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Z Gastroenterol 2023; 61(04): 399-410
DOI: 10.1055/a-1957-7370
Übersicht

Ultrasound Elastography for Characterization of Focal Liver Lesions

Elastografie zur Charakterisierung von Lebertumoren
Yi Dong
1   Department of Ultrasound, Zhongshan Hospital Fudan University, Shanghai, China (Ringgold ID: RIN92323)
2   Department of Ultrasound, Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, China
,
Jonas Koch
3   Department Allgemeine Innere Medizin, Kliniken (DAIM) Hirslanden Beau Site, Salem und Permanence, Bern, Switzerland
,
Amjad Alhyari
4   Interdisciplinary Center of Ultrasound Diagnostics, University Hospital Giessen and Marburg, Gastroenterology, Endocrinology, Metabolism and Clinical Infectiology, Philipps University Marburg, Marburg, Germany (Ringgold ID: RIN61061)
,
Ehsan Safai Zadeh 
4   Interdisciplinary Center of Ultrasound Diagnostics, University Hospital Giessen and Marburg, Gastroenterology, Endocrinology, Metabolism and Clinical Infectiology, Philipps University Marburg, Marburg, Germany (Ringgold ID: RIN61061)
,
Christian Görg
4   Interdisciplinary Center of Ultrasound Diagnostics, University Hospital Giessen and Marburg, Gastroenterology, Endocrinology, Metabolism and Clinical Infectiology, Philipps University Marburg, Marburg, Germany (Ringgold ID: RIN61061)
,
Wen-Ping Wang
1   Department of Ultrasound, Zhongshan Hospital Fudan University, Shanghai, China (Ringgold ID: RIN92323)
,
Annalisa Berzigotti
5   Department of Visceral Surgery and Medicine, Bern University Hospital, University of Bern, Berne, Switzerland
,
Christoph F. Dietrich 
3   Department Allgemeine Innere Medizin, Kliniken (DAIM) Hirslanden Beau Site, Salem und Permanence, Bern, Switzerland
› Author AffiliationsSupported by: National Natural Science Foundation of China No. 82071942
Supported by: Shanghai Pujiang Program No. 2020PJD008
Supported by: Clinical Research Plan of SHDC No. SHDC2020CR4060, No. SHDC2020CR1031B
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Abstract

Focal liver lesions (FLL) are typically detected by conventional ultrasound or other imaging modalities. After the detection of FLL, further characterization is essential, and this can be done by contrast-enhanced imaging techniques, e.g., contrast-enhanced ultrasound (CEUS) and magnetic resonance imaging (MRI) or by means of biopsy with histological evaluation. Elastographic techniques are nowadays integrated into high-end ultrasound systems and their value for the detection of severe liver fibrosis and cirrhosis has been shown in studies and meta-analyses. The use of an ultrasound elastographic technique for the differentiation of malignant and benign liver tumors is less well-established. This review summarizes the current data on utility and performance of ultrasound elastography for the characterization of FLL.

Zusammenfassung

Fokale Leberläsionen (FLL) werden typischerweise durch konventionellen Ultraschall oder andere bildgebende Verfahren detektiert. Eine weitere Charakterisierung erfolgt durch kontrastverstärkte bildgebende Verfahren, z. B. kontrastverstärkter Ultraschall (CEUS) und Magnetresonanztomografie (MRT), oder durch Biopsie mit histologischer Untersuchung. Elastografische Techniken werden heute routinemäßig in Ultraschallsysteme integriert und ihr Wert für die Erkennung der fortgeschrittenen Leberfibrose und -zirrhose wurde in Studien, Metaanalysen und Leitlinien belegt. Weniger etabliert ist der Einsatz elastografischer Techniken zur Differenzierung bösartiger und gutartiger Lebertumoren. Dieser Review fasst die aktuellen Daten zur Bedeutung der Ultraschall-Elastografie zur Charakterisierung von FLL zusammen.

Schlüsselwörter

Elastografie - fokale Leberläsionen - Lebertumoren - Steifheit - Ultraschall

Keywords

Elastography - focal liver lesions - liver tumors - stiffness - Ultrasound


Publication History

Received: 25 November 2021

Accepted: 06 October 2022

Article published online:
14 December 2022

© 2022. Thieme. All rights reserved.

Georg Thieme Verlag KG
Rüdigerstraße 14, 70469 Stuttgart, Germany

 

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