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Geriatrie up2date 2022; 4(04): 261-273
DOI: 10.1055/a-1965-2280
Neurologie und Psychiatrie

Schlaf und Schlafstörungen im hohen Lebensalter

Helmut Frohnhofen
,
Roland Popp
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Schlaf und Schlafverhalten ändern sich mit zunehmendem Lebensalter. Überlagert werden diese Veränderungen von Komorbiditäten, die ihrerseits den Schlaf beeinflussen. Schlafstörungen sind häufig imhöheren Lebensalter und belasten die Betroffenen stark, da sie die Tagesbefindlichkeit und die kognitive und psychische Leistungsfähigkeit beeinträchtigen, die Lebensqualität reduzieren und das Erscheinungsbild geriatrischer Syndrome verändern. Diagnostisch und therapeutisch ist oft ein individualisiertes Vorgehen erforderlich.
Kernaussagen

  • Schlafstörungen treten im höheren Lebensalter häufig auf.

  • Schlafstörungen müssen von den altersphysiologischen Veränderungen des Schlafs abgegrenzt werden.

  • Schlafstörungen sind stark belastend, da sie die Tagesbefindlichkeit sowie die kognitive und psychische Leistungsfähigkeit beeinträchtigen, die Lebensqualität reduzieren und geriatrische Syndrome in ihrem Erscheinungsbild modifizieren.

  • Eine differenzierte Abklärung und Behandlung lohnen sich auch bei betagten Menschen, machen diagnostisch und therapeutisch aber oft ein individualisiertes Vorgehen erforderlich.



Publication History

Article published online:
21 November 2022

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  • Literatur

  • 1 Bloom HG, Ahmed I, Alessi CA. et al. Evidence-based recommendations for the assessment and management of sleep disorders in older persons. J Am Geriat Soc 2009; 57 (05) 761-789
    CrossrefPubMedSearch in Google Scholar
  • 2 Ohayon MM, Carskadon MA, Guilleminault C. et al. Meta-analysis of quantitative sleep parameters from childhood to old age in healthy individuals: developing normative sleep values across the human lifespan. Sleep 2004; 27 (07) 1255-1273
    CrossrefPubMedSearch in Google Scholar
  • 3 Ito E, Inoue Y. The International Classification of Sleep Disorders, third edition. American Academy of Sleep Medicine. Includes bibliographies and index. Nihon rinsho. Jpn J Clin Medcine 2015; 73 (06) 916-923
    Search in Google Scholar
  • 4 Ancoli-Israel S. Insomnia in the elderly: a review for the primary care practitioner. Sleep 2000; 23 (Suppl. 01) S23-S30 Discussion: S36–S38
    PubMedSearch in Google Scholar
  • 5 Ohayon MM, Vecchierini MF. Daytime sleepiness and cognitive impairment in the elderly population. Arch Intern Med 2002; 162 (02) 201-208
    CrossrefPubMedSearch in Google Scholar
  • 6 Bahr K, Cámara RJA, Gouveris H. et al. Current treatment of comorbid insomnia and obstructive sleep apnea with CBTI and PAP-therapy: a systematic review. Frontiers in neurology 2018; 9: 804
    CrossrefPubMedSearch in Google Scholar
  • 7 Riemann D, Baum E, Cohrs S. et al. S3-Leitlinie Nicht erholsamer Schlaf/Schlafstörungen. Insomnie bei Erwachsenen. Somnologie 2017; 21: 2-44
    CrossrefSearch in Google Scholar
  • 8 Foley DJ, Monjan AA, Brown SL. et al. Sleep complaints among elderly persons: an epidemiologic study of three communities. Sleep 1995; 18 (06) 425-432
    CrossrefPubMedSearch in Google Scholar
  • 9 Cochen V, Arbus C, Soto ME. et al. Sleep disorders and their impacts on healthy, dependent, and frail older adults. J Nutrit Health Ageing 2009; 13 (04) 322-329
    CrossrefPubMedSearch in Google Scholar
  • 10 Wehling M, Burkhardt H, Kuhn-Thiel A. et al. VALFORTA: A randomised trial to validate the FORTA (Fit fOR The Aged) classification. Age Ageing 2016; 45 (02) 262-267
    CrossrefPubMedSearch in Google Scholar
  • 11 Rissardo JP, Caprara ALF. Mirtazapine-Associated movement disorders: A literature review. Tzu Chi Med J 2020; 32 (04) 318-330
    CrossrefPubMedSearch in Google Scholar
  • 12 Yaffe K, Laffan AM, Harrison SL. et al. Sleep-disordered breathing, hypoxia, and risk of mild cognitive impairment and dementia in older women. JAMA 2011; 306 (06) 613-619
    CrossrefPubMedSearch in Google Scholar
  • 13 Frohnhofen H, Roffe C. Intermittent nocturnal hypoxemia in individuals with dementia: prevalence and relationship with functional status. J Am Geriat Soc 2012; 60 (10) 1997-1999
    CrossrefPubMedSearch in Google Scholar
  • 14 Kitamura T, Miyazaki S, Sulaiman HB. et al. Insomnia and obstructive sleep apnea as potential triggers of dementia: is personalized prediction and prevention of the pathological cascade applicable?. EPMA J 2020; 11 (03) 355-365
    CrossrefPubMedSearch in Google Scholar
  • 15 Mayer G, Fietze I, Fischer J. et al. S3-Leitlinie Nicht erholsamer Schlaf/Schlafstörungen: Kurzfassung. Berlin, Heidelberg: Springer; 2011
    CrossrefSearch in Google Scholar
  • 16 Johns MW. A new method for measuring daytime sleepiness: The Epworth sleepiness scale. Sleep 1991; 14 (06) 540-545
    Search in Google Scholar
  • 17 Gronewold J, Lenuck MCI, Gülderen I. et al. Developing an alternative version of the Epworth sleepiness scale to assess daytime sleepiness in adults with physical or mental disabilities. Gerontology 2021; 67 (01) 49-59
    CrossrefPubMedSearch in Google Scholar
  • 18 Ancoli-Israel S, Palmer BW, Cooke JR. et al. Cognitive effects of treating obstructive sleep apnea in Alzheimerʼs disease: a randomized controlled study. J Am Geriat Soc 2008; 56 (11) 2076-2081
    CrossrefPubMedSearch in Google Scholar
  • 19 Frohnhofen H, Hoeltmann B, Orth G. Acceptance of NCPAP in a sample of patients admitted for geriatric rehabilitation. European journal of medical research 2009; 14 (Suppl. 04) 82-85
    CrossrefPubMedSearch in Google Scholar
  • 20 Netzer NC, Ancoli-Israel S, Bliwise DL. et al. Principles of practice parameters for the treatment of sleep disordered breathing in the elderly and frail elderly: The consensus of the International Geriatric Sleep Medicine Task Force. Eur Respirat J 2016; 48 (04) 992-1018
    CrossrefPubMedSearch in Google Scholar
  • 21 Bruni O, DelRosso LM, Melegari MG. et al. The Parasomnias. Child Adolesc Psychiat Clin North Am 2021; 30 (01) 131-142
    CrossrefPubMedSearch in Google Scholar
  • 22 Gilat M, Marshall NS, Testelmans D. et al. A critical review of the pharmacological treatment of REM sleep behavior disorder in adults: time for more and larger randomized placebo-controlled trials. J Neurol 2021;
    CrossrefPubMedSearch in Google Scholar
  • 23 Mishima K, Okawa M, Hishikawa Y. et al. Morning bright light therapy for sleep and behavior disorders in elderly patients with dementia. Acta Psychiat Scand 1994; 89 (01) 1-7
    CrossrefPubMedSearch in Google Scholar
  • 24 Lemoine P, Nir T, Laudon M. et al. Prolonged-release melatonin improves sleep quality and morning alertness in insomnia patients aged 55 years and older and has no withdrawal effects. J sleep Res 2007; 16 (04) 372-380
    CrossrefPubMedSearch in Google Scholar
  • 25 Rothdach AJ, Trenkwalder C, Haberstock J. et al. Prevalence and risk factors of RLS in an elderly population: The MEMO study. Memory and Morbidity in Augsburg Elderly. Neurology 2000; 54 (05) 1064-1068
    CrossrefPubMedSearch in Google Scholar
  • 26 Garcia-Borreguero D, Williams AM. An update on restless legs syndrome (Willis-Ekbom disease): Clinical features, pathogenesis and treatment. Curr Opin Neurol 2014; 27 (04) 493-501
    CrossrefPubMedSearch in Google Scholar
  • 27 Pizza F, Antelmi E, Vandi S. et al. The distinguishing motor features of cataplexy: a study from video recorded attacks. Sleep 2018; 41
    CrossrefPubMedSearch in Google Scholar
  • 28 Mander BA, Marks SM, Vogel JW. et al. β-amyloid disrupts human NREM slow waves and related hippocampus-dependent memory consolidation. Nature Neurosci 2015; 18 (07) 1051-1057
    CrossrefPubMedSearch in Google Scholar
  • 29 Spira AP, Gamaldo AA, An Y. et al. Self-reported sleep and beta-amyloid deposition in community-dwelling older adults. JAMA Neurol 2013; 70 (12) 1537-1543
    PubMedSearch in Google Scholar
  • 30 Gehrman P, Marler M, Martin JL. et al. The relationship between dementia severity and rest/activity circadian rhythms. Neuropsychiat Dis Treat 2005; 1 (02) 155-163
    CrossrefPubMedSearch in Google Scholar
  • 31 Gronewold J, Haensel R, Kleinschnitz C. et al. Sleep-disordered breathing in hospitalized geriatric patients with mild dementia and its association with cognition, emotion and mobility. Int J Environ Res Public Health 2019; 16 (05) 863
    CrossrefPubMedSearch in Google Scholar
  • 32 Vitiello MV, Borson S. Sleep disturbances in patients with Alzheimerʼs disease: epidemiology, pathophysiology and treatment. CNS Drugs 2001; 15 (10) 777-796
    CrossrefPubMedSearch in Google Scholar
  • 33 Martin JL, Webber AP, Alam T. et al. Daytime sleeping, sleep disturbance, and circadian rhythms in the nursing home. Am J Geriat Psychiat 2006; 14 (02) 121-129
    CrossrefPubMedSearch in Google Scholar
  • 34 Gallagher-Thompson D, Brooks JO, Bliwise D. et al. The relations among caregiver stress, „sundowning“ symptoms, and cognitive decline in Alzheimerʼs disease. J Am Geriat Soc 1992; 40 (08) 807-810
    CrossrefPubMedSearch in Google Scholar
  • 35 Ancoli-Israel S, Klauber MR, Jones DW. et al. Variations in circadian rhythms of activity, sleep, and light exposure related to dementia in nursing-home patients. Sleep 1997; 20 (01) 18-23
    PubMedSearch in Google Scholar
  • 36 Guarnieri B, Adorni F, Musicco M. et al. Prevalence of sleep disturbances in mild cognitive impairment and dementing disorders: a multicenter Italian clinical cross-sectional study on 431 patients. Dement Geriat Cognit Disorders 2012; 33 (01) 50-58
    CrossrefPubMedSearch in Google Scholar
  • 37 Frohnhofen H, Mayer G, Gronewold J. Schlaf und Schlafstörungen bei Demenzerkrankungen. Dtsch Med Wochenschr 2021; 146 (11) 719-722
    Thieme ConnectPubMedSearch in Google Scholar