients with cholangitis and ascites, metal stent placement may cause peripheral obstructive cholangitis ([Fig. 1 a]), while plastic stents may cause biliary peritonitis due to bile leakage into the ascites ([Fig. 1 b]) [3] [4]. To address this challenge, we implemented a novel EUS-HGS method of hepatic parenchymal metal stent placement with plastic stent in the bile duct ([Fig. 2]), which proved to be effective ([Video 1]).

Fig. 1 Stent placement in endoscopic ultrasonography-guided hepaticogastrostomy. a There is a risk of obstructive cholangitis if a metal stent is placed at the same site as previous stents. b There is a risk of bile peritonitis when only a plastic stent is placed. EUS, endoscopic ultrasound; MS, metal stent; PS, plastic stent.

Fig. 2 Hepatic parenchymal metal stent placement with plastic stent in the bile duct prevented obstructive cholangitis and biliary peritonitis. EUS, endoscopic ultrasound; MS, metal stent; PS, plastic stent.

Video 1 Endoscopic ultrasonography-guided hepaticogastrostomy with parenchymal metal stent placement and plastic stent placement in the bile duct.

Our patient was a 64-year-old woman with biliary and duodenal stents for relieving the obstruction of the distal bile duct and duodenum due to unresectable pancreatic cancer. She developed cholangitis due to biliary stent dysfunction ([Fig. 3]). We decided to perform EUS-HGS with hepatic parenchymal metal stent placement using a laser cut-type fully covered metal stent (LFCMS) along with plastic stent placement in the bile duct.

Fig. 3 Imaging findings before the procedure. a Computed tomography (CT) showing dilated intrahepatic bile duct, with multiple liver metastases and ascites due to pancreatic cancer. b CT showing occluded duodenal and distal bile duct stent.

After puncturing B3 with a 19-gauge needle using a convex ultrasound endoscope, a 0.025-inch guidewire was placed into the common bile duct, and a 6-mm balloon was used to dilate the fistula. Subsequently, the LFCMS (8 mm diameter, 8 cm length, X-Suit NIR Biliary Metallic Stent; Olympus Medical Systems, Tokyo, Japan) was deployed, with the stent end in the hepatic parenchyma slightly outside the bile duct, while being careful not to occlude the bile duct with the stent. After confirming the position of the metal stent by contrast to ensure that it was not in the bile duct, a 7-Fr plastic stent (TYPE IT; Gadelius Medical, Tokyo, Japan) was placed in the bile duct ([Fig. 4], [Fig. 5]). The patient’s clinical condition improved after the procedure.

Fig. 4 Endoscopic ultrasonography (EUS)-guided hepaticogastrostomy with parenchymal metal stent placement. a EUS image: B3 (arrowheads) was punctured using a fine-needle aspiration (FNA) needle. b Fluoroscopic image: B3 was punctured using an FNA needle. c EUS image: a laser cut-type fully covered metal stent (arrow) was deployed in the hepatic parenchyma. Arrowheads indicate the bile duct wall (B3). d Fluoroscopic image: the metal stent deployed from the scope in the hepatic parenchyma.

Fig. 5 Plastic stent placement in the bile duct. a Fluoroscopic image: a plastic stent was placed in the bile duct. b Endoscopic image after stent placement. c Three-dimensional reconstruction.

The LFCMS is retained in place more easily than the braided-type metal stent. Therefore, LFCMS was considered suitable for this EUS-HGS method in a patient with cholangitis and ascites.

Endoscopy_UCTN_Code_TTT_1AS_2AD

Competing interests

The authors declare that they have no conflict of interest.

Acknowledgement

This work was supported in part by The National Cancer Center Research and Development Fund (31-A-13) and (2021-S-5).

• References

• 1 Dumonceau JM, Tringali A, Papanikolaou IS. et al. Endoscopic biliary stenting: indications, choice of stents, and results: European Society of Gastrointestinal Endoscopy (ESGE) Clinical Guideline – updated October 2017. Endoscopy 2018; 50: 910-930
• 2 Leung Ki EL, Napoleon B. Endoscopic ultrasound-guided biliary drainage: a change in paradigm?. World J Gastrointest Endosc 2019; 11: 345-353
• 3 Khan MA, Akbar A, Baron TH. et al. Endoscopic ultrasound-guided biliary drainage: a systematic review and meta-analysis. Dig Dis Sci 2016; 61: 684-703
• 4 Nakai Y, Sato T, Hakuta R. et al. Long-term outcomes of a long, partially covered metal stent for EUS-guided hepaticogastrostomy in patients with malignant biliary obstruction (with video). Gastrointest Endosc 2020; 92: 623-631

Publication History

Article published online:
07 March 2022