Conjugate Addition of Organoboron Compounds to α,β-Unsaturated Ketones Catalyzed by Nickelacycles

Abstract

The catalytic activity of nickelacycles in the conjugate addition of arylboronates to α,β-unsaturated ketones was investigated. Nickelacycles afforded β-arylated ketones in moderate to high yields, whereas an analogous palladacycle did not catalyze the reaction. Studies on the time course of the reaction confirmed that the nickelacycles act as active species in the conjugate addition reaction.

Key words

nickelacycles - nickel catalysis - organoboron compounds - enones - conjugate addition

Publication History

Received: 19 June 2023

Accepted after revision: 08 August 2023

Accepted Manuscript online:
08 August 2023

Article published online:
21 September 2023

• References and Notes

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