Okklusion der Vena saphena parva durch Myofibrome bei zirkumskripter Sklerodermie

Wir berichten über den seltenen Fall eines 20-jährigen Patienten, der sich konsiliarisch mit Myofibromen in den Venae saphenae parvae und linksseitiger Varikose vorstellte. Differenzialdiagnostisch erinnerten die Myofibrome sonografisch an einliegendes Thrombusmaterial. Als Nebendiagnose war eine zirkumskripte Sklerodermie bekannt. Das Krankheitsbild des Myofibroms wird erläutert, und mögliche Zusammenhänge zwischen den Erkrankungen werden diskutiert.

Abstract

We report a rare case of a 20-year-old patient with bilateral myofibromas of the small saphenous veins and varicose veins. In terms of differential diagnosis, the myofibromas sonographically resembled embedded thrombus material. The patient was known to have circumscribed scleroderma as a secondary diagnosis. The disease myofibroma is explained and possible links between the diseases are discussed.

Schlüsselwörter

Okklusion - Vena saphena parva - Myofibrome - zirkumskripte Sklerodermie - Varikose

Keywords

occlusion - small saphenous vein - myofibromas - circumscribed scleroderma - varicose veins

• Literatur

• 1 Kamino H, Reddy VB, Gero M. et al. Dermatomyofibroma. A benign cutaneous, plaque-like proliferation of fibroblasts and myofibroblasts in young adults. J Cutan Pathol 1992; 19: 85-93
• 2 Stanford D, Rogers M. Dermatological presentations of infantile myofibromatosis: a review of 27 cases. Australas J Dermatol 2000; 41: 156-161
• 3 Campagnolo OA, Morais CF, Ughini MO. et al. Dermatomyofibroma. An Bras Dermatol 2017; 92: 101-103
• 4 Kutzner H, Hugel H, Rutten A. et al. Acquired benign myofibroma of the skin (adult myofibroma). Hautarzt 1993; 44: 561-568
• 5 Laaff H, Wokalek H, Schopf E. Cutaneous myofibroma – late manifestations. Hautarzt 1990; 41: 617-619
• 6 Guitart J, Ritter JH, Wick MR. Solitary cutaneous myofibromas in adults: report of six cases and discussion of differential diagnosis. J Cutan Pathol 1996; 23: 437-444
• 7 Hugel H. Plaque-like dermal fibromatosis. Hautarzt 1991; 42: 223-226
• 8 (DDG) DDGeV. AWMF S2k-Leitlinie Diagnostik und Therapie der zirkumskripten Sklerodermie Version 3.0 (12.10.2023). Accessed December 28, 2023 at: https://register.awmf.org/assets/guidelines/013–066l_S2k_zirkumskripte_Sklerodermie_2023–11_1.pdf
• 9 Marzano AV, Menni S, Parodi A. et al. Localized scleroderma in adults and children. Clinical and laboratory investigations on 239 cases. Eur J Dermatol 2003; 13: 171-176
• 10 Ludwig RJ, Werner RJ, Winker W. et al. Chronic venous insufficiency – a potential trigger for localized scleroderma. J Eur Acad Dermatol Venereol 2006; 20: 96-99
• 11 English 3rd JC, Derdeyn AS, Smith PD. et al. Adult acral cutaneous myofibromas in a patient with generalized morphea. J Am Acad Dermatol 2002; 46: 953-956
• 12 Pepper MA, Theparee T, Messenger EA. et al. Cutaneous acral myofibroma with PDGFRB mutation in a patient with linear morphea en coup de sabre. J Cutan Pathol 2021; 48: 1097-1100