Lokale Antibiotikatherapie in der Orthopädie und Unfallchirurgie

Yves Gramlich; Matthias Schnetz; Reinhard Hoffmann

doi:10.1055/a-1989-0565

Zeitschrift für Orthopädie und Unfallchirurgie, Table of Contents

Z Orthop Unfall 2023; 161(05): 563-583
DOI: 10.1055/a-1989-0565

CME-Fortbildung

Lokale Antibiotikatherapie in der Orthopädie und Unfallchirurgie

Was gibt es Neues 50 Jahre nach Entwicklung der Antibiotikakette? Article in several languages: deutsch | English

Yves Gramlich

,

Matthias Schnetz

,

Reinhard Hoffmann

Abstract

2022 jährte sich die Entwicklung der Antibiotikakette zum 50. Mal. Die Beladung von Knochenzementen mit Antibiotika war ein herausragender Fortschritt in der Behandlung muskuloskelettaler Infektionen; das Verfahren ist heute noch bewährter Standard. Die Erforschung wie auch Verwendung neuartiger Antibiotikaträger ist weiterhin ein wichtiger Bestandteil der Forschung im Kontext muskuloskelettaler Infektionen. Der Artikel gibt einen Überblick über die verschiedenen erhältlichen lokalen Antibiotika und deren Spezifika. Darüber hinaus werden aktuelle angepasste Behandlungskonzepte besprochen.

Schlüsselwörter

Antibiotikaträger - PMMA - Antibiotikakette - muskuloskelettale Infektion - periprothetische Infektion - implantatassoziierte Infektion - lokale Antibiotikatherapie - Cerament

Full Text

References

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