Correction: Letrozole vs. Placebo Pretreatment in the Medical Management of First Trimester Missed Miscarriage: a Randomized Controlled Trial

Erratum

Letrozole vs. Placebo Pretreatment in the Medical Management of First Trimester Missed Miscarriage: a Randomized Controlled Trial
Haitham A. Torky, Heba Marie, ElSayed ElDesouky, Samy Gebreel, Osama Raslan, Asem A. Moussa, Ali M. Ahmad, Eman Zain, Mohamed N. Mohsen
Geburtsh Frauenheilk 2018; 78: 63–69
doi:10.1055/s-0043-122499

“Material and Methods”

Under the heading “Randomization and blinding” the sentence should read in full: Concealment was achieved using opaque envelopes, to blind the pysicians, while to blind the patients, the placebo tablet was methylcellulose resembling letrozole in shape.

“Results”

In the 1st paragraph, the last sentence correctly reads: There were no significant differences in age and gestational age between the two groups ([Table 1]).

Under the heading “Comparison of gravidity”, the p-value has been corrected in the last sentence of the 1st paragraph. Correct is: p = 0.742.

Under the heading “Comparison of previous cesarean sections”, the p-value has been corrected in the penultimate sentence. Correct is: p = 0.117.

[Table 1] has been corrected. Correct is:

Table 1 Comparison of demographic data.

Demographic data	Group 1 (placebo)	Group 2 (letrozole)	p-value
Age			0.863
Mean ± SD Range	26.62 ± 4.30 19 – 40	26.52 ± 3.87 19 – 35
Body mass index			0.0163
Mean ± SD Range	25.81 ± 2.7 16.53 – 33.33	25.12 ± 3.3 19.37 – 37.46
Gestational age			0.065
Mean ± SD Range	48.83 ± 8.00 35 – 62	50.19 ± 7.478 35 – 63
Gravidity			0.742
Gravida 1	46	54
Gravida 2	61	55
Gravida 3	22	22
Gravida 4	4	7
Gravida 5	86	81
Parity			0.891
Para 0	59	66
Para 1	57	52
Para 2	20	19
Para 3	3	4
Para 4	80	78
Previous cesarean section (CS)			0.117
No previous CS	92	116
1 previous CS	92	77
2 previous CS	21	19
3 previous CS	11	4
4 previous CS	3	3

[Table 2] has been corrected. Correct is:

Table 2 Comparison of failure rates between groups.

Failure rate	Group 1 (placebo)		Group 2 (letrozole)		Chi-square test
	n	%	n	%	p-value
No (complete miscarriage)	85	39	171	78	< 0.001
Yes (incomplete miscarriage)	134	61	48	22

[Table 3] has been corrected. Correct is:

Table 3 Comparison of onset and duration of vaginal bleeding and onset of passing products of conception (clinical data).

Clinical findings	Group 1 (placebo)	Group 2 (letrozole)	p-value
Time to 1st vaginal bleeding after administration of misoprostol, days			< 0.001
Mean ± SD Range	2.30 ± 0.64 1 – 4	1.33 ± 0.29 1 – 3
Time to induction of abortion after administration of misoprostol, days	3.09 ± 0.99	1.42 ± 0.50	< 0.001
Mean ± SD Range	2 – 7	1 – 2
Time to 1st product of conception passed after administration of misoprostol, days	3.50 ± 1.55	2.09 ± 0.70	< 0.001
Mean ± SD Range	2 – 9	1 – 7

[Table 4] has been corrected. Correct is:

Table 4 Comparison of side effects of medication.

Side effects	Group 1 (placebo)		Group 2 (letrozole)		Chi-square test
	No	%	No	%	p-value
Nausea and vomiting	7	3	37	17	0.002
Fever	16	7	9	4	0.152
Severe pain	15	7	24	11	0.132
Severe bleeding needing evacuation	48	22	36	16	0.141

Publikationsverlauf

Artikel online veröffentlicht:
07. November 2022