RSS-Feed abonnieren
Bitte kopieren Sie die angezeigte URL und fügen sie dann in Ihren RSS-Reader ein.
https://www.thieme-connect.de/rss/thieme/de/10.1055-s-00034924.xml
Nuklearmedizin 2022; 61(05): 416-417
DOI: 10.1055/a-1856-4290
DOI: 10.1055/a-1856-4290
Case Report
Successful PRRT-rechallenge in a metastasized neuroendocrine tumor of the middle ear
Erfolgreiche Rechallenge-PRRT eines metastasierten neuroendokrinen Tumors des Mittelohrs
Introduction
Commonly neuroendocrine tumors (NET) oft the middle ear are regarded as benign pathologies [1]. We present the case of a patient who not only suffered from repetitive local recurrences but also developed systemic metastases successfully treated by repeated peptide-receptor radionuclide-therapy (PRRT).
Publikationsverlauf
Eingereicht: 26. Januar 2022
Angenommen nach Revision: 12. Mai 2022
Artikel online veröffentlicht:
18. August 2022
© 2022. Thieme. All rights reserved.
Georg Thieme Verlag KG
Rüdigerstraße 14, 70469 Stuttgart, Germany
-
References
- 1 Torske KR, Thompson LD. Adenoma versus carcinoid tumor of the middle ear: a study of 48 cases and review of the literature. Mod Pathol 2002; 15 (05) 543-555 DOI: 10.1038/modpathol.3880561. (PMID: 12011260)
- 2 Ratnayake GM, Luong TV, Toumpanakis C. et al. Middle ear neuroendocrine tumours: Insight into their pathogenesis, diagnosis and management. J Neuroendocrinol 2021; 33 (09) e13031 DOI: 10.1111/jne.13031.. (PMID: 34462974)
- 3 Saliba I, Evrard AS. Middle ear glandular neoplasms: adenoma, carcinoma or adenoma with neuroendocrine differentiation: a case series. Cases J 2009; 02: 6508 DOI: 10.1186/1757-1626-0002-0000006508.. (PMID: 20111612)
- 4 Strosberg J, El-Haddad G, Wolin E. et al. Phase 3 Trial of (177)Lu-Dotatate for Midgut Neuroendocrine Tumors. N Engl J Med 2017; 376 (02) 125-135 DOI: 10.1056/NEJMoa1607427.. (PMID: 28076709)
- 5 Lima Ferreira J, Marques B, Menke-van der Houven van Oordt CW. et al. Treatment with somatostatin analogues and PRRT in metastatic middle ear adenoma with neuroendocrine features. Endocrinol Diabetes Metab Case Rep 2021; 20–0172 DOI: 10.1530/EDM-20-0172.
- 6 Rudisile S, Gosewisch A, Wenter V. et al. Salvage PRRT with 177Lu-DOTA-octreotate in extensively pretreated patients with metastatic neuroendocrine tumor (NET): dosimetry, toxicity, efficacy, and survival. BMC Cancer 2019; 19 (01) 788 DOI: 10.1186/s12885-019-6000-y. (PMID: 31395036)