Author commentary on Pernille T. Larsen et al.

Pernille T. Larsen et al. Detection of colorectal cancer and advanced neoplasia during first surveillance interval after detection of adenomas in fecal immunochemical test cancer screening: a nationwide study

Participants who underwent fecal immunochemical test (FIT) screening with adenoma findings and a follow-up colonoscopy (n = 10 068) were categorized as high risk (surveillance after 1 year) or intermediate risk (surveillance after 3 years). The intermediate risk group (n = 5504) were further categorized as no surveillance (NS) or surveillance (S), based on the 2020 European Society of Gastrointestinal Endoscopy guidelines. Colorectal cancer was found in 0.59% of high risk vs. 1.11% intermediate risk patients, and in 1.69% of intermediate-NS vs. 0.87% intermediate-S patients. This study finds that the first colonoscopy after a FIT screening may not sufficiently guide surveillance and underlines that continued efforts to improve colonoscopy quality are essential.

Publication History

Article published online:
30 October 2024