Kavernöse nichttuberkulöse Mykobakteriose der Lunge durch M. heckeshornense bei einem HIV-infizierten Patienten

Zusammenfassung

Bisher wurden nur 21 Fälle einer klinischen Infektion mit M. heckeshornense beim Menschen berichtet, nachdem die seltene Spezies erstmals im Jahr 2000 beschrieben wurde. Wir diskutieren Diagnose und Therapie eines weiteren Falles dieser seltenen atypischen Mykobakteriose bei einem immunsupprimierten Patienten [1].

Abstract

Since we first described Mycobacterium heckeshornense, a rare species of mycobacteria in 2000, only 21 cases of infection with this mycobacterium have been described in humans. We relate the diagnosis and therapy of another case of this uncommon nontuberculous mycobacterium in an immune-suppressed patient.

Schlüsselwörter

Atypische Mykobakteriose - Kavernöse Lungenerkrankung - Opportunistische Infektionen - Seltene Lungeninfektion

Keywords

Nontuberculous mycobacteria - cavernous lung disease - opportunistic infection - rare lung infection

• Literatur

• 1 Roth A, Reischl U, Schoenfeld N. et al. Mycobacterium heckeshornense sp. nov., a new pathogenic slowly growing Mycobacterium sp. causing cavitary lung disease in an immunocompetent patient. J Clin Microbiol 2000; 38: 4102-4107
• 2 National Committee for Clinical Laboratory Standards. Susceptibility testing of mycobacteria, nocardiae, and other aerobic actinomycetes: approved standard. Clinical and Laboratory Standards Institute document M24-A. Wayne (PA): The Committee; 2003
• 3 Schoenfeld N, Haas W, Richter E. et al. Recommendations of the German Central Committee against Tuberculosis (DZK) and the German Respiratory Society (DGP) for the Diagnosis and Treatment of Non-tuberculous Mycobacterioses. Pneumologie 2016; 70: 250-276
• 4 Schönfeld N. Perspectives on antibiotic treatment of NTM pulmonary disease, Ch. 14. In: Aliberti S, Chalmers JD, Pletz MW. Anti-infectives and the Lung (ERS Monograph). Sheffield: European Respiratory Society; 2017: 1-8
• 5 Van Hest R, van der Zanden A, Boeree M. et al. Mycobacterium heckeshornense infection in an immunocompetent patient and identification by 16S rRNA sequence analysis of culture material and a histopathology tissue specimen. J Clin Microbiol 2004; 42: 4386-4389
• 6 Godreuil S, Marchandin H, Terru D. et al. Mycobacterium heckeshornense tenosynovitis. Scand J Infect Dis 2006; 38: 1098-1101
• 7 Kazumi Y, Sugawara I, Wada M. et al. Microbiologically identified isolates of Mycobacterium heckeshornense in two patients. Kekkaku 2006; 81: 603-607
• 8 Jaureguy F, Ioos V, Marzouk P. et al. Mycobacterium heckeshornense: an emerging pathogen responsible for a recurrent lung infection. J Infect 2007; 54: 33-35
• 9 Hisamoto A, Ozaki S, Sakugawa M. et al. A possible case of pulmonary infection due to Mycobacterium heckenshornense [Japanese]. Nihon Kokyuki Gakkai Zasshi 2008; 46: 1019-1023
• 10 Elyousfi AA, Leiter JR, Goytan MJ. et al. Mycobacterium heckeshornense lumbar spondylodiskitis in a patient with rheumatoid arthritis receiving etanercept treatment. J Rheumatol 2009; 36: 2130-2131
• 11 McBride SJ, Taylor SL, Pandey SK. et al. First case of Mycobacterium heckeshornense lymphadenitis. J Clin Microbiol 2009; 47: 268-270
• 12 Chan WW, Murray MC, Tang P. et al. Mycobacterium heckeshornense peritonitis in a peritoneal dialysis patient: a case report and review of the literature. Clin Microbiol Infect 2011; 17: 1262-1264
• 13 Ahmed RA, Miedzinski LJ, Shandro C. Mycobacterium heckeshornense infection in HIV-infected patient. Emerg Infect Dis 2010; 16: 1801-1803
• 14 Ustinova V, Smirnova T, Varlamov D. et al. Draft Genome Sequence of a Mycobacterium heckeshornense Clinical Isolate. Genome Announc 2018; 6
• 15 Morimoto K, Kazumi Y, Maeda S. et al. Mycobacterium heckeshornense lung infection that was diagnosed as Mycobacterium xenopi disease by DNA-DNA hybridization (DDH). Intern Med 2011; 50: 1251-1253
• 16 Carpenter RJ, Graf PC. Pottʼs disease? AIDS-associated Mycobacterium heckeshornense spinal osteomyelitis and diskitis. J Clin Microbiol 2015; 53: 716-718
• 17 Coitinho C, Greif G, van Ingen J. et al. First case of Mycobacterium heckeshornense cavitary lung disease in the Latin America and Caribbean region. New Microbes New Infect 2015; 9: 63-65
• 18 Yokoyama A, Kage H, Ohama Y. et al. Mycobacterium heckeshornense lung infection diagnosed by matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS). J Infect Chemother 2018; 24: 763-765
• 19 Kurosaki F, Yoshimoto T, Nakayama M. et al. Pulmonary Mycobacterium heckeshornense infection in a healthy woman. J Infect Chemother 2018; 24: 483-486
• 20 Douiri N, Lefebvre N, Hansmann Y. et al. Relapsing Pott disease caused by Mycobacterium heckeshornense in a well-controlled HIV-infected patient. Med Mal Infect 2018; 48: 157-158
• 21 Howell D, Galen BT. Recurrent rheumatoid pleural effusions complicated by Mycobacterium heckeshornense infection. Respir Med Case Rep 2018; 25: 333-335
• 22 Nicolás-de Blas R, Garijo-Bufort M, Nebreda-Mayoral T. et al. Synovitis due to Mycobacterium heckeshornense in a patient with rheumatoid arthritis and treatment with infliximab. Enferm Infecc Microbiol Clin 2020;
• 23 Iitoh ETominaga M, Okamoto M. et al. A case of pulmonary Mycobacterium heckeshornense infection in a healthy Japanese man. Respir Med Case Resp 2020; 30: 101093
• 24 Elze J, Grammel L, Richter E et. al. First description of Mycobacterium heckeshornense infection in a feline immunodeficiency virus-positive cat. Feline Med Surg 2013; 15: 1141-1144
• 25 van Ingen J, Wisselink HJ, van Solt-Smits CB. et al. Isolation of mycobacteria other than Mycobacterium avium from porcine lymph nodes. Vet Microbiol 2010; 144: 250-253