Electrochemical Intramolecular Oxidative C(sp³)–H/C(sp³)–H Coupling for the Synthesis of 4-Quinolones

Abstract

An efficient electrochemical approach for the synthesis of 4-quinolones via intramolecular C(sp³)–H/C(sp³)–H cross-coupling has been developed under metal- and external oxidant-free conditions. This electrochemical approach provides a simple and efficient route to construct useful 4-quinolone derivatives in moderate to good yields.

Key words

electrochemical - C(sp³)–H/C(sp³)–H cross-coupling - 2-aryl-4-quinolones - chemical oxidant-free - undivided cell

Publication History

Received: 26 July 2022

Accepted after revision: 14 September 2022

Accepted Manuscript online:
14 September 2022

Article published online:
13 October 2022

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