Abstract
Background Bronchoplastic resections are now widely used as a surgical treatment for resectable
central lung cancer. However, bronchial dehiscence is one of the most life-threatening
complications, making it important to identify its risk factors to separate patients
who require more attention during the postoperative period.
Methods The data of 285 patients who underwent bronchoplasty from 2006 to 2021 were retrospectively
reviewed. We collected demographic characteristics, history of neoadjuvant therapy,
preoperative assessment, perioperative outcomes, and postoperative complications to
investigate different variables as risk factors for bronchial dehiscence by univariate
and multivariate analyses.
Results Bronchial dehiscence was diagnosed in 12 patients (4.2%) with a mean presentation
on postoperative day 10 (range: 1–24 days). By multivariate analysis, current smoking
(odds ratio [OR]: 4.8, 95% confidence interval [CI]: 1.1–20.1, p = 0.032), chronic obstructive pulmonary disease (COPD; OR: 6.5, 95% CI: 1.2–33.8,
p = 0.027), bronchoplastic right lower lobectomy (OR: 12.9, 95% CI: 2.4–69.7, p = 0.003), and upper sleeve bilobectomy with segmentectomy S6 by performing an anastomosis
between right main bronchus (RMB) and bronchus of basal pyramid (BP) (OR: 30.4, 95%
CI: 3.4–268.1, p = 0.002) were confirmed as relevant risk factors for developing bronchial dehiscence.
Conclusion Current smoking, COPD, bronchoplastic right lower lobe, and upper l with segmentectomy
S6 by performing an anastomosis between RMB and bronchus of BP were identified with
the occurrence of bronchial dehiscence after sleeve resection.
Keywords
lung cancer treatment (surgery medical) - surgery - complications
