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Nephrologie aktuell 2024; 28(10): 456-462
DOI: 10.1055/a-2375-2571
Schwerpunkt
Nephrologie

Analyse des Mineral-Puffer-Systems des Blutes

Ein neuer Ansatz zur Beurteilung des CKD-MBD-Syndroms
Daniel Cejka
1   Interne 3 – Nieren- und Hochdruckerkrankungen, Transplantationsmedizin, Rheumatologie, Ordensklinikum Linz Elisabethinen, Linz, Österreich
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ZUSAMMENFASSUNG

Ein neuer Ansatz zur Beurteilung des CKD-MBD-Syndroms (CKD-MBD: „chronic kidney disease – mineral bone disorder“) ist die Messung des Mineral-Puffer-Systems des Blutes. Mittels der Messung von endogenen Kalziproteinpartikeln (CPP: „calciprotein particles“) und der Bestimmung der CPP-Kristallisations-Zeit ex vivo (T50-Test) kann der Gesamtzustand des Mineral-Puffer-Systems des Blutes festgestellt werden. In Zukunft könnte die Optimierung des Mineral-Puffer-Systems die bisherigen Parameter – Phosphat, Kalzium, Parathormon (PTH) – ersetzen. Entsprechende klinische Studien sind allerdings noch erforderlich.



Publication History

Article published online:
12 December 2024

© 2024. Thieme. All rights reserved.

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