Borylation of Alkenyl Carbamates by Means of Sodium Metal

Shunsuke Koyama; Fumiya Takahashi; Hayate Saito; Hideki Yorimitsu

doi:10.1055/a-1970-4584

Synthesis, Table of Contents

Synthesis 2023; 55(11): 1744-1751
DOI: 10.1055/a-1970-4584

paper

Special Issue dedicated to Prof. Cristina Nevado, recipient of the 2021 Dr. Margaret Faul Women in Chemistry Award

Borylation of Alkenyl Carbamates by Means of Sodium Metal

Shunsuke Koyama

,

Fumiya Takahashi

,

Hayate Saito

,

Hideki Yorimitsu ∗

Abstract

All articles of this category

Abstract

Treatment of alkenyl carbamates with sodium dispersion and a co-existing boron electrophile affords alkenylboronates via the reductive cleavage of the vinylic C–O bond. The key to this borylation is an instant trapping of reactive organosodium species with the co-existing boron electrophile.

Key words

alkenyl carbamate - sodium dispersion - borylation - alkenylboronate - electron transfer

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References

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