Electrochemical Intramolecular Oxidative C(sp3)–H/C(sp3)–H Coupling for the Synthesis of 4-Quinolones

Jiwei Wu; Kejun Jin; Ruiyou Wang; Xingyu Wang; Xiaoxiao Yu; Liangcheng Zhong; Jianguo Liu

doi:10.1055/a-1942-7110

Synthesis, Table of Contents

Synthesis 2023; 55(03): 451-456
DOI: 10.1055/a-1942-7110

paper

Electrochemical Intramolecular Oxidative C(sp³)–H/C(sp³)–H Coupling for the Synthesis of 4-Quinolones

Jiwei Wu∗

,

Kejun Jin

,

Ruiyou Wang

,

Xingyu Wang

,

Xiaoxiao Yu

,

Liangcheng Zhong

,

Jianguo Liu

Abstract

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Abstract

An efficient electrochemical approach for the synthesis of 4-quinolones via intramolecular C(sp³)–H/C(sp³)–H cross-coupling has been developed under metal- and external oxidant-free conditions. This electrochemical approach provides a simple and efficient route to construct useful 4-quinolone derivatives in moderate to good yields.

Key words

electrochemical - C(sp³)–H/C(sp³)–H cross-coupling - 2-aryl-4-quinolones - chemical oxidant-free - undivided cell

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References

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