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Endoscopy 2025; 57(01): 68-73
DOI: 10.1055/a-2350-4059
Innovations and brief communications

Prospective feasibility study of a novel rigidizing stabilizing overtube in the resection of complex gastrointestinal polyps

Salmaan Jawaid
1   Division of Gastroenterology, Hepatology and Nutrition, Baylor College of Medicine, Houston, United States
,
Ahmed F. Aboelezz 
2   Department of Internal Medicine, Gastroenterology and Hepatology Unit, Tanta University, Tanta, Egypt
,
Gehad Daba
1   Division of Gastroenterology, Hepatology and Nutrition, Baylor College of Medicine, Houston, United States
,
Mai Khalaf
1   Division of Gastroenterology, Hepatology and Nutrition, Baylor College of Medicine, Houston, United States
,
Fares Ayoub
1   Division of Gastroenterology, Hepatology and Nutrition, Baylor College of Medicine, Houston, United States
,
Noor Zabad
1   Division of Gastroenterology, Hepatology and Nutrition, Baylor College of Medicine, Houston, United States
,
Michael Mercado 
1   Division of Gastroenterology, Hepatology and Nutrition, Baylor College of Medicine, Houston, United States
,
Tara Keihanian
1   Division of Gastroenterology, Hepatology and Nutrition, Baylor College of Medicine, Houston, United States
,
Mohamed Othman 
1   Division of Gastroenterology, Hepatology and Nutrition, Baylor College of Medicine, Houston, United States
› Author Affiliations Clinical Trial: Registration number (trial ID): NCT05141032, Trial registry: ClinicalTrials.gov (http://www.clinicaltrials.gov/), Type of Study: Prospective
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Corrected by:

Correction: Prospective feasibility study of a novel rigidizing stabilizing overtube in the resection of complex gastrointestinal polypsEndoscopy eFirst
DOI: 10.1055/a-2388-5444

Referred to by:

Overtubes: a bridge to successful colonoscopic resection?Endoscopy 2025; 57(01): 74-76
DOI: 10.1055/a-2386-9098

Abstract

Background A novel rigidizing overtube (ROT) was developed to facilitate endoscopic removal of complex gastrointestinal polyps. We aimed to prospectively evaluate the efficacy and safety of the device in the management of large gastrointestinal polyps.

Methods A prospective, single-center study, conducted between May 2021 and April 2023, enrolled patients undergoing endoscopic resection of colon/duodenal polyps ≥25 mm. Primary outcomes were safety, technical success, and clinical success defined as the ability of ROT to facilitate endoscopic polyp removal without changing the initial resection method.

Results 97 patients (98 polyps), with a mean polyp size of 33.2 mm (median 31.1), were evaluated. Technical and clinical success rates were 100% and 84%, respectively. Ileocecal valve location was the only predictor of clinical failure (P = 0.02). The mean time to reach the lesion was 7.2 minutes (95%CI 5–8), with overall resection and procedure times of 53.6 minutes (95%CI 48–61) and 88.9 minutes (95%CI 79–95), respectively. No device-related adverse events occurred. Lower technical (67%) and clinical (67%) success rates were seen for duodenal polyps (n = 6).

Conclusion The novel ROT was safe, with high technical and clinical success during resection of complex colon polyps. Future studies will determine timing of implementation during routine endoscopic resection.

Supplementary Material



Publication History

Received: 06 October 2023

Accepted after revision: 10 June 2024

Article published online:
11 July 2024

© 2024. Thieme. All rights reserved.

Georg Thieme Verlag KG
Oswald-Hesse-Straße 50, 70469 Stuttgart, Germany

 

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